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Browse our anti-SQSTM1 (SQSTM1) Antibodies

Full name:
anti-Sequestosome 1 Antibodies (SQSTM1)
On www.antibodies-online.com are 206 Sequestosome 1 (SQSTM1) Antibodies from 21 different suppliers available. Additionally we are shipping SQSTM1 Proteins (15) and SQSTM1 Kits (6) and many more products for this protein. A total of 241 SQSTM1 products are currently listed.
Synonyms:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3
list all antibodies Gene Name GeneID UniProt
SQSTM1 8878 Q13501
SQSTM1 18412 Q64337
SQSTM1 113894 O08623

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Top referenced anti-SQSTM1 Antibodies

  1. Human Polyclonal SQSTM1 Primary Antibody for IF, IHC (p) - ABIN388979 : Seibenhener, Babu, Geetha, Wong, Krishna, Wooten: Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. in Molecular and cellular biology 2004 (PubMed)
    Show all 22 references for ABIN388979

  2. Human Polyclonal SQSTM1 Primary Antibody for EIA, IF - ABIN1449619 : Chu, Wang, Wu, Lei: Invasion and multiplication of Helicobacter pylori in gastric epithelial cells and implications for antibiotic resistance. in Infection and immunity 2010 (PubMed)
    Show all 12 references for ABIN1449619

  3. Human Polyclonal SQSTM1 Primary Antibody for WB - ABIN1881829 : Visconti, Langston, Alonso, Goodman, Selby, Fraser, Ralston: Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010 (PubMed)
    Show all 5 references for ABIN1881829

  4. Human Polyclonal SQSTM1 Primary Antibody for EIA, IHC (p) - ABIN497992 : Hocking, Lucas, Daroszewska, Mangion, Olavesen, Cundy, Nicholson, Ward, Bennett, Wuyts, Van Hul, Ralston: Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease. in Human molecular genetics 2002 (PubMed)
    Show all 5 references for ABIN497992

  5. Human Polyclonal SQSTM1 Primary Antibody for DB - ABIN1881830 : Ding, Ni, Li, Liao, Chen, Stolz, Dorn, Yin: Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881830

  6. Human Polyclonal SQSTM1 Primary Antibody for DB - ABIN1881831 : Jain, Lamark, Sjøttem, Larsen, Awuh, Øvervatn, McMahon, Hayes, Johansen: p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881831

  7. Human Polyclonal SQSTM1 Primary Antibody for IF (p), IHC (p) - ABIN682153 : Cui, Luo, Li, Li, Wang: Changes of intracellular Ca2+ in quercetin-induced autophagy progression. in Acta biochimica et biophysica Sinica 2015 (PubMed)

  8. Human Monoclonal SQSTM1 Primary Antibody for IF, ELISA - ABIN393579 : Xia, Liu, Xie, Zhu, Guerra, Shen, Yeddula, Fischer, Low, Zhou, Zhang, Oldfield, Verma: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin. in Science translational medicine 2014 (PubMed)

More Antibodies against SQSTM1 Interaction Partners

Human Sequestosome 1 (SQSTM1) interaction partners

  1. The authors show in a fully reconstituted system that the interaction of p62 (show GTF2H1 Antibodies) with ubiquitin and LC3B (show MAP1LC3B Antibodies) is sufficient to bend the membrane around the cargo.

  2. p62 (show GTF2H1 Antibodies) is a novel binding partner for ARIP4 (show RAD54L2 Antibodies), and that its binding regulates the cellular protein level of ARIP4 (show RAD54L2 Antibodies) under conditions of metabolic stress.

  3. Our results revealed that oxLDL was dynamically associated with autophagy and 100 mug/ml oxLDL blocked autophagic flux in THP-1 (show GLI2 Antibodies) cells.

  4. Bcl-2 directly interacts with the N-terminus of p62, but not the C-terminus (UBA domain). Bcl-2 affects the affinity of p62 to poly-ubiquitin chains.

  5. The incidence of ALS (show IGFALS Antibodies) caused by the SQSTM1 mutation has increased from 30 to 35 worldwide.

  6. TRIM21 plays an essential role in p62-regulated redox homeostasis and may be a viable target for treating pathological conditions resulting from oxidative damage.

  7. An increased expression of AMBRA1 (show AMBRA1 Antibodies) and SQSTM1.

  8. Data suggest a substantial gene-environment interaction that the emergence of Paget's disease of bone in offspring inheriting SQSTM1 mutations is delayed by at least a decade.

  9. Cell hypoxia enhances the complex formation between p62 and androgen receptor by promoting phosphorylation of p62 at serine 403.

  10. our findings suggest the existence of a so-far unrecognized quality control mechanism involving BAG3 (show BAG3 Antibodies), HSPB8 (show HSPB8 Antibodies) and p62/SQSTM1 for accurate remodelling of actin-based mitotic structures that guide spindle orientation.

Mouse (Murine) Sequestosome 1 (SQSTM1) interaction partners

  1. p62 (show GTF2H1 Antibodies) is a novel binding partner for ARIP4 (show RAD54L2 Antibodies), and that its binding regulates the cellular protein level of ARIP4 (show RAD54L2 Antibodies) under conditions of metabolic stress.

  2. p62 (show GTF2H1 Antibodies) is recruited together with ubiquitin to the T. gondii PVs (show PVRL2 Antibodies), following IFN-gamma (show IFNG Antibodies) stimulation, and plays a specific role in vacuolar-antigen-specific CD8 (show CD8A Antibodies)+ T cell activation.

  3. Study shows that NF-kappaB (show NFKB1 Antibodies) exerts its anti-inflammatory activity by inducing delayed accumulation of the autophagy receptor p62/SQSTM1.

  4. TRIM21 plays an essential role in p62-regulated redox homeostasis and may be a viable target for treating pathological conditions resulting from oxidative damage.

  5. The p62 (show GTF2H1 Antibodies) double conditional knockout mice demonstrated that p62 (show GTF2H1 Antibodies) aggregate formation triggers aberrant superoxide increases by impairing superoxide dismutase (show SOD1 Antibodies) functions.

  6. PKCzeta (show PRKCZ Antibodies)/p62 (show GTF2H1 Antibodies) activation stimulated inflammatory cytokine production and enhanced IGF-I (show IGF1 Antibodies)-stimulated VSMC proliferation

  7. High expression of cytoplasmic p62 is a novel prognostic biomarker of endometrial cancers

  8. Findings suggest that p62 (show GTF2H1 Antibodies) and neighbor of the brca1 (show BRCA1 Antibodies) gene affect the pathogenesis of neurodegenerative diseases through the cooperative modulation of alpha-synuclein (show SNCA Antibodies) aggregation.

  9. These results indicate that p62 (show GTF2H1 Antibodies) plays an important role in protecting cells against oxidative stress through Keap1 (show KEAP1 Antibodies) degradation-mediated Nrf2 (show NFE2L2 Antibodies) activation.

  10. Lack of p62 (show GTF2H1 Antibodies) attenuates the palmitic acid-mediated Nrf2 (show NFE2L2 Antibodies) activation and increases the susceptibility of cells to oxidative stress.

Zebrafish Sequestosome 1 (SQSTM1) interaction partners

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) antibody
  • sequestosome 1 (LOC100342157) antibody
  • sqstm1 protein (sqstm1) antibody
  • sequestosome 1 (Sqstm1) antibody
  • sequestosome 1 (sqstm1) antibody
  • A170 antibody
  • MGC79491 antibody
  • OSF-6 antibody
  • Osi antibody
  • OSIL antibody
  • p60 antibody
  • p62 antibody
  • p62B antibody
  • PDB3 antibody
  • sb:cb621 antibody
  • sqstm1 antibody
  • STAP antibody
  • zgc:85784 antibody
  • ZIP antibody
  • ZIP3 antibody

Protein level used designations for anti-Sequestosome 1 (SQSTM1) Antibodies

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPECIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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