anti-Mouse (Murine) TNFRSF1A antibody for Immunohistochemistry (Frozen Sections)

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • fpf
  • p55
  • tbp1
  • p55-r
  • tnf-r
  • tnfar
  • tnfr1
  • cd120a
  • tnfr55
  • tnfr60
  • xtnfr1
  • TNFR I
  • TNFRSF1A
  • TNFR1
  • CD120a
  • FPF
  • MS5
  • TBP1
  • TNF-R
  • TNF-R-I
  • TNF-R55
  • TNFAR
  • TNFR1-d2
  • TNFR55
  • TNFR60
  • p55-R
  • p60
  • TNF-R1
  • TNF-alphaR1
  • TNFRI
  • TNFRp55
  • TNFalpha-R1
  • Tnfr-2
  • Tnfr1
  • wu:fj65b10
  • zgc:85914
  • tumor necrosis factor receptor superfamily, member 1A
  • tumor necrosis factor receptor superfamily, member 1a
  • tnfrsf1a
  • TNFRSF1A
  • Tnfrsf1a
Reactivity
Mouse (Murine)
406
185
112
61
55
52
47
16
14
9
9
8
8
4
3
2
1
1
Host
Rat
264
161
22
19
16
14
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is conjugated to FITC
33
28
27
14
12
10
9
8
8
8
8
6
6
6
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
304
205
149
114
109
84
45
43
32
22
22
22
13
11
7
7
7
5
4
2
2
2
2
1
1
1
1
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Catalog No. ABIN1105797
$ 654.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1105791 EIA IHC (fro) FACS IP Rat IgG2a Log in to see HM104 3
1 ABIN602487 IHC (fro) FACS IP ELISA Rat IgG2a Log in to see HM104
1 ABIN602491 IHC (fro) FACS IHC (p) FITC Rat IgG2a Log in to see
1 ABIN215522 FACS IHC (fro) IP Biotin Rat IgG2a Log in to see
1 ABIN959777 IHC (fro) FACS IP ELISA Rat IgG2a Log in to see HM14

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Mouse (Murine)
(406), (185), (112), (61), (55), (52), (47), (16), (14), (9), (9), (8), (8), (4), (3), (2), (1), (1)
Host Rat
(264), (161), (22), (19), (16), (14), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is conjugated to FITC
(33), (28), (27), (14), (12), (10), (9), (8), (8), (8), (8), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
(304), (205), (149), (114), (109), (84), (45), (43), (32), (22), (22), (22), (13), (11), (7), (7), (7), (5), (4), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A antibody (ABIN1105797) Images
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Protein G
Clone HM104
Isotype IgG2a

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A antibody (ABIN1105797) Images back to top
Antigen
Alternative Name CD120a / TNFR1 (TNFRSF1A Antibody Abstract)
Background TNF-RI (~55-60 kDa) is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-alpha activates inflammatory responses, induces apoptosis, regulates cellular proliferation, and may even promote cancer progression. The effects of TNF-alpha are mediated by TNF-RI and TNF-RII, which have both distinct and overlapping downstream signaling cascades. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membrane-bound form, whereas TNF-RII is efficiently activated only by the membrane bound form of TNF-alpha. TNF-RI signaling is initiated when trimeric TNF-alpha binds TNF-RI receptors. Subsequent TNF-RI trimerization promotes the recruitment of a proximal signaling complex composed of TNF Receptor Associated protein with a Death Domain (TRADD), Receptor Interacting Protein (RIP), cellular Inhibitor of Apoptosis Protein 1 (cIAP1), TNF Receptor Associated Factor 2 (TRAF2), and likely TRAF5. Studies with TNF-RI-deficient mice indicate that TNF-RI mediates most of the proliferation, pro-inflammatory, and apoptosis-activating pathways.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Gene ID 10090
UniProt P25118
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A antibody (ABIN1105797) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A antibody (ABIN1105797) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % Sodium Azide, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
Expiry Date 6 months

References for anti-TNFRSF1A antibody (ABIN1105797)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Background publications

Bigini, Mennini: "Immunohistochemical localization of TNFalpha and its receptors in the rodent central nervous system." in: Methods in molecular medicine, Vol. 98, pp. 73-80, 2004

Ghezzi, Cerami: "Tumor necrosis factor as a pharmacological target." in: Methods in molecular medicine, Vol. 98, pp. 1-8, 2004

Mennini, Bigini, Cagnotto, Carvelli, Di Nunno, Fumagalli, Tortarolo, Buurman, Ghezzi, Bendotti: "Glial activation and TNFR-I upregulation precedes motor dysfunction in the spinal cord of mnd mice." in: Cytokine, Vol. 25, Issue 3, pp. 127-35, 2003