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Browse our SLC39A3 (SLC39A3) ELISA Kits

Full name:
Solute Carrier Family 39 (Zinc Transporter), Member 3 ELISA Kits (SLC39A3)
On www.antibodies-online.com are 1 Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) ELISA Kits from 1 different suppliers available. Additionally we are shipping SLC39A3 Antibodies (28) and SLC39A3 Proteins (3) and many more products for this protein. A total of 36 SLC39A3 products are currently listed.
Synonyms:
A170, AI845814, OSIL, p60, p62, p62B, PDB3, Zip3
list all ELISA KIts Gene Name GeneID UniProt
SLC39A3 8878 Q13501
Mouse SLC39A3 SLC39A3 106947 Q99K24
Rat SLC39A3 SLC39A3 314637 Q5U1X7

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Human Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) interaction partners

  1. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  2. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  3. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

  4. findings expand the SQSTM1 (show SQSTM1 ELISA Kits)-associated phenotypic spectrum and lend further support to the concept of disturbed selective autophagy pathways in neurodegenerative diseases

  5. Aldo was revealed to induce autophagy, as indicated by the increased conversion from microtubuleassociated protein 1A/1Blight chain 3 (LC3)I to LC3II, the increased expression levels of autophagyrelated gene 7 (Atg7) and the increased degradation of p62, which was accompanied by MC proliferation

  6. Results demonstrate that p62 (show GTF2H1 ELISA Kits) facilitates activation of NRF2 (show GABPA ELISA Kits) and mTORC1 and is essential for hepatocellular carcinomas (HCC (show FAM126A ELISA Kits)) initiation. High levels of p62 (show GTF2H1 ELISA Kits) accumulation in non-tumor liver tissue in early-stage HCC (show FAM126A ELISA Kits) patients.

  7. Results show that Nrf2 (show GABPA ELISA Kits) prevents TM-induced apoptotic cell death and that TM promotes p62 (show GTF2H1 ELISA Kits)-dependent autophagic Keap1 (show KEAP1 ELISA Kits) degradation, leading to Nrf2 (show GABPA ELISA Kits) activation. In addition, we identified that p62 (show GTF2H1 ELISA Kits) is essential to protect cells against TM-mediated oxidative damage through Nrf2 (show GABPA ELISA Kits) activation.

  8. Spinal stenosis emerges as a prominent phenotype in SQSTM1 (show SQSTM1 ELISA Kits) P392L-positive men with aging

  9. p62 is a crucial positive regulator of HIF1alpha, which is a facilitating factor in p62-enhanced tumorigenesis.

  10. SQSTM1 (show SQSTM1 ELISA Kits) mutations were initially associated with Paget disease of bone (PDB), they have been also identified in FTD (show FTL ELISA Kits)(familial frontotemporal dementia).

Mouse (Murine) Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3) interaction partners

  1. ZnT3 (show Slc30a3 ELISA Kits) KO mice showed abnormality in trace fear conditioning is involved in associative fear memory and extinction, but not in innate fear.

  2. Znt-3-deficient mice lacking synaptic Zn also show less hippocampal cell damage following kainic acid injection. Zip transporters may provide selective therapeutic targets to protect these neurons from early Zn-induced neurodegeneration following injury.

  3. The expression of zinc transporter 3 (ZnT3 (show Slc30a3 ELISA Kits)) starts early in development, lasts throughout embryonic life, and is detected in proliferative and differentiating areas of the brain in distinct chelatable vesicular zinc pools.

  4. ZnT3 (show Slc30a3 ELISA Kits)-immunoreactive ependymal cells possess secretory activity directed towards the central canal.

  5. ZIP1 (show SLC39A1 ELISA Kits), ZIP2 (show Slc39a2 ELISA Kits) and ZIP3 may play cell-specific roles in zinc homeostasis rather than primary roles in the acquisition of dietary zinc

  6. ZIP1 (show SLC39A1 ELISA Kits) and ZIP3 zinc uptake transporter activity is controlled by zinc-stimulated endocytosis

  7. Reduced expression of Zip3 ultimately resulted in cell death, indicating that mammary epithelial cells have a unique requirement for Zip3-mediated Zn(2+) import.

  8. Knockout mice lacking Zip3 were generated and characterized.

  9. Mutations in the ZIP1 (show SLC39A1 ELISA Kits) and ZIP3 zinc transporter genes are silent when dietary intake of zinc is normal, but can dramatically compromise the success of pregnancy when dietary intake of zinc is limiting.

  10. temporal and spatial patterns of expression of the mouse ZIP1 (show SLC39A1 ELISA Kits), 3, 4, and 5 genes in the developing intestine and the effects of maternal dietary zinc deficiency on these patterns of expression were examined

SLC39A3 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SLC39A3

  • sequestosome 1 (SQSTM1) Elisa Kit
  • solute carrier family 39 (zinc transporter), member 3 (SLC39A3) Elisa Kit
  • solute carrier family 39 (zinc transporter), member 3 (Slc39a3) Elisa Kit
  • A170 Elisa Kit
  • AI845814 Elisa Kit
  • OSIL Elisa Kit
  • p60 Elisa Kit
  • p62 Elisa Kit
  • p62B Elisa Kit
  • PDB3 Elisa Kit
  • Zip3 Elisa Kit

Protein level used designations for SLC39A3

EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , sequestosome-1 , ubiquitin-binding protein p62 , ZIP-3 , solute carrier family 39 member 3 , zinc transporter ZIP3 , zrt- and Irt-like protein 3

GENE ID SPECIES
8878 Homo sapiens
29985 Homo sapiens
106947 Mus musculus
314637 Rattus norvegicus
505294 Bos taurus
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