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|Antigen||Protein Kinase A, alpha (PRKACA) Antibodies|
|Conjugate||This PRKACA antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-PRKACA AntibodyTarget Details PRKACA Application Details Handling References for anti-PRKACA antibody (ABIN453298) Images
|Specificity||This antibody reacts to PRKACA.|
|Purification||Saturated Ammonium Sulfate (SAS) precipitation|
|Immunogen||KLH conjugated synthetic peptide selected from the N-terminal(K282) region of human PRKACA|
Target Details PRKACAProduct Details anti-PRKACA Antibody Application Details Handling References for anti-PRKACA antibody (ABIN453298) Images back to top
|Alternative Name||PRKACA (PRKACA Antibody Abstract)|
|Background||PRKACA phosphorylates a large number of substrates in the cytoplasm and the nucleus.Synonyms: PKA C-alpha, cAMP-dependent protein kinase catalytic subunit alpha|
|Research Area||Cancer, Kinases/Phosphatases|
|Pathways||NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals|
Application DetailsProduct Details anti-PRKACA Antibody Target Details PRKACA Handling References for anti-PRKACA antibody (ABIN453298) Images back to top
ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-PRKACA Antibody Target Details PRKACA Application Details References for anti-PRKACA antibody (ABIN453298) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-PRKACA antibody (ABIN453298)Product Details anti-PRKACA Antibody Target Details PRKACA Application Details Handling Images back to top
Sugiyama, Chen, Hunter, Taffs, Sitkovsky: "The dual role of the cAMP-dependent protein kinase C alpha subunit in T-cell receptor-triggered T-lymphocytes effector functions." in: The Journal of biological chemistry, Vol. 267, Issue 35, pp. 25256-63, 1993
ImagesProduct Details anti-PRKACA Antibody Target Details PRKACA Application Details Handling References for anti-PRKACA antibody (ABIN453298) back to top