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anti-Human TNFRSF1A antibody for Radioimmunoassay

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • cd120a
  • CD120a
  • fpf
  • FPF
  • MS5
  • p55
  • p55-R
  • p55-r
  • p60
  • TBP1
  • tbp1
  • TNF-alphaR1
  • TNF-R
  • tnf-r
  • TNF-R-I
  • TNF-R1
  • TNF-R55
  • TNFalpha-R1
  • tnfar
  • TNFAR
  • Tnfr-2
  • tnfr1
  • Tnfr1
  • TNFR1
  • TNFR1-d2
  • tnfr55
  • TNFR55
  • TNFR60
  • tnfr60
  • TNFR I
  • TNFRI
  • TNFRp55
  • TNFRSF1A
  • wu:fj65b10
  • xtnfr1
  • zgc:85914
Reactivity
Human, Rabbit
290
147
79
35
32
29
26
13
9
7
7
6
5
4
4
2
1
1
1
Host
Mouse
253
81
17
16
13
5
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is un-conjugated
31
28
27
13
9
9
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Radioimmunoassay (RIA)
240
136
124
98
97
44
34
33
31
22
22
11
10
9
7
2
2
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN118847
$ 610.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008757905 ABIN2478294 Func FACS RIA ELISA Mouse IgG2a Log in to see H398 4
0.0008757905 ABIN799835 IP RIA ELISA WB Rabbit Extracellular Domain Log in to see Polyclonal
0.0008757905 ABIN209354 FACS IP RIA ELISA WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
0.0008757905 ABIN470640 IP RIA ELISA WB Rabbit IgG Extracellular Domain Log in to see Polyclonal
0.0008757905 ABIN799621 FACS IP RIA ELISA WB Rabbit Log in to see Polyclonal
0.0008757905 ABIN2380425 FACS RIA ELISA WB Mouse IgG2a Log in to see 3H3103
0.0008757905 ABIN2380432 IP RIA ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008757905 ABIN2380431 FACS IP RIA ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008757905 ABIN639333 FACS RIA ELISA Mouse IgG2a Log in to see

Top referenced anti-TNFRSF1A antibody for Radioimmunoassay

Similar anti-TNFRSF1A Antibodies

Application / Reactivity Rabbit Human
ELISA 1 Antibodies 110 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 18 Antibodies
Flow Cytometry (FACS) 7 Antibodies 93 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 18 Antibodies
Immunofluorescence (IF) 18 Antibodies
Immunohistochemistry (IHC) 23 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 21 Antibodies
Radioimmunoassay (RIA) 2 Antibodies
Western Blotting (WB) 29 Antibodies
Agonist (Agon) 1 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Cell Culture (CC) 2 Antibodies
Cytotoxicity Test (CyTox) 1 Antibodies
Dot Blot (DB) 1 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Human, Rabbit
(290), (147), (79), (35), (32), (29), (26), (13), (9), (7), (7), (6), (5), (4), (4), (2), (1), (1), (1)
Host Mouse
(253), (81), (17), (16), (13), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is un-conjugated
(31), (28), (27), (13), (9), (9), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Radioimmunoassay (RIA)
(240), (136), (124), (98), (97), (44), (34), (33), (31), (22), (22), (11), (10), (9), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A Antibody (ABIN118847) Images
Purification Affinity chromatography on Protein A
Immunogen Purified human tumor Necrosis Factor Receptor type 1. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
Clone H398
Isotype IgG2a

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A Antibody (ABIN118847) Images back to top
Antigen
Alternative Name CD120a / TNFR1 (TNFRSF1A Antibody Abstract)
Background Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF Receptor superfamily along with FAS antigen and CD40. TNF Receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 41BB, which are characterized by cysteine rich motifs in the extracellular domain. While TNF Receptor I and TNF Receptor II share 28 % sequence homology in the extracellular domains, their intracellular domains lack sequence homology, suggesting that they differ in their internal signal transduction pathways. TNF Receptor I contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein), and subsequent interactions with FADD. TNF Receptor I can also activate the transcription factor NFkB via TRAF2 (TNF Receptor associated factor 2). The cytoplasmic domain of TNF Receptor I can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade. TNF Receptor I is expressed by virtually all nucleated mammalian cells, including hepatocytes, monocytes and neutrophils, cardiac muscle cells, endothelial cells, and CD34 + hematopoietic progenitors. Both TNF alpha and TNF beta bind to TNF Receptor I.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Gene ID 9606
UniProt P19438
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A Antibody (ABIN118847) Images back to top
Application Notes Flow Cytometry. ELISA. Radioimmunoassay. Removal of sodium azide is recommended prior to use in functional assays. Clone H398 may be used to detect high levels of TNFR1, in western blotting under reducing conditions, such as recombinant material, but it is not suitable for detection of TNFR1 in normal cells in this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A Antibody (ABIN118847) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-TNFRSF1A Antibody (ABIN118847)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Background publications

Dri, Haas, Cramer, Menegazzi, Gasparini, Martinelli, Scheurich, Patriarca: "Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 1, pp. 460-6, 1999

Kohrgruber, Halanek, Gröger, Winter, Rappersberger, Schmitt-Egenolf, Stingl, Maurer: "Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3250-9, 1999

Menegazzi, Cramer, Patriarca, Scheurich, Dri: "Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor." in: Blood, Vol. 84, Issue 1, pp. 287-93, 1994

Thoma, Grell, Pfizenmaier, Scheurich: "Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses." in: The Journal of experimental medicine, Vol. 172, Issue 4, pp. 1019-23, 1990