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|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TNFRSF1B antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-TNFRSF1B AntibodyTarget Details TNFRSF1B Application Details Handling Images
|Specificity||This antibody recognizes the C-term of TNFRSF1B / TNFR2.|
Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.
|Immunogen||Synthetic peptide derived from C-terminal of Mouse TNF-R2|
Target Details TNFRSF1BProduct Details anti-TNFRSF1B Antibody Application Details Handling Images back to top
|Alternative Name||CD120b / TNFR2 (TNFRSF1B Antibody Abstract)|
|Background||TNFR2 is a 75 kD transmembrane glycoprotein that also exists as a secreted protein. TNF receptors self assemble through a distinct functional extracellular domain termed PLAD in the absence of ligand. Efficient TNFA binding depends on receptor self assembly. TNFR2 has been shown to be responsible for stimulation of activated T lymphocytes by TNFalpha.Synonyms: TNF-R2, TNFBR, TNFRSF1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor type II, p80 TNF-alpha receptor|
|Research Area||CD Antigens, Surface Receptors of Immune Cells|
|Pathways||NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C|
Application DetailsProduct Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Handling Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Images back to top
|Buffer||10 mM PBS, pH 7.4, Less that 0.1 % Sodium Azide, BSA|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!|
ImagesProduct Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling back to top