Browse our TNFRSF1B Proteins (TNFRSF1B)

Full name:
Tumor Necrosis Factor Receptor Superfamily, Member 1B Proteins (TNFRSF1B)
On are 43 Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Proteins from 14 different suppliers available. Additionally we are shipping TNFRSF1B Antibodies (292) and TNFRSF1B Kits (51) and many more products for this protein. A total of 408 TNFRSF1B products are currently listed.
CD120b, LOC100218184, MGC83471, p75, p75TNFR, TANK, TBPII, TNF-alphaR2, TNF-R-II, TNF-R2, TNF-R75, TNF-RII/TNFRSF1B, TNFalpha-R2, TNFBR, Tnfr-1, TNFR-II, TNFR1B, Tnfr2, TNFR80, TNFRII, TNFRSF1B, TRAF2
list all proteins Gene Name GeneID UniProt
TNFRSF1B 7133 P20333
TNFRSF1B 21938 P25119
TNFRSF1B 156767 Q80WY6

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TNFRSF1B Proteins (TNFRSF1B) by Origin

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Top referenced TNFRSF1B Proteins

  1. Mouse (Murine) TNFRSF1B Protein expressed in Human Cells - ABIN2007373 : Wassink, Crowe, Andreasen: Tumor necrosis factor receptor-II: heritability and effect on brain morphology in schizophrenia. in Molecular psychiatry 2000 (PubMed)
    Show all 3 references for 2007373

  2. Human TNFRSF1B Protein expressed in Human Cells - ABIN2002807 : Chung, Guan, Yuan, Albina, Chin: Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II. in Molecular and cellular biology 2005 (PubMed)
    Show all 3 references for 2002807

  3. Human TNFRSF1B Protein expressed in HEK-293 Cells - ABIN2181842 : Ziegenhagen, Fitschen, Martinet, Schlaak, Müller-Quernheim: Serum level of soluble tumour necrosis factor receptor II (75 kDa) indicates inflammatory activity of sarcoidosis. in Journal of internal medicine 2000 (PubMed)
    Show all 3 references for 2181842

  4. Cynomolgus TNFRSF1B Protein expressed in Human Cells - ABIN2009844 : Nozar, Philippe, Fabrice, Silvia, Marc: Acute pure spontaneous subdural haematoma from ruptured intracranial aneurysms. in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2010 (PubMed)
    Show all 2 references for 2009844

More Proteins for TNFRSF1B Interaction Partners

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

  1. These results show an unclear effect of considered T>C polymorphism on TNF-RII gene expression in bovine leukocytes and they suggest the involvement of BLV in modifying the TNF-RII expression in BLV-infected cows.

  2. These results suggest that the endometrium might lower the TNF (show TNF Proteins) concentration in the blastocyst by (1) regulating TNF (show TNF Proteins) secretion into the uterine fluid and (2) inducing decreased TNF (show TNF Proteins) and TNFR2 mRNA transcription in the embryo.

  3. These results suggest that TNF-alpha (show TNF Proteins) sources include immune cells, as well as large and small luteal cells, and that TNF-RI (show TNFRSF1A Proteins) and TNF-RII are present in the luteal cells of the bovine corpus luteum.

  4. The expression and cellular localization of tumor necrosis factor-alpha (TNF (show TNF Proteins)) and its receptors (TNFRI (show TNFRSF1A Proteins) and TNFRII) mRNAs and proteins, were determined.[TNFRII]

Human Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

  1. Serum TNFR2 levels were elevated in lupus nephritis patients versus controls.

  2. Adalimumab bound to monocyte membrane TNF (show TNF Proteins) from rheumatoid arthritis patients and unexpectedly enhanced its expression and its binding to TNF-RII expressed on T reg (show EXTL3 Proteins) cells.

  3. Voxel-based morphometry was used to analyse the associations between TNFRSF1B (rs1061624) genotypes and grey matter structure. Analysis of the TNFRSF1B SNP rs1061624 yielded a significant association with hippocampal but not with striatal volume, whereby G homozygotes were associated with increased volumes relative to A homozygotes and heterozygotes.

  4. Circulating TNFR1 (show TNFRSF1A Proteins) and 2 were shown to be associated with cardiovascular disease, independent of age, sex, inflammatory markers, and other cardiovascular disease risk factors, in the chronic kidney disease patients

  5. Data suggest that TRAF2 (TNF receptor-associated factor 2 (show TRAF2 Proteins)) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (show TNFRSF1A Proteins))-induced apoptosis, (2) TNFR2- (tumor necrosis factor (show TNF Proteins) receptor type 2)-induced non-canonical NFkappaB (show NFKB1 Proteins) signaling, and (3) TNF- (tumor necrosis factor (show TNF Proteins))-induced necroptosis. [REVIEW]

  6. Our results demonstrated that Treg frequencies and TNFR2 expression on Tregs are increased in sarcoidosis, followed by a decline during infliximab therapy, suggesting a pathophysiological role of this T cell subset.

  7. Data indicate that plasma concentrations of TNFR1 (show TNFRSF1A Proteins) and TNFR2 are elevated in pediatric lupus nephritis.

  8. TNFR1 is the major pro-inflammatory mediator of TNF-alpha in fibroblast-like synoviocytes (FLS), whereas TNFR2, may act as an immunosuppressor in FLS for the prevention of overwhelming inflammatory reactions.

  9. identified 6 known and 4 novel variations in 6 different exons of TNFR2 gene; out of these identified variations, 5 known variations were found to be significantly associated with the risk of cervical cancer; postmenopausal women having CAAGC + CTGCC haplotypes in TNFR2 gene along with HPV infection and tobacco consumption may lead to the development of cervical cancer

  10. LTbetaR is essential for efficient liver regeneration and cooperates with TNFRp55 (show TNFRSF1A Proteins) in this process. Differences in survival kinetics strongly suggest distinct functions for these two cytokine receptors in liver regeneration.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

  1. study reports an important role for TNFR2 on low-affinity-primed secondary effector CD8 (show CD8A Proteins)+ T cells; results demonstrate the importance of TNF (show TNF Proteins) signaling in low-affinity, cross-reactive CD8 (show CD8A Proteins)+ T cell responses during heterologous immunity

  2. TNF (show TNF Proteins) plays an inhibitory role in modulating myocardial SDF-1 (show CXCL12 Proteins) production and blockade of TNF (show TNF Proteins) signaling by ablation of TNFR1 (show TNFRSF1A Proteins) and TNFR2 genes increased SDF-1 (show CXCL12 Proteins) expression in the heart. These data expand on TNF (show TNF Proteins) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 (show CXCL12 Proteins) and TNFR (show TNFRSF1A Proteins)-derived actions in hopes of advancing ischemic heart injury treatments.

  3. Results suggest that elevated TNF (show TNF Proteins) in the heart, via TNFR1 (show TNFRSF1A Proteins) and TNFR2, restrains cardiomyocyte differentiation of resident cardiac stem cells and may enhance adrenergic activation, both effects that would reduce the effectiveness of endogenous cardiac repair and the response to exogenous stem cell therapy, while promoting adverse cardiac remodeling.

  4. Report chronic inflammatory multiorgan hepatobiliary pancreatitis, along with fibrosis and calculi formation induced by oral dibutyltin administration in TNFR1 (show TNFRSF1A Proteins)/R2 deficient mice.

  5. These findings implicate TNF (show TNF Proteins)-receptor signaling cascades in the regulation of homeostatic plasticity of denervated networks and suggest an important role for TNFalpha (show TNF Proteins)-signaling in the course of neurological diseases accompanied by deafferentation.

  6. TNF (show TNF Proteins) receptor 1 (TnfR1 (show TNFRSF1A Proteins)) signaling is believed to be a major mediator of the cytotoxicity of Tnf-a (show TNF Proteins) through activation of caspases.

  7. our findings implicate TNFR2 in supporting myeloid-derived suppressor cells -mediated immune suppression and metastasis in the liver

  8. TNFR2 blockade appears to disrupt commensal bacteria-host immune symbiosis to reveal autoimmune demyelination in genetically susceptible mice.

  9. TNFR2 protects mice from colitis by inhibiting the expansion of colonic CD8 (show CD8A Proteins)(+) T cells.

  10. Collectively, these results demonstrate that TNFR2-bearing CD8 (show CD8A Proteins)(+) T cells and TNFR1 (show TNFRSF1A Proteins)-bearing non-CD8 (show CD8A Proteins)(+) T cells contribute significantly to oviduct pathology following genital chlamydial infection.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

  1. Retinal ischemia results in increased expression of TNF-alpha (show TNF Proteins) and its receptors (TNF-R1 (show TNFRSF1A Proteins) and TNF-R2).

  2. Porcine TNFR2 (1,125 bp, 375 amino acid residues), which contains specific amino acid region of transmembrane, indicated high identities with human and murine TNFR2

TNFRSF1B Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Alternative names and synonyms associated with TNFRSF1B

  • TNF receptor-associated factor 2 (TRAF2)
  • TNF receptor-associated factor 2 (traf2)
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6)
  • TNF receptor-associated factor 3 (LOC100218184)
  • TNF receptor-associated factor 3 (LOC100359083)
  • TRAF family member-associated NFKB activator (TANK)
  • tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B)
  • tumor necrosis factor receptor superfamily, member 1B (LOC100222629)
  • tumor necrosis factor receptor superfamily, member 1b (Tnfrsf1b)
  • tumor necrosis factor receptor superfamily, member 1B (Tnfrsf1b)
  • CD120b protein
  • LOC100218184 protein
  • MGC83471 protein
  • p75 protein
  • p75TNFR protein
  • TANK protein
  • TBPII protein
  • TNF-alphaR2 protein
  • TNF-R-II protein
  • TNF-R2 protein
  • TNF-R75 protein
  • TNF-RII/TNFRSF1B protein
  • TNFalpha-R2 protein
  • TNFBR protein
  • Tnfr-1 protein
  • TNFR-II protein
  • TNFR1B protein
  • Tnfr2 protein
  • TNFR80 protein
  • TNFRII protein
  • TNFRSF1B protein
  • TRAF2 protein

Protein level used designations for TNFRSF1B

TNF receptor-associated factor 2 , E3 ubiquitin-protein ligase TRAF6 , TNF receptor-associated factor 6 , TNF receptor-associated factor 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2-like , tumor necrosis factor receptor superfamily member 1B , tumor necrosis factor receptor 2 , tumor necrosis factor receptor superfamily, member 1B , TNF-R2 , TNF-RII , p75 TNF receptor , p80 TNF-alpha receptor , soluble TNFR1B variant 1 , tumor necrosis factor beta receptor , tumor necrosis factor binding protein 2 , tumor necrosis factor receptor type II , TNF receptor beta chain , TNFR-II , p75 TNFR , p75 , tumor necrosis factor receptor-II

417287 Gallus gallus
431974 Xenopus laevis
716907 Macaca mulatta
100218184 Taeniopygia guttata
100359083 Oryctolagus cuniculus
100404226 Callithrix jacchus
100458089 Pongo abelii
100474087 Ailuropoda melanoleuca
100590721 Nomascus leucogenys
338033 Bos taurus
457968 Pan troglodytes
487437 Canis lupus familiaris
715454 Macaca mulatta
100222629 Taeniopygia guttata
100240715 Ovis aries
7133 Homo sapiens
21938 Mus musculus
156767 Rattus norvegicus
100037306 Sus scrofa
395083 Gallus gallus
100723273 Cavia porcellus
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