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anti-Human TRAF1 Antibodies:
anti-Mouse (Murine) TRAF1 Antibodies:
anti-Rat (Rattus) TRAF1 Antibodies:
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Cow (Bovine) Polyclonal TRAF1 Primary Antibody for WB - ABIN2792210
Palomino-Morales, Rojas-Villarraga, González, Ramírez, Anaya, Martín: STAT4 but not TRAF1/C5 variants influence the risk of developing rheumatoid arthritis and systemic lupus erythematosus in Colombians. in Genes and immunity 2008
Human Polyclonal TRAF1 Primary Antibody for IF (p), IHC (p) - ABIN673464
Wang, Luo, Pan, Huang, Lv, Guo, Xu, Shen: Comparative genomic study of gastric epithelial cells co-cultured with Helicobacter pylori. in World journal of gastroenterology : WJG 2013
Human Polyclonal TRAF1 Primary Antibody for WB - ABIN374661
Su, Li, Meng, Qian, Xie, Chen, Zhai, Shu: TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling. in European journal of immunology 2006
Traf4 is expressed throughout development, and is required for efficient apical constrictions of ventral furrow cells.
Expression of Reaper leads to a loss of DIAP1 (show DIAPH1 Antibodies) inhibition of DTRAF1-mediated JNK (show MAPK8 Antibodies) activation in Drosophila cells.
DTRAF1-null mutant showed a remarkable reduction in JNK (show MAPK8 Antibodies) activity with an impaired development of imaginal discs and a defective formation of photosensory neuron arrays.
Data suggest that, during B-cell transformation by Epstein-Barr virus, LMP1 (show PDLIM7 Antibodies) (EBV latent membrane protein 1) induces signaling that stimulates Lys63-polyubiquitin (show UBB Antibodies) chain attachment to TRAF1 (TNF receptor-associated factor 1) in the B-lymphocytes.
This study did not replicate the association between PTPRC (show PTPRC Antibodies) and the response to anti-TNF (show TNF Antibodies) treatment in our Southern European population. We found that TRAF1/C5 risk RA variants potentially influence anti-TNF (show TNF Antibodies) treatment response.
Rs2900180 in C5-TRAF1 and linked variants in a 66Kb region were associated with radiographic progression in ACPA (show PRTN3 Antibodies)-negative RA
TRAF1/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population.
TRAF1-ALK (show ALK Antibodies) translocation contributes to neoplastic phenotype in anaplastic large-cell lymphoma.
DNMT3L (show TRDMT1 Antibodies) can address DNMT3A (show DNMT3A Antibodies)/B to specific sites by directly interacting with TFs that do not directly interact with DNMT3A (show DNMT3A Antibodies)/B
These findings suggest that the rs0818488 in TRAF1/C5 region is not associated with rheumatoid arthritis in Iranian population.
Genetic polymorphism rs10818488 in TRAF1/C5 gene might be associated with rheumatoid arthritis susceptibility. [Meta-analysis]
Single nucleotide polymorphism of TRAF1 predicts the clinical response to anti-TNF (show TNF Antibodies) treatment in Japanese patients with rheumatoid arthritis.
The association between rs2900180 and rs3761847 polymorphisms and quality of life variables indicates that TRAF1 is involved in the induction of impaired quality of life in primary biliary cirrhosis.
NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1), TNF receptor-associated factor 2 (TRAF2 (show TRAF2 Antibodies)), cellular inhibitor of apoptosis (cIAP2 (show BIRC3 Antibodies)), and Ferritin heavy chain (FTH1 (show FTH1 Antibodies)) were increased following Losartan treatment
TRAF1 is a crucial early mediator of hepatic ischemia/reperfusion injury.
Increased neuronal TRAF1 leads to elevated neuronal death and enlarged ischaemic lesions.
The pathogenesis of spontaneous KRN/I-A(g7) arthritis can largely proceed by TRAF1-independent pathways.
Together, these findings define the importance of the basal phosphorylation state of the TRAF1 Serine 139 residue in coordinating signalling events downstream of 4-1BB (show TNFRSF9 Antibodies) in primary T cells.
TRAF1 and LSP1 (show LSP1 Antibodies) cooperate downstream of 4-1BB (show TNFRSF9 Antibodies) to activate ERK (show EPHB2 Antibodies) signaling and down-modulate the levels of Bim (show BCL2L11 Antibodies) leading to enhanced T cell survival.
TRAF1 plays a critical role in regulating T cell activation both through restricting the costimulation independent activation of NIK (show MAP4K4 Antibodies) in activated T cells and by promoting the 4-1BB (show TNFRSF9 Antibodies)-induced classical NF-kappaB (show NFKB1 Antibodies) pathway.
These findings identify TRAF1 as a potential biomarker of HIV-specific CD8 (show CD8A Antibodies) T cell fitness during the chronic phase of disease and a target for therapy.
combined signaling from the TNF (show TNF Antibodies) or IL-1 (show IL1A Antibodies) receptors promotes maximal lung inflammation that may contribute to the severity of disease caused by H5N1 virus infection
TRAF1 deficiency attenuates atherogenesis in mice, most likely owing to impaired monocyte recruitment to the vessel wall
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins\; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
, TNF receptor associated factor 1
, TNF-receptor-associated factor 1
, Epstein-Barr virus-induced protein 6
, TNF receptor-associated factor 1
, TNF receptor-associated factor 1-like
, Epstein-Bar virus-induced protein 6