anti-Human SQSTM1 antibody for Dot Blot

Recommended SQSTM1 Antibody (supplied by: Log in to see )

Antigen
Sequestosome 1 (SQSTM1) Antibodies
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sequestosome 1 L homeolog
  • SQSTM1
  • sqstm1
  • Sqstm1
  • sqstm1.L
Epitope
pSer403
52
40
22
19
18
18
18
18
17
17
15
14
12
11
8
8
6
5
5
5
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
330
151
100
8
5
5
5
4
4
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
255
68
4
3
Clonality
Polyclonal
Conjugate
This SQSTM1 antibody is un-conjugated
18
17
17
11
11
10
8
8
8
6
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB)
264
138
96
85
79
65
52
34
33
14
13
4
4
3
2
Options
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Catalog No. ABIN1881831
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
29.605053 ABIN1881830 DB Rabbit pSer207 Log in to see Polyclonal 5
1 ABIN1957423 DB ELISA HRP Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN1957336 DB ELISA HRP Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1956211 DB ELISA FITC Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN1954962 DB ELISA Biotin Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1958542 DB ELISA PE Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN1958440 DB ELISA PE Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1956112 DB ELISA FITC Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1953769 DB ELISA APC Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN1952795 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1953667 DB ELISA APC Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN1952897 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN1955047 DB ELISA Biotin Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN2572547 DB ELISA Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN2572546 DB ELISA Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN2366206 DB ELISA APC Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN2366208 DB ELISA FITC Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN2366209 DB ELISA HRP Rabbit IgG pSer207 Log in to see Polyclonal
1 ABIN2366215 DB ELISA HRP Rabbit IgG pSer403 Log in to see Polyclonal
1 ABIN2366216 DB ELISA PE Rabbit IgG pSer403 Log in to see Polyclonal

General

Antigen Sequestosome 1 (SQSTM1) Antibodies
Epitope pSer403
(52), (40), (22), (19), (18), (18), (18), (18), (17), (17), (15), (14), (12), (11), (8), (8), (6), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(330), (151), (100), (8), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(255), (68), (4), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This SQSTM1 antibody is un-conjugated
(18), (17), (17), (11), (11), (10), (8), (8), (8), (6), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Dot Blot (DB)
(264), (138), (96), (85), (79), (65), (52), (34), (33), (14), (13), (4), (4), (3), (2)
Pubmed 5 references available
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Product Details anti-SQSTM1 Antibody

Target Details SQSTM1 Application Details Handling References for anti-SQSTM1 antibody (ABIN1881831) Images
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1.
Clone RB41445

Target Details SQSTM1

Product Details anti-SQSTM1 Antibody Application Details Handling References for anti-SQSTM1 antibody (ABIN1881831) Images back to top
Antigen
Alternative Name SQSTM1 (SQSTM1 Antibody Abstract)
Background This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Synonyms: SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62
NCBI Accession NP_001135771, NP_001135770, NP_003891
UniProt Q13501
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy

Application Details

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Handling References for anti-SQSTM1 antibody (ABIN1881831) Images back to top
Application Notes DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details References for anti-SQSTM1 antibody (ABIN1881831) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-SQSTM1 antibody (ABIN1881831)

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Handling Images back to top
Product cited in:

Visconti, Langston, Alonso, Goodman, Selby, Fraser, Ralston: "Mutations of SQSTM1 are associated with severity and clinical outcome in paget disease of bone." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 25, Issue 11, pp. 2368-73, 2010

Ding, Ni, Li, Liao, Chen, Stolz, Dorn, Yin: "Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 27879-90, 2010

Jain, Lamark, Sjøttem, Larsen, Awuh, Øvervatn, McMahon, Hayes, Johansen: "p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22576-91, 2010

Lau, Wang, Zhao, Villeneuve, Wu, Jiang, Sun, White, Zhang: "A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62." in: Molecular and cellular biology, Vol. 30, Issue 13, pp. 3275-85, 2010

Gao, Cao, Bao, Zuo, Xie, Cai, Fu, Zhang, Wu, Zhang, Chen: "Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation." in: Nature cell biology, Vol. 12, Issue 8, pp. 781-90, 2010

Images

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Handling References for anti-SQSTM1 antibody (ABIN1881831) back to top
Supplier Images
Dot Blot (DB) image for anti-Sequestosome 1 (SQSTM1) (pSer403) antibody (ABIN1881831) Dot blot analysis of SQSTM1 Antibody (Phospho S403) Phospho-specific Pab (ABIN1881831...