Browse our anti-SQSTM1 (SQSTM1) Antibodies

Full name:
anti-Sequestosome 1 Antibodies (SQSTM1)
On www.antibodies-online.com are 307 Sequestosome 1 (SQSTM1) Antibodies from 23 different suppliers available. Additionally we are shipping SQSTM1 Proteins (14) and SQSTM1 Kits (8) and many more products for this protein. A total of 344 SQSTM1 products are currently listed.
Synonyms:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3
list all antibodies Gene Name GeneID UniProt
SQSTM1 8878 Q13501
SQSTM1 18412 Q64337
SQSTM1 113894 O08623

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anti-Human SQSTM1 Antibodies:

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anti-Rat (Rattus) SQSTM1 Antibodies:

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Top referenced anti-SQSTM1 Antibodies

  1. Human Polyclonal SQSTM1 Primary Antibody for IF, IHC (p) - ABIN388979 : Seibenhener, Babu, Geetha, Wong, Krishna, Wooten: Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. in Molecular and cellular biology 2004 (PubMed)
    Show all 22 references for 388979

  2. Human Polyclonal SQSTM1 Primary Antibody for WB - ABIN1881829 : Visconti, Langston, Alonso, Goodman, Selby, Fraser, Ralston: Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 (PubMed)
    Show all 5 references for 1881829

  3. Human Polyclonal SQSTM1 Primary Antibody for DB - ABIN1881831 : Ding, Ni, Li, Liao, Chen, Stolz, Dorn, Yin: Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 1881831

  4. Human Polyclonal SQSTM1 Primary Antibody for IF (p), IHC (p) - ABIN682153 : Cui, Luo, Li, Li, Wang: Changes of intracellular Ca2+ in quercetin-induced autophagy progression. in Acta biochimica et biophysica Sinica 2015 (PubMed)
    Show all 4 references for 682153

  5. Human Monoclonal SQSTM1 Primary Antibody for IF, ELISA - ABIN393579 : Xia, Liu, Xie, Zhu, Guerra, Shen, Yeddula, Fischer, Low, Zhou, Zhang, Oldfield, Verma: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin. in Science translational medicine 2014 (PubMed)

  6. Human Polyclonal SQSTM1 Primary Antibody for ICC, IF - ABIN449246 : Zhang, Gui, Huang, Deng, Fang, Ke, He, Li, Fang: Neuroprotective Effects of β-Asarone Against 6-Hydroxy Dopamine-Induced Parkinsonism via JNK/Bcl-2/Beclin-1 Pathway. in Molecular neurobiology 2016 (PubMed)

  7. Human Polyclonal SQSTM1 Primary Antibody for ICC, IF - ABIN449244 : Eason, Bell, Marshall, Rodgers, Pineda, Steiger, Al-Riyami, Harnett, Harnett: The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ. in Scientific reports 2016 (PubMed)

  8. Human Monoclonal SQSTM1 Primary Antibody for ELISA, FACS - ABIN4343162 : Shen, Chen, He, Chen, Song, Xiao, Wan, Dai, Pan, Wang: Inhibition of ERα/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. in Oncotarget 2016 (PubMed)

More Antibodies against SQSTM1 Interaction Partners

Human Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (show FAM126A Antibodies)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

  3. p62/SQSTM1, which accumulates in autophagy-defective cells, directly binds to and inhibits nuclear RNF168 (show RNF168 Antibodies), an E3 ligase essential for histone H2A ubiquitination and DNA damage responses. As a result, DNA repair proteins such as BRCA1, RAP80 (show UIMC1 Antibodies), and Rad51 (show RAD51 Antibodies) cannot be recruited to the sites of DNA double-strand breaks (DSBs), which impairs DSB repair.

  4. propose that the interplay between LRRK2 (show LRRK2 Antibodies) and p62 (show GTF2H1 Antibodies) may contribute to the pathophysiological function and homeostasis of LRRK2 (show LRRK2 Antibodies) protein

  5. Frontotemporal dementia -linked mutations in gene p62/SQSTM1 encoding autophagy adaptor proteins , indicate that impaired autophagy might cause Frontotemporal dementia.

  6. These data suggest that SQSTM1 mutations are not a common cause of normal tension glaucoma.

  7. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  8. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  9. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  10. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

Mouse (Murine) Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (show FAM126A Antibodies)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. SQSTM1 or damaged proteins may be transported from the nose to the brain. These findings strongly implicate widespread protein damage in the etiology of flavorings-related lung disease.

  3. Promoting amino acid sensitivity of the mTOR pathway is dependent on p62 accumulation by inhibition of autophagy and this process plays an important role in the hepatic differentiation of stem/progenitor cells.

  4. role of p62 (show GTF2H1 Antibodies) in MDB (show ABR Antibodies) maturation and stability

  5. two ALS-linked factors, SQSTM1 and ALS2 (show ALS2 Antibodies), have distinct but additive protective roles against mutant SOD1 (show SOD1 Antibodies)-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system.

  6. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  7. results indicate that autophagy is important for the removal of excess Endoplasmic Reticulum and hepatic CYP enzymes in mouse livers, a process associated with the autophagy receptor protein p62.

  8. p62 (show GTF2H1 Antibodies) reduces UVB-induced apoptosis by modulating intrinsic apoptotic signaling through Src (show SRC Antibodies) phosphorylation.

  9. Our results indicate that JEV replication is impaired in p62-deficient MEFs, suggesting that p62 positively regulates JEV replication in host cells.

  10. Results demonstrate that p62 (show GTF2H1 Antibodies) facilitates activation of NRF2 (show NFE2L2 Antibodies) and mTORC1 and is essential for hepatocellular carcinomas (HCC (show FAM126A Antibodies)) initiation.

Zebrafish Sequestosome 1 (SQSTM1) interaction partners

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) antibody
  • sequestosome 1 (LOC100342157) antibody
  • sqstm1 protein (sqstm1) antibody
  • sequestosome 1 (Sqstm1) antibody
  • sequestosome 1 (sqstm1) antibody
  • A170 antibody
  • MGC79491 antibody
  • OSF-6 antibody
  • Osi antibody
  • OSIL antibody
  • p60 antibody
  • p62 antibody
  • p62B antibody
  • PDB3 antibody
  • sb:cb621 antibody
  • sqstm1 antibody
  • STAP antibody
  • zgc:85784 antibody
  • ZIP antibody
  • ZIP3 antibody

Protein level used designations for anti-Sequestosome 1 (SQSTM1) Antibodies

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPECIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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