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anti-Mouse (Murine) TNFRSF1B antibody for Neutralization

Recommended TNFRSF1B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies
  • CD120b
  • LOC100218184
  • MGC83471
  • p75
  • p75TNFR
  • TANK
  • TBPII
  • TNF-alphaR2
  • TNF-R-II
  • TNF-R2
  • TNF-R75
  • TNF-RII/TNFRSF1B
  • TNFalpha-R2
  • TNFBR
  • Tnfr-1
  • TNFR-II
  • TNFR1B
  • Tnfr2
  • TNFR2
  • TNFR80
  • TNFRII
  • TNFRSF1B
  • TRAF2
Reactivity
Mouse (Murine)
156
104
34
3
1
Host
Hamster
121
63
17
13
13
12
1
Clonality
Monoclonal
Conjugate
This TNFRSF1B antibody is conjugated to PE
27
12
7
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA (Capture), Neutralization (Neut)
155
94
85
61
36
32
30
28
19
19
9
9
3
2
2
1
1
1
1
1
Supplier
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Available images

Catalog No. ABIN2662981
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008737065 ABIN2662982 ELISA (Capture) Neut PE Hamster IgG Log in to see TR75-89 7

Top referenced anti-TNFRSF1B antibody for Neutralization

Similar anti-TNFRSF1B Antibodies

Application / Reactivity Mouse (Murine)
ELISA 43 Antibodies
ELISA (Capture) 2 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 41 Antibodies
Functional Studies (Func) 10 Antibodies
Immunoassay (IA) 4 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 40 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies
Neutralization (Neut) 2 Antibodies
Western Blotting (WB) 74 Antibodies

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies
Reactivity Mouse (Murine)
(156), (104), (34), (3), (1)
Host Hamster
(121), (63), (17), (13), (13), (12), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1B antibody is conjugated to PE
(27), (12), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture), Neutralization (Neut)
(155), (94), (85), (61), (36), (32), (30), (28), (19), (19), (9), (9), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-TNFRSF1B Antibody

Target Details TNFRSF1B Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2662981) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone TR75-89
Isotype IgG

Target Details TNFRSF1B

Product Details anti-TNFRSF1B Antibody Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2662981) Images back to top
Antigen
Alternative Name CD120b (TNFRSF1B Antibody Abstract)
Background CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Pathways NF-kappaB Signaling, Apoptosis

Application Details

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Handling References for anti-TNFRSF1B Antibody (ABIN2662981) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details References for anti-TNFRSF1B Antibody (ABIN2662981) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF1B Antibody (ABIN2662981)

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling Images back to top
Background publications

Bell, Herrera, Li, Walcheck: "Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages." in: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 173-6, 2007

Schlaepfer, Hou, Lim, Tomar, Yu, Lim, Hanson, Uryu, Molina, Mitra: "Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression." in: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17450-9, 2007

Chan, Chun, Zheng, Siegel, Bui, Lenardo: "A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling." in: Science (New York, N.Y.), Vol. 288, Issue 5475, pp. 2351-4, 2000

Sheehan, Pinckard, Arthur, Dehner, Goeddel, Schreiber: "Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75." in: The Journal of experimental medicine, Vol. 181, Issue 2, pp. 607-17, 1995

Rothe, Lesslauer, Lötscher, Lang, Koebel, Köntgen, Althage, Zinkernagel, Steinmetz, Bluethmann: "Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes." in: Nature, Vol. 364, Issue 6440, pp. 798-802, 1993

Loetscher, Pan, Lahm, Gentz, Brockhaus, Tabuchi, Lesslauer: "Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor." in: Cell, Vol. 61, Issue 2, pp. 351-9, 1990

Aggarwal, Eessalu, Hass: "Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon." in: Nature, Vol. 318, Issue 6047, pp. 665-7, 1986

Images

Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling References for anti-TNFRSF1B Antibody (ABIN2662981) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-TNFRSF1B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 1B)  (PE) (ABIN2662981) anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) antibody (PE)