anti-Mouse (Murine) NGFR antibody for Enzyme Immunoassay

Recommended NGFR Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor Receptor (NGFR) Antibodies
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
  • nerve growth factor receptor
  • neurotrophin receptor associated death domain
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • NGFR
  • nradd
  • Ngfr
  • ngfr
Reactivity
Human, Mouse (Murine)
268
109
98
30
28
26
24
12
10
10
8
6
5
5
3
3
2
2
2
1
Host
Rabbit
137
123
34
4
1
Clonality
Polyclonal
Conjugate
This NGFR antibody is un-conjugated
19
15
15
13
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
201
110
110
81
66
55
40
32
15
14
13
6
6
6
4
3
3
1
1
1
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Catalog No. ABIN5555045
$ 375.38
Plus shipping costs $45.00

General

Antigen Nerve Growth Factor Receptor (NGFR) Antibodies
Reactivity Human, Mouse (Murine)
(268), (109), (98), (30), (28), (26), (24), (12), (10), (10), (8), (6), (5), (5), (3), (3), (2), (2), (2), (1)
Host Rabbit
(137), (123), (34), (4), (1)
Clonality
Polyclonal
Conjugate This NGFR antibody is un-conjugated
(19), (15), (15), (13), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(201), (110), (110), (81), (66), (55), (40), (32), (15), (14), (13), (6), (6), (6), (4), (3), (3), (1), (1), (1)
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Product Details anti-NGFR Antibody

Target Details NGFR Application Details Handling Images
Specificity This antibody detects CD271 / NGFR.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Peptide affinity chromatography
Immunogen NGFR antibody was raised against purified recombinant human NGFR.
Isotype IgG

Target Details NGFR

Product Details anti-NGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD271 / NGFR (NGFR Antibody Abstract)
Background The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases (reviewed in 1). Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family (2). Also known as the low-affinity receptor p75NTR, this receptor is involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination (reviewed in 3). Its ligands include NGF, brain-derived neurotrophic factor (BDNF), NT3, and NT4 (4). NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane domains and thus can function as a co-receptor that refines Trk affinity and specificity for neurotrophins (5). Finally, upon binding of various neurotrophins, NGFR associates with tumor necrosis factor receptor-6 (TRAF6), suggesting that it can potentially function as a signal transducer for NGF signals through NGFR (6).Synonyms: TNFRSF16, Tumor necrosis factor receptor superfamily member 16
Gene ID 4804
NCBI Accession NP_002498
UniProt P08138
Research Area Growth Factors, Receptors
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-NGFR Antibody Target Details NGFR Handling Images back to top
Application Notes ELISA. Western blot: 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NGFR Antibody Target Details NGFR Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.