anti-Human SQSTM1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended SQSTM1 Antibody (supplied by: Log in to see )

Antigen
Sequestosome 1 (SQSTM1) Antibodies
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sqstm1 protein
  • SQSTM1
  • LOC100342157
  • sqstm1
  • Sqstm1
Epitope
AA 80-130
52
40
22
19
19
18
18
17
17
17
14
14
12
11
8
7
6
5
5
5
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
325
150
99
8
5
5
5
4
4
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
252
66
4
3
Clonality
Polyclonal
Conjugate
This SQSTM1 antibody is un-conjugated
18
17
17
11
10
10
8
8
8
6
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
260
138
96
84
80
64
52
35
33
14
12
4
4
3
2
Options
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Catalog No. ABIN682153
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2806648 IF (p) Alexa Fluor 594 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN682157 IF (p) Cy5 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN682158 IF (p) Cy5.5 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN682159 IF (p) Cy7 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN682156 IF (p) Cy3 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN682160 IF (p) FITC Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN916350 IF (p) Alexa Fluor 555 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN916348 IF (p) Alexa Fluor 350 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN916349 IF (p) Alexa Fluor 488 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN916351 IF (p) Alexa Fluor 647 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN5010968 IF (p) Alexa Fluor 750 Rabbit IgG AA 80-130 Log in to see Polyclonal
1 ABIN5010967 IF (p) Alexa Fluor 680 Rabbit IgG AA 80-130 Log in to see Polyclonal

General

Antigen Sequestosome 1 (SQSTM1) Antibodies
Epitope AA 80-130
(52), (40), (22), (19), (19), (18), (18), (17), (17), (17), (14), (14), (12), (11), (8), (7), (6), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(325), (150), (99), (8), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(252), (66), (4), (3)
Clonality
Polyclonal
Conjugate This SQSTM1 antibody is un-conjugated
(18), (17), (17), (11), (10), (10), (8), (8), (8), (6), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(260), (138), (96), (84), (80), (64), (52), (35), (33), (14), (12), (4), (4), (3), (2)
Pubmed 4 references available
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Product Details anti-SQSTM1 Antibody

Target Details SQSTM1 Application Details Handling ProductDetails: References for anti-SQSTM1 antibody (ABIN682153) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SQSTM1/Ubiquitin-binding protein p62
Isotype IgG

Target Details SQSTM1

Product Details anti-SQSTM1 Antibody Application Details Handling ProductDetails: References for anti-SQSTM1 antibody (ABIN682153) Images back to top
Antigen
Alternative Name Sqstm1 (SQSTM1 Antibody Abstract)
Background

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

Subcellular location: Cytoplasm, Nucleus

Synonyms: p60, p62, A170, OSIL, PDB3, ZIP3, p62B, Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, SQSTM1, ORCA

Gene ID 8878
UniProt Q13501
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy

Application Details

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Handling ProductDetails: References for anti-SQSTM1 antibody (ABIN682153) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details ProductDetails: References for anti-SQSTM1 antibody (ABIN682153) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-SQSTM1 antibody (ABIN682153)

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Handling Images back to top
Product cited in:

Kuo, Weng, Chang, Huang, Lin, Chuang, Lin, Liou, Tai, Lin, Wang: "Altered mitochondrial dynamics and response to insulin in cybrid cells harboring a diabetes-susceptible mitochondrial DNA haplogroup." in: Free radical biology & medicine, Vol. 96, pp. 116-29, 2016

Xia, Gao, Zhang, Wang, Zhao, Che, Ao, Yang, Wang, Lei: "Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells." in: Cell death discovery, Vol. 2, pp. 15065, 2016

Cui, Luo, Li, Li, Wang: "Changes of intracellular Ca2+ in quercetin-induced autophagy progression." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 11, pp. 908-14, 2015

Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: "?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice." in: Brain research, Vol. 1552, pp. 41-54, 2014

Images

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Handling ProductDetails: References for anti-SQSTM1 antibody (ABIN682153) back to top
Supplier Images
ELISA image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:3...
Immunohistochemistry (IHC) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) Formalin-fixed and paraffin embedded rat brain labeled with Anti-SQSTM1 Polyclonal An...
SDS-PAGE (SDS) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) L1 rat kidney lysates, L2 rat brain lysates probed : Anti-GDF9 (ABIN682153) at 1:200 ...
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) HeLa cell lysates probed with Anti-SQSTM1 Polyclonal Antibody, Unconjugated at 1:500...
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (AA 80-130) antibody (ABIN682153) L1 rat kidney lysates, L2 rat brain lysates probed : Anti-GDF9 at 1:200 in 4˚C. Foll...