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anti-Mouse (Murine) TNFRSF1B antibody for Immunoassay

Recommended TNFRSF1B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies
  • MGC83471
  • LOC100218184
  • TRAF2
  • TANK
  • TNF-RII/TNFRSF1B
  • TNFRSF1B
  • CD120b
  • TBPII
  • TNF-R-II
  • TNF-R75
  • TNFBR
  • TNFR1B
  • TNFR2
  • TNFR80
  • p75
  • p75TNFR
  • TNF-R2
  • TNF-alphaR2
  • TNFRII
  • TNFalpha-R2
  • Tnfr-1
  • Tnfr2
  • TNFR-II
  • TNF receptor-associated factor 2
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase
  • TNF receptor-associated factor 3
  • TRAF family member-associated NFKB activator
  • tumor necrosis factor receptor superfamily, member 1B
  • tumor necrosis factor receptor superfamily, member 1b
  • TRAF2
  • traf2
  • TRAF6
  • LOC100218184
  • LOC100359083
  • TANK
  • TNFRSF1B
  • LOC100222629
  • Tnfrsf1b
Reactivity
Mouse (Murine)
162
105
35
3
1
Host
Rat
118
69
17
15
15
12
1
Clonality
Monoclonal
Conjugate
This TNFRSF1B antibody is conjugated to Biotin
26
12
10
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
150
93
86
50
37
29
26
26
19
19
10
8
5
3
2
2
1
1
1
1
1
Options
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Catalog No. ABIN2191752
$ 455.24
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2191751 Func IA FACS IP WB FITC Rat Log in to see HM102 2
1 ABIN2191750 Func IA FACS IP WB Rat Log in to see HM102 2
1 ABIN2192162 Func IA FACS IP WB Rabbit IgG Log in to see Polyclonal 3

Top referenced anti-TNFRSF1B antibody for Immunoassay

Similar anti-TNFRSF1B Antibodies

Application / Reactivity Mouse (Murine)
Cytometry by Time of Flight (CyTOF) 1 Antibodies
ELISA 37 Antibodies
ELISA (Capture) 3 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 43 Antibodies
Functional Studies (Func) 9 Antibodies
Immunoassay (IA) 4 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 28 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Neutralization (Neut) 2 Antibodies
Western Blotting (WB) 70 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies
Reactivity Mouse (Murine)
(162), (105), (35), (3), (1)
Host Rat
(118), (69), (17), (15), (15), (12), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1B antibody is conjugated to Biotin
(26), (12), (10), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(150), (93), (86), (50), (37), (29), (26), (26), (19), (19), (10), (8), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-TNFRSF1B Antibody

Target Details TNFRSF1B Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2191752) Images
Sterility 0.2 μm filtered
Clone HM102

Target Details TNFRSF1B

Product Details anti-TNFRSF1B Antibody Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2191752) Images back to top
Antigen
Alternative Name Tnf-Rii (TNFRSF1B Antibody Abstract)
Background The monoclonal antibody HM102 recognizes the extracellular part of membrane-bound TNF-RII as well as the soluble form of TNF-RII which is generated by proteolytic cleavage of the extracellular domain. The soluble form can still bind TNF-alpha with high affinity and functions as a TNF-alpha antagonist. TNF-alpha is an important signalling protein in the immune system which can activate inflammatory responses, induce apoptosis, regulate cellular proliferation, and may even promote cancer progression. TNF-alpha can bind to two structurally distinct membrane receptors, TNF-RI and TNFRII, which have both distinct and overlapping downstream signaling cascades. TNFRI is believed to be expressed on nearly all cell types, whereas TNFRII exhibits more restricted expression, being found on certain subpopulations of immune cells and several other cell types. A dominant role of TNFRII has been shown in thymocyte activation by TNF-alpha, whereas induction of cytotoxicity and other functions are mediated largely by TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membrane-bound form, whereas TNF-RII is activated only by the membrane bound form of TNF-alpha. The antibody is a non-agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII. Aliases Tumor necrosis factor receptor superfamily member 1B, CD120b, TNF-R2, p75, p80 TNF-alpha receptor
Pathways NF-kappaB Signaling, Apoptosis

Application Details

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Handling References for anti-TNFRSF1B Antibody (ABIN2191752) Images back to top
Application Notes For immunohistochemistry, flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Positive RAW264.7 cells control
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details References for anti-TNFRSF1B Antibody (ABIN2191752) Images back to top
Buffer PBS, containing 0.1 % bovine serum albumin.
Storage 4 °C
Storage Comment Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

References for anti-TNFRSF1B Antibody (ABIN2191752)

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling Images back to top
Product cited in:

Brekke, Sagen, Bjerve: "Specificity of endogenous fatty acid release during tumor necrosis factor-induced apoptosis in WEHI 164 fibrosarcoma cells." in: Journal of lipid research, Vol. 40, Issue 12, pp. 2223-33, 2000

Tacchini-Cottier, Vesin, Redard, Buurman, Piguet: "Role of TNFR1 and TNFR2 in TNF-induced platelet consumption in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 12, pp. 6182-6, 1998

Images

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2191752) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF1B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 1B)  (Biotin) (ABIN2191752) Flow cytometric detection of mouse TNF-RII (5µg/ml) on 500,000 BV2 microglial cells (...