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Browse our anti-RANK (CD265) Antibodies

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anti-RANK Antibodies (CD265)
On are 87 RANK (CD265) Antibodies from 9 different suppliers available. Additionally we are shipping RANK Kits (16) and RANK Proteins (11) and many more products for this protein. A total of 114 RANK products are currently listed.
list all antibodies Gene Name GeneID UniProt
CD265 21934 O35305
CD265 8792 Q9Y6Q6
CD265 498206  

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Most Popular Reactivities for anti-RANK (CD265) Antibodies

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anti-Mouse (Murine) RANK Antibodies:

anti-Human RANK Antibodies:

anti-Rat (Rattus) RANK Antibodies:

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Top referenced anti-RANK Antibodies

  1. Human Monoclonal RANK Primary Antibody for WB - ABIN2668967 : Hikita, Kadono, Chikuda, Fukuda, Wakeyama, Yasuda, Nakamura, Oda, Miyazaki, Tanaka: Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against RANK Interaction Partners

Mouse (Murine) RANK (CD265) interaction partners

  1. present study shows that ginsenoside Rg3 protects against LPS (show TLR4 Antibodies)-induced acute lung injury through inactivating the NF-kappaB (show NFKB1 Antibodies) signaling

  2. In palmatine-treated mice, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) expression decreased. In the culture supernatant of MC3T3-E1 cells, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) levels were significantly reduced by palmatine addition.

  3. Results show that moderate increases in affinity for RANK lead to a substantial augmentation of osteoclast formation, signaling, and bone resorption suggesting a biphasic relationship between RANKL (show TNFSF11 Antibodies)/RANK affinity and osteoclastogenic capacity.

  4. Dissection of the mechanism by which this occurs indicates that mCripto-1 activates receptor activator NF-kappaB (show NFKB1 Antibodies)/receptor activator NF-kappaB (show NFKB1 Antibodies) ligand, and NF-kappaB (show NFKB1 Antibodies) signaling pathways.

  5. We also show that R-spondin1 (show RSPO1 Antibodies) is depleted in RANK-null progenitors, and that its exogenous administration rescues key aspects of RANK deficiency by reinstating a WNT (show WNT2 Antibodies) response and mammary cell expansion

  6. findings have uncovered a tumorigenic role for RANKL (show TNFSF11 Antibodies)/RANK in the salivary gland and suggest that targeting this pathway may represent a novel therapeutic intervention approach in the prevention and/or treatment of this understudied head and neck cancer

  7. results indicate that the RANK IVVY motif cooperates with the TRAF (show TRAF1 Antibodies)-binding motifs to promote osteoclastogenesis, which provides novel insights into the molecular mechanism of RANK signaling in osteoclastogenesis.

  8. findings suggest CCN2 (show CTGF Antibodies) as a candidate of the fourth factor in the RANK/RANKL/OPG (show TNFSF11 Antibodies) system for osteoclastogenesis, which regulates OPG (show TNFSF11 Antibodies) and RANK via direct interaction

  9. Recapitulating the W434X mutation by transcription activator-like effector nuclease (show DCLRE1C Antibodies)-mediated targeted disruption of Tnfrsf11a (show TNFRSF11A Antibodies) within the region homologous to W434X in the macrophage-like cell line RAW264.7 impaired formation of osteoclast-like cells.

  10. silencing angiopoietin-like protein 4 (show ANGPTL4 Antibodies) protects against LPS (show TLR4 Antibodies)-induced acute lung injury via regulating SIRT1 (show SIRT1 Antibodies)/NF-kB signaling pathway

Human RANK (CD265) interaction partners

  1. Twenty-one single-nucleotide polymorphisms (SNPs) of TNFSF11, TNFRSF11A, and TNFRSF11B were genotyped. This study suggests that TNFRSF11B but not TNFSF11 and TNFRSF11A genetic polymorphisms are associated with Type 2 Diabetes Mellitus in Southern Han Chinese women.

  2. the OPG/RANKL (show TNFSF11 Antibodies)/RANK system might be directly influenced by genetic variants of NOTCH1 (show NOTCH1 Antibodies) in aortic valve calcification.

  3. Postmenopausal women with Rheumatoid Arthritis, carrying either the RANKL (show TNFSF11 Antibodies)-290T allele or possessing the RANK 575CC genotype were more likely to develop osteoporosis.

  4. The RANK/RANKL (show TNFSF11 Antibodies) system induces chemoresistance.

  5. RANK and CCR6 (show CCR6 Antibodies) expressed on monocytes may be novel targets for the regulation of bone resorption in rheumatoid arthritis and osteoporosis.

  6. Results demonstrated that the type of inflammatory infiltrate present in periradicular cysts appears to influence the expression of RANK, RANKL (show TNFSF11 Antibodies), and osteoprotegerin (show TNFRSF11B Antibodies)

  7. Study showed that endogenous RANK expression changes might influence prostate cancer cell behavior since reduced RANK expression resulted in significantly increased PC-3 (show PCSK1 Antibodies) cell proliferation and adhesion.

  8. expression of OPG (show TNFRSF11B Antibodies), RANK and RANKL (show TNFSF11 Antibodies) genes exert a crucial role in the progression of avascular necrosis

  9. Src (show SRC Antibodies) expression showed a significantly positive linear relationship with RANK, suggesting a potential mechanism of the RANKL (show TNFSF11 Antibodies)-RANK axis in regulating breast cancer cell differentiation and antiapoptosis.

  10. high level of mRANKL/RANK expression in cervical cancer lesions plays an important role in the rapid growth of cervical cancer cells possibly through strengthening the dialogue between cervical cancer cells and regulation of IL-8 (show IL8 Antibodies) secretion

RANK (CD265) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Alternative names and synonyms associated with RANK (CD265)

  • tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a) antibody
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (TNFRSF11A) antibody
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (Tnfrsf11a) antibody
  • CD265 antibody
  • FEO antibody
  • LOH18CR1 antibody
  • Ly109 antibody
  • mRANK antibody
  • ODFR antibody
  • OFE antibody
  • OPTB7 antibody
  • OSTS antibody
  • PDB2 antibody
  • RANK antibody
  • RGD1563614 antibody
  • TRANCE-R antibody
  • TRANCER antibody

Protein level used designations for anti-RANK (CD265) Antibodies

osteoclast differentiation factor receptor , receptor activator of NF-KB , receptor activator of NF-kappaB , tumor necrosis factor receptor superfamily member 11A , loss of heterozygosity, 18, chromosomal region 1 , receptor activator of nuclear factor-kappa B

21934 Mus musculus
8792 Homo sapiens
498206 Rattus norvegicus
483957 Canis lupus familiaris
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