Browse our anti-TRAF2 (TRAF2) Antibodies

Full name:
anti-TNF Receptor-Associated Factor 2 Antibodies (TRAF2)
On are 200 TNF Receptor-Associated Factor 2 (TRAF2) Antibodies from 28 different suppliers available. Additionally we are shipping TRAF2 Proteins (9) and many more products for this protein. A total of 234 TRAF2 products are currently listed.
AI325259, MGC:45012, TANK, TRAP, TRAP3
list all antibodies Gene Name GeneID UniProt
TRAF2 7186 Q12933
TRAF2 22030 P39429
TRAF2 311786  

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anti-Human TRAF2 Antibodies:

anti-Mouse (Murine) TRAF2 Antibodies:

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Top referenced anti-TRAF2 Antibodies

  1. Human Monoclonal TRAF2 Primary Antibody for WB - ABIN967631 : Arch, Gedrich, Thompson: Translocation of TRAF proteins regulates apoptotic threshold of cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 7 references for 967631

  2. Human Monoclonal TRAF2 Primary Antibody for IHC (p), IHC - ABIN252657 : van Galen, Muris, Giroth, Vos, Ossenkoppele, Meijer, Oudejans: Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas. in Histopathology 2008 (PubMed)
    Show all 3 references for 252657

  3. Human Polyclonal TRAF2 Primary Antibody for ICC, FACS - ABIN252172 : Döppler, Liou, Storz: Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity. in PLoS ONE 2013 (PubMed)
    Show all 3 references for 252172

  4. Human Monoclonal TRAF2 Primary Antibody for IF, WB - ABIN659110 : Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. in Nature 2010 (PubMed)

  5. Human Polyclonal TRAF2 Primary Antibody for IF (p), IHC (p) - ABIN673479 : Lei, Bai, Yang, Lai, Qiu, Yang, Lian: Gsdma3 is a new factor needed for TNF-?-mediated apoptosis signal pathway in mouse skin keratinocytes. in Histochemistry and cell biology 2012 (PubMed)

  6. Human Polyclonal TRAF2 Primary Antibody for IHC, ELISA - ABIN190911 : Xu, Huang, Liu, Han: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against TRAF2 Interaction Partners

Human TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. TRAF2 and OTUD7B (show OTUD7B Antibodies) govern a ubiquitin-dependent switch that regulates mTORC2 (show CRTC2 Antibodies) signalling

  2. destabilization of TRAF2 by miR-17 reduced the ability of TRAF2 to associate with cIAP2 (show BIRC3 Antibodies), resulting in the downregulation of TNF-alpha (show TNF Antibodies)-induced NF-kappaBp65, c-Jun (show JUN Antibodies), and STAT3 (show STAT3 Antibodies) nuclear translocation and the production of IL-6 (show IL6 Antibodies), IL-8 (show IL8 Antibodies), MMP-1 (show MMP1 Antibodies), and MMP-13 (show MMP13 Antibodies) in human rheumatoid arthritis synovial fibroblasts.

  3. HOXA1 (show HOXA1 Antibodies)-mediated activation of NF-kappaB (show NFKB1 Antibodies) is non-transcriptional and the RBCK1 (show RBCK1 Antibodies) and TRAF2 influences on NF-kappaB (show NFKB1 Antibodies) are epistatic to HOXA1 (show HOXA1 Antibodies)

  4. RIPK1 (show RIPK1 Antibodies) collaborates with TRAF2 to inhibit murine and human hepatocarcinogenesis.

  5. Data suggest that TRAF2 (TNF receptor-associated factor 2) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (show TNFRSF1A Antibodies))-induced apoptosis, (2) TNFR2 (show TNFRSF1B Antibodies)- (tumor necrosis factor (show TNF Antibodies) receptor type 2)-induced non-canonical NFkappaB (show NFKB1 Antibodies) signaling, and (3) TNF- (tumor necrosis factor (show TNF Antibodies))-induced necroptosis. [REVIEW]

  6. Study presents the characterization of the peptide binding preferences of TRAFs 2, 3, and 5 using deep mutational scanning. The three TRAF (show TRAF1 Antibodies) proteins demonstrated different preferences for binding to members of the CD40 (show CD40 Antibodies) library, and three peptides from that library individually showed striking differences in affinity for the three TRAFs.

  7. The data demonstrate a novel and unexpected function of BIG1 (show CNTN3 Antibodies) that regulates TNFR1 (show TNFRSF1A Antibodies) signaling by targeting TRAF2.

  8. TRAF2 expression was increased in gastric cancer patients as a result of DNA hypomethylation.

  9. Data show that when death receptor 5 (DR5 (show TNFRSF10B Antibodies)) is suppressed, caspase-8 (show CASP8 Antibodies) may recruit and stabilize TNF receptor-associated factor 2 (TRAF2) to form a metastasis and invasion signaling complex, resulting in activation of ERK (show EPHB2 Antibodies) signaling.

  10. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14 (show DUSP14 Antibodies), leading to DUSP14 (show DUSP14 Antibodies) activation in T cells

Mouse (Murine) TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (show TRAF1 Antibodies)/NF-kappaB (show NFKB1 Antibodies)-regulated apoptosis and the p53 (show TP53 Antibodies)/PCNA (show PCNA Antibodies)- and ATM (show ATM Antibodies)/ATR (show ATR Antibodies)-Chk1 (show CHEK1 Antibodies)/2-controlled DNA-damage response pathways.

  2. Traf2 mediates the pro-survival pathway in the heart by suppressing necroptotic signaling.

  3. Targeting TRAF2 may be useful as a therapeutic approach for immunosuppression-free islet allograft survival that avoids the thromboembolic complications associated with the use of anti-CD40L (show CD40LG Antibodies) antibodies.

  4. Celastrol promotes Nur77 (show NR4A1 Antibodies) migration from the nucleus to mitochondria, where it is ubiquitinated by TRAF2. Ubiquitinated Nur77 (show NR4A1 Antibodies) then interacts with p62/SQSTM1 (show SQSTM1 Antibodies), leading to autophagy of dysfunctional mitochondria and alleviation of inflammation.

  5. TRAF2 and OTUD7B (show OTUD7B Antibodies) govern a ubiquitin-dependent switch that regulates mTORC2 (show CRTC2 Antibodies) signalling

  6. this study shows that TRAF2 and TRAF5 (show TRAF5 Antibodies) work as important regulators of the IL-6R signaling needed for Th17 development

  7. Keratinocyte-specific deletion of Traf2, but not Sphk1 (show SPHK1 Antibodies) deficiency, disrupted TNF (show TNF Antibodies) mediated NF-kappaB (show NFKB1 Antibodies) and MAP kinase (show MAPK1 Antibodies) signalling and caused epidermal hyperplasia and psoriatic skin inflammation.

  8. TRAF2 functions as a key activator of MST1 (show MST1 Antibodies) in oxidative stress-induced (show SQSTM1 Antibodies) intracellular signaling processes.

  9. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

  10. NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1 (show TRAF1 Antibodies)), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2 (show BIRC3 Antibodies)), and Ferritin heavy chain (FTH1 (show FTH1 Antibodies)) were increased following Losartan treatment

TRAF2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.

Alternative names and synonyms associated with TRAF2

  • TNF-receptor-associated factor 2 (Traf2) antibody
  • conjugal transfer protein TraF (traF2) antibody
  • TNF receptor-associated factor 2 (TRAF2) antibody
  • TNF receptor-associated factor 2 (Traf2) antibody
  • Tnf receptor-associated factor 2 (Traf2) antibody
  • AI325259 antibody
  • MGC:45012 antibody
  • TANK antibody
  • TRAP antibody
  • TRAP3 antibody

Protein level used designations for TRAF2

GLEAN_07706 , conjugal transfer protein TraF , E3 ubiquitin-protein ligase TRAF2 , tumor necrosis factor type 2 receptor associated protein 3 , tumor necrosis factor type 2 receptor-associated protein 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2

661716 Tribolium castaneum
5816473 Bordetella petrii DSM 12804
10845633 Oligotropha carboxidovorans OM5
7186 Homo sapiens
480673 Canis lupus familiaris
512355 Bos taurus
22030 Mus musculus
311786 Rattus norvegicus
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