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|Application / Reactivity||Human|
|Biochemical Assay (BCA)||1 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Flow Cytometry (FACS)||53 Antibodies|
|Functional Studies (Func)||2 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunofluorescence (IF)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||21 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||2 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||4 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||21 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Intracellular Flow Cytometry (ICFC)||3 Antibodies|
|Mass Cytometry (CyTOF)||1 Antibodies|
|Western Blotting (WB)||57 Antibodies|
|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies|
|Conjugate||This TNFRSF13C antibody is conjugated to FITC Alternatives|
Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-TNFRSF13C AntibodyTarget Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images
|Purification||The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.|
Target Details TNFRSF13CProduct Details anti-TNFRSF13C Antibody Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
|Alternative Name||CD268 (TNFRSF13C Antibody Abstract)|
|Background||B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.|
Application DetailsProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Protect from prolonged exposure to light. Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-TNFRSF13C Antibody (ABIN2661625)Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling Images back to top
Rodig, Shahsafaei, Li et al.: "BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders." in: Human pathology, Vol. 36, Issue 10, pp. 1113-9, 2005 (PubMed).
Ye, Wang, Wells et al.: "BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses." in: European journal of immunology, Vol. 34, Issue 10, pp. 2750-9, 2004 (PubMed).
Ng, Sutherland, Newton et al.: "B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 807-17, 2004 (PubMed).
Thompson, Bixler, Qian et al.: "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF." in: Science (New York, N.Y.), Vol. 293, Issue 5537, pp. 2108-11, 2001 (PubMed).
ImagesProduct Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) back to top