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anti-Mouse (Murine) TNFRSF1A antibody for Functional Studies

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • cd120a
  • CD120a
  • fpf
  • FPF
  • MS5
  • p55
  • p55-R
  • p55-r
  • p60
  • TBP1
  • tbp1
  • TNF-alphaR1
  • TNF-R
  • tnf-r
  • TNF-R-I
  • TNF-R1
  • TNF-R55
  • TNFalpha-R1
  • tnfar
  • TNFAR
  • Tnfr-2
  • tnfr1
  • Tnfr1
  • TNFR1
  • TNFR1-d2
  • tnfr55
  • TNFR55
  • TNFR60
  • tnfr60
  • TNFR I
  • TNFRI
  • TNFRp55
  • TNFRSF1A
  • wu:fj65b10
  • xtnfr1
  • zgc:85914
Epitope
Extracellular Domain
36
30
15
15
13
13
12
12
11
8
6
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
291
146
79
36
32
29
26
13
9
7
7
6
5
4
4
2
1
1
1
Host
Hamster
253
82
17
15
13
5
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is un-conjugated
31
28
27
13
9
9
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
240
136
125
97
97
44
34
33
31
22
21
11
10
10
7
2
2
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1105788
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087386754 ABIN1105796 Func EIA IP FITC Hamster IgG Extracellular Domain Log in to see 55R-170 4
0.00087386754 ABIN1830498 Func FACS IP ELISA FITC Hamster IgG1 Extracellular Domain Log in to see 13A86
0.00087386754 ABIN1105789 Func EIA IP WB Rabbit IgG Log in to see Polyclonal 3
0.00087386754 ABIN1176998 BR Func Neut Armenian Hamster IgG1 kappa Log in to see 55R-170
0.00087386754 ABIN2191848 Func IA FACS IP FITC Armenian Hamster Log in to see 55R-170 2
0.00087386754 ABIN2192161 Func IA FACS IP WB Rabbit IgG Log in to see Polyclonal 3
0.00087386754 ABIN2192210 Func IA FACS IP Armenian Hamster Log in to see 55R-170 2

Top referenced anti-TNFRSF1A antibody for Functional Studies

Similar anti-TNFRSF1A Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 1 Antibodies
ELISA 20 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 34 Antibodies
Functional Studies (Func) 8 Antibodies
Immunoassay (IA) 3 Antibodies
Immunocytochemistry (ICC) 21 Antibodies
Immunofluorescence (IF) 21 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 45 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 20 Antibodies
Immunoprecipitation (IP) 62 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Neutralization (Neut) 4 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Epitope Extracellular Domain
(36), (30), (15), (15), (13), (13), (12), (12), (11), (8), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(291), (146), (79), (36), (32), (29), (26), (13), (9), (7), (7), (6), (5), (4), (4), (2), (1), (1), (1)
Host Hamster
(253), (82), (17), (15), (13), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is un-conjugated
(31), (28), (27), (13), (9), (9), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
(240), (136), (125), (97), (97), (44), (34), (33), (31), (22), (21), (11), (10), (10), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A Antibody (ABIN1105788) Images
Cross-Reactivity (Details) Species reactivity (tested):Mouse
Purification Purified
Immunogen Purified soluble extracellular domain of mouse TNF-RI
Clone 55R-170
Isotype IgG

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A Antibody (ABIN1105788) Images back to top
Antigen
Alternative Name CD120a / TNFR1 (TNFRSF1A Antibody Abstract)
Background TNF-RI belongs to the large TNF receptor family, among which TNF-RII (TNF-R p75-80), lymphotoxin-beta receptor (LTbetaR) and the Herpes virus entry mediator (HVEM). Ligands for these receptors belong to the Tumor Necrosis Factor (TNF) superfamily of cytokines, which activate signaling pathways for cell survival, death, and differentiation that orchestrate the development, organization and homeostasis of lymphoid, mammary, neuronal and ectodermal tissues. TNF-RI contains a characteristic structural cassette termed death domain in its sequence that is conserved within a distinct subset of other TNF-R family members, such as CD95, DR3, DR4, and DR5. This death domain, was characterized as being essential for induction of apoptosis in vitro and has been structurally conserved within these TNF-R superfamily members. Deletion of the death domain of the TNF-RI results in a non-functional receptor, indicating that the death domain is required for the signal transduction of the physiological functions of TNF-RI in vivo. TNF-RI is a 55 kD type I transmembrane protein and is expressed on a variety of cell types at low levels. It is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is present as soluble form in body fluids (for instance plasma and CSF). This extracellular TNF-RI is generated by two mechanisms, namely proteolytic cleavage of TNF-RI ectodomains and release of full-length TNF-RI in the membranes of exosome-like vesicles. TNF-RI and TNF-RII both interact with the homomeric forms of LTbeta or TNF. However, TNF-RI functions as the high affinity receptor for soluble TNF (sTNF). TNF-RI has been shown to be involved in a wide variety of inflammatory diseases, among which neurodegenerative diseases (Parkinson's and Alzheimer's disease), multiple sclerosis, asthma, atherosclerosis, rheumatology.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
UniProt P25118
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A Antibody (ABIN1105788) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A Antibody (ABIN1105788) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 1 % bovine serum albumin
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-TNFRSF1A Antibody (ABIN1105788)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Background publications

Lee, Park, Yoo, Choi, Sung: "Inhibition of TCR-induced CD8 T cell death by IL-12: regulation of Fas ligand and cellular FLIP expression and caspase activation by IL-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 5, pp. 2456-60, 2003

Ji, Pettit, Ohmura, Ortiz-Lopez, Duchatelle, Degott, Gravallese, Mathis, Benoist: "Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis." in: The Journal of experimental medicine, Vol. 196, Issue 1, pp. 77-85, 2002

Pinckard, Sheehan, Schreiber: "Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells." in: The Journal of biological chemistry, Vol. 272, Issue 16, pp. 10784-9, 1997

Sheehan, Pinckard, Arthur, Dehner, Goeddel, Schreiber: "Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75." in: The Journal of experimental medicine, Vol. 181, Issue 2, pp. 607-17, 1995