anti-Dog (Canine) TRADD antibody for Western Blotting

Recommended TRADD Antibody (supplied by: Log in to see )

Antigen
TNFRSF1A-Associated Via Death Domain (TRADD) Antibodies
  • TRADD
  • Hs.89862
  • 9130005N23Rik
  • AA930854
  • wu:fc59e02
  • zgc:103556
  • tradd
  • TNFRSF1A-associated via death domain
  • conjugal transfer protein D
  • tnfrsf1a-associated via death domain
  • tnfrsf1a-associated via death domain protein
  • TRADD
  • LOC100337888
  • traDd
  • Tradd
  • tradd
  • LOC100136668
Epitope
Middle Region
19
16
10
10
9
8
5
5
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human
119
38
27
5
4
3
3
1
Host
Rabbit
97
32
Clonality
Polyclonal
Conjugate
This TRADD antibody is un-conjugated
5
5
3
3
3
3
3
3
3
2
2
2
2
Application
Western Blotting (WB)
103
56
44
43
30
27
19
11
5
2
1
1
1
1
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Catalog No. ABIN2792121
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN2705304 IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN926870 WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN470367 WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2745114 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2972269 IHC WB Rabbit C-Term Log in to see Polyclonal

General

Antigen TNFRSF1A-Associated Via Death Domain (TRADD) Antibodies
Epitope Middle Region
(19), (16), (10), (10), (9), (8), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Horse (Equine), Human
(119), (38), (27), (5), (4), (3), (3), (1)
Host Rabbit
(97), (32)
Clonality
Polyclonal
Conjugate This TRADD antibody is un-conjugated
(5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Application Western Blotting (WB)
(103), (56), (44), (43), (30), (27), (19), (11), (5), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-TRADD Antibody

Target Details TRADD Application Details Handling References for anti-TRADD antibody (ABIN2792121) Images
Sequence YEQAFQLLRR FVQAEGRRAT LQRLVEALEE NELTSLAEDL LGLTDPNGGL
Predicted Reactivity Dog: 76%, Horse: 76%, Human: 100%
Characteristics This is a rabbit polyclonal antibody against TRADD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human TRADD

Target Details TRADD

Product Details anti-TRADD Antibody Application Details Handling References for anti-TRADD antibody (ABIN2792121) Images back to top
Antigen
Alternative Name TRADD (TRADD Antibody Abstract)
Background TRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hs.89862, MGC11078
Protein Interaction Partner: FADD, UBC, TNF, RIPK1, TNFRSF1A, ZMYND11, TOMM70A, PDLIM7, LRRK2, OPTN, TRADD, TRAF2, TRAF1, TNFRSF1B, GFRA1, CHUK, FAS, DAB2IP, EDAR, CDKN2A, TRIP12, LMP1, CASP8, SH3KBP1, USP2, TNFRSF25, PPP2R1A, TRPC4AP, HIPK2, TNFRSF21, CNTRL, TNFRSF10B, TNFRSF10A, BC
Protein Size: 312
Molecular Weight 34 kDa
Gene ID 8717
NCBI Accession NM_003789, NP_003780
UniProt Q15628
Research Area Cardiovascular, Atherosclerosis, Apoptosis/Necrosis
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C

Application Details

Product Details anti-TRADD Antibody Target Details TRADD Handling References for anti-TRADD antibody (ABIN2792121) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 312 AA

Restrictions For Research Use only

Handling

Product Details anti-TRADD Antibody Target Details TRADD Application Details References for anti-TRADD antibody (ABIN2792121) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRADD antibody (ABIN2792121)

Product Details anti-TRADD Antibody Target Details TRADD Application Details Handling Images back to top
Background publications

Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: "Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus." in: Rheumatology (Oxford, England), Vol. 47, Issue 2, pp. 158-64, 2008

Images

Product Details anti-TRADD Antibody Target Details TRADD Application Details Handling References for anti-TRADD antibody (ABIN2792121) back to top
Supplier Images
Western Blotting (WB) image for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (Middle Region) antibody (ABIN2792121) WB Suggested Anti-TRADD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: