Browse our anti-TNFRSF11A (TNFRSF11A) Antibodies

On are 134 Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) Antibodies from 21 different suppliers available. Additionally we are shipping TNFRSF11A Kits (34) and TNFRSF11A Proteins (23) and many more products for this protein. A total of 200 TNFRSF11A products are currently listed.
list all antibodies Gene Name GeneID UniProt
TNFRSF11A 498206  
TNFRSF11A 21934 O35305
TNFRSF11A 8792 Q9Y6Q6

Most Popular Reactivities for anti-TNFRSF11A (TNFRSF11A) Antibodies

anti-Rat (Rattus) TNFRSF11A Antibodies:

anti-Mouse (Murine) TNFRSF11A Antibodies:

anti-Human TNFRSF11A Antibodies:

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More Antibodies against TNFRSF11A Interaction Partners

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) interaction partners

  1. Data suggest that mutations at position I248 in DE-loop of murine RANKL (show TNFSF11 Antibodies) have effects on interaction of RANKL (show TNFSF11 Antibodies) with RANK and on subsequent activation of osteoclastogenesis by this hetero-multimer. (RANKL (show TNFSF11 Antibodies) = osteoclast differentiation factor (show TNFSF11 Antibodies); RANK = tumor necrosis factor (show TNF Antibodies) receptor superfamily, member 11a protein)

  2. The persistence of bone erosion and synovial osteoclasts in Rank-deficient mice, and the ability of TNF (show TNF Antibodies)/IL-6 (show IL6 Antibodies) to induce osteoclastogenesis, suggest that more than one cytokine pathway exists to generate these bone-resorbing cells in inflamed joints.

  3. Muscle RANK deletion had no significant effects on the sham or denervated slow-twitch soleus muscles. These data identify a novel role for RANK as a key regulator of Ca(2 (show CA2 Antibodies)+)storage and SERCA (show ATP2A3 Antibodies) activity, ultimately affecting denervated skeletal muscle function.

  4. present study shows that ginsenoside Rg3 protects against LPS (show TLR4 Antibodies)-induced acute lung injury through inactivating the NF-kappaB (show NFKB1 Antibodies) signaling

  5. In palmatine-treated mice, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) expression decreased. In the culture supernatant of MC3T3-E1 cells, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) levels were significantly reduced by palmatine addition.

  6. Results show that moderate increases in affinity for RANK lead to a substantial augmentation of osteoclast formation, signaling, and bone resorption suggesting a biphasic relationship between RANKL (show TNFSF11 Antibodies)/RANK affinity and osteoclastogenic capacity.

  7. Dissection of the mechanism by which this occurs indicates that mCripto-1 activates receptor activator NF-kappaB (show NFKB1 Antibodies)/receptor activator NF-kappaB (show NFKB1 Antibodies) ligand, and NF-kappaB (show NFKB1 Antibodies) signaling pathways.

  8. We also show that R-spondin1 (show RSPO1 Antibodies) is depleted in RANK-null progenitors, and that its exogenous administration rescues key aspects of RANK deficiency by reinstating a WNT (show WNT2 Antibodies) response and mammary cell expansion

  9. findings have uncovered a tumorigenic role for RANKL (show TNFSF11 Antibodies)/RANK in the salivary gland and suggest that targeting this pathway may represent a novel therapeutic intervention approach in the prevention and/or treatment of this understudied head and neck cancer

  10. results indicate that the RANK IVVY motif cooperates with the TRAF (show TRAF1 Antibodies)-binding motifs to promote osteoclastogenesis, which provides novel insights into the molecular mechanism of RANK signaling in osteoclastogenesis.

Human Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) interaction partners

  1. RANK/RANKL (show TNFSF11 Antibodies) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin (show TNFRSF11B Antibodies) to prevent bone metastasis.

  2. In histologically normal tissue of BRCA1-mutation carriers and showed that RANK(+) cells are highly proliferative, have grossly aberrant DNA repair and bear a molecular signature similar to that of basal-like breast cancer.

  3. In this review, we will provide a summary of the biological functions of RANK signaling pathway (receptor activator of nuclear factor kappaB ligand RANKL (show TNFSF11 Antibodies) and its receptor RANK ) and downstream pathways in bone remodeling, immunity and epithelial homeostasis, with a particular emphasis on cancer

  4. Our results suggest that the polymorphism of the RANKL (show TNFSF11 Antibodies), RANK, and OPG (show TNFRSF11B Antibodies) genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

  5. Vav3 (show VAV3 Antibodies) is a novel TRAF6 (show TRAF6 Antibodies) interaction partner that functions in the activation of cooperative signaling between T6BSs and the IVVY motif in the RANK signaling complex.

  6. OPG (show TNFRSF11B Antibodies) rs2073618, RANK rs75404003, and RANKL (show TNFSF11 Antibodies) rs9594782 single nucleotide poymorphisms may predispose LVH in thalassemia patients.

  7. Twenty-one single-nucleotide polymorphisms (SNPs) of TNFSF11, TNFRSF11A, and TNFRSF11B were genotyped. This study suggests that TNFRSF11B but not TNFSF11 and TNFRSF11A genetic polymorphisms are associated with Type 2 Diabetes Mellitus in Southern Han Chinese women.

  8. the OPG/RANKL (show TNFSF11 Antibodies)/RANK system might be directly influenced by genetic variants of NOTCH1 (show NOTCH1 Antibodies) in aortic valve calcification.

  9. Postmenopausal women with Rheumatoid Arthritis, carrying either the RANKL (show TNFSF11 Antibodies)-290T allele or possessing the RANK 575CC genotype were more likely to develop osteoporosis.

  10. The RANK/RANKL (show TNFSF11 Antibodies) system induces chemoresistance.

TNFRSF11A Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Alternative names and synonyms associated with TNFRSF11A

  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (Tnfrsf11a) antibody
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator (TNFRSF11A) antibody
  • tumor necrosis factor receptor superfamily, member 11a (Tnfrsf11a) antibody
  • CD265 antibody
  • FEO antibody
  • LOH18CR1 antibody
  • Ly109 antibody
  • mRANK antibody
  • ODFR antibody
  • OFE antibody
  • OPTB7 antibody
  • OSTS antibody
  • PDB2 antibody
  • Rank antibody
  • RGD1563614 antibody
  • TNFRSF11A antibody
  • TRANCE-R antibody
  • TRANCER antibody

Protein level used designations for TNFRSF11A

tumor necrosis factor receptor superfamily member 11A , tumor necrosis factor receptor superfamily, member 11a, NFKB activator , receptor activator of nuclear factor-kappa B , tumor necrosis factor receptor superfamily member 11A-like , osteoclast differentiation factor receptor , receptor activator of NF-KB , receptor activator of NF-kappaB , loss of heterozygosity, 18, chromosomal region 1

498206 Rattus norvegicus
468560 Pan troglodytes
483957 Canis lupus familiaris
530884 Bos taurus
769909 Gallus gallus
100358260 Oryctolagus cuniculus
100433235 Pongo abelii
21934 Mus musculus
8792 Homo sapiens
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