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anti-Human TNFRSF13C antibody for Functional Studies

Recommended TNFRSF13C Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
  • 2010006P15Rik
  • BAFF-R
  • Baffr
  • BAFFR
  • Bcmd
  • Bcmd-1
  • Bcmd1
  • BROMIX
  • CD268
  • CVID4
  • Lvis22
  • prolixin
  • RGD1560810
  • TNFRSF13C
Reactivity
Human
144
86
32
4
Host
Mouse
88
72
50
Clonality
Monoclonal
Conjugate
This TNFRSF13C antibody is conjugated to FITC
18
12
11
8
7
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
114
75
65
41
37
11
9
7
7
4
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2661625
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008770663 ABIN282575 Func FACS Mouse IgG2a kappa Log in to see 8A7

Top referenced anti-TNFRSF13C antibody for Functional Studies

Similar anti-TNFRSF13C Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 1 Antibodies
ELISA 41 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 67 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 37 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 37 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Intracellular Flow Cytometry (ICFC) 3 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Western Blotting (WB) 59 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Antibodies
Reactivity Human
(144), (86), (32), (4)
Host Mouse
(88), (72), (50)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF13C antibody is conjugated to FITC
(18), (12), (11), (8), (7), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(114), (75), (65), (41), (37), (11), (9), (7), (7), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-TNFRSF13C Antibody

Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone 11C1
Isotype IgG1 kappa

Target Details TNFRSF13C

Product Details anti-TNFRSF13C Antibody Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
Antigen
Alternative Name CD268 (TNFRSF13C Antibody Abstract)
Background B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
Pathways NF-kappaB Signaling

Application Details

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Handling References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details References for anti-TNFRSF13C Antibody (ABIN2661625) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF13C Antibody (ABIN2661625)

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling Images back to top
Background publications

Rodig, Shahsafaei, Li, Mackay, Dorfman: "BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders." in: Human pathology, Vol. 36, Issue 10, pp. 1113-9, 2005

Ye, Wang, Wells, Tao, Han, Davidson, Scott, Hancock: "BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses." in: European journal of immunology, Vol. 34, Issue 10, pp. 2750-9, 2004

Ng, Sutherland, Newton, Qian, Cachero, Scott, Thompson, Wheway, Chtanova, Groom, Sutton, Xin, Tangye, Kalled, Mackay, Mackay: "B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 807-17, 2004

Thompson, Bixler, Qian, Vora, Scott, Cachero, Hession, Schneider, Sizing, Mullen, Strauch, Zafari, Benjamin, Tschopp, Browning, Ambrose: "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF." in: Science (New York, N.Y.), Vol. 293, Issue 5537, pp. 2108-11, 2001

Images

Product Details anti-TNFRSF13C Antibody Target Details TNFRSF13C Application Details Handling References for anti-TNFRSF13C Antibody (ABIN2661625) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF13C antibody (Tumor Necrosis Factor Receptor Superfamily, Member 13C)  (FITC) (ABIN2661625) anti-Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) antibody (FITC)