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Browse our anti-TRAF2 (TRAF2) Antibodies

Full name:
anti-TNF Receptor-Associated Factor 2 Antibodies (TRAF2)
On are 189 TNF Receptor-Associated Factor 2 (TRAF2) Antibodies from 26 different suppliers available. Additionally we are shipping TRAF2 Proteins (9) and many more products for this protein. A total of 223 TRAF2 products are currently listed.
AI325259, MGC:45012, TANK, TRAP, TRAP3
list all antibodies Gene Name GeneID UniProt
TRAF2 7186 Q12933
TRAF2 22030 P39429
TRAF2 311786  

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anti-Human TRAF2 Antibodies:

anti-Mouse (Murine) TRAF2 Antibodies:

anti-Rat (Rattus) TRAF2 Antibodies:

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Top referenced anti-TRAF2 Antibodies

  1. Human Monoclonal TRAF2 Primary Antibody for WB - ABIN967631 : Arch, Gedrich, Thompson: Translocation of TRAF proteins regulates apoptotic threshold of cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 7 references for ABIN967631

  2. Human Monoclonal TRAF2 Primary Antibody for IHC (p), IHC - ABIN252657 : van Galen, Muris, Giroth, Vos, Ossenkoppele, Meijer, Oudejans: Expression of TNF-receptor associated factor 2 correlates with poor progression-free survival time in ABC-like primary nodal diffuse large B-cell lymphomas. in Histopathology 2008 (PubMed)
    Show all 3 references for ABIN252657

  3. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (p) - ABIN501020 : van Kooten, Banchereau: CD40-CD40 ligand. in Journal of leukocyte biology 2000 (PubMed)
    Show all 3 references for ABIN501020

  4. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (p) - ABIN501022 : Grech, Amesbury, Chan, Gardam, Basten, Brink: TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells. in Immunity 2004 (PubMed)
    Show all 3 references for ABIN501022

  5. Human Polyclonal TRAF2 Primary Antibody for EIA, WB - ABIN4620489 : Merluzzi, DOrlando, Leonardi, Vitale, Pucillo: TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation. in Molecular immunology 2007 (PubMed)
    Show all 3 references for ABIN4620489

  6. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (fro) - ABIN401469 : Li, Wang, Berman, Zhang, Dorf: RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. in Molecular cell 2006 (PubMed)

  7. Dog (Canine) Polyclonal TRAF2 Primary Antibody for WB - ABIN374824 : Xu, Huang, Liu, Han: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. in The Journal of biological chemistry 2006 (PubMed)

  8. Human Monoclonal TRAF2 Primary Antibody for IF, WB - ABIN659110 : Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. in Nature 2010 (PubMed)

More Antibodies against TRAF2 Interaction Partners

Human TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. HOXA1 (show HOXA1 Antibodies)-mediated activation of NF-kappaB (show NFKB1 Antibodies) is non-transcriptional and the RBCK1 (show RBCK1 Antibodies) and TRAF2 influences on NF-kappaB (show NFKB1 Antibodies) are epistatic to HOXA1 (show HOXA1 Antibodies)

  2. RIPK1 (show RIPK1 Antibodies) collaborates with TRAF2 to inhibit murine and human hepatocarcinogenesis.

  3. Data suggest that TRAF2 (TNF receptor-associated factor 2) negatively regulates (1) TNFR1- (tumor necrosis factor binding protein 1 (show TNFRSF1A Antibodies))-induced apoptosis, (2) TNFR2 (show TNFRSF1B Antibodies)- (tumor necrosis factor (show TNF Antibodies) receptor type 2)-induced non-canonical NFkappaB (show NFKB1 Antibodies) signaling, and (3) TNF- (tumor necrosis factor (show TNF Antibodies))-induced necroptosis. [REVIEW]

  4. Study presents the characterization of the peptide binding preferences of TRAFs 2, 3, and 5 using deep mutational scanning. The three TRAF (show TRAF1 Antibodies) proteins demonstrated different preferences for binding to members of the CD40 (show CD40 Antibodies) library, and three peptides from that library individually showed striking differences in affinity for the three TRAFs.

  5. The data demonstrate a novel and unexpected function of BIG1 (show CNTN3 Antibodies) that regulates TNFR1 (show TNFRSF1A Antibodies) signaling by targeting TRAF2.

  6. TRAF2 expression was increased in gastric cancer patients as a result of DNA hypomethylation.

  7. Data show that when death receptor 5 (DR5 (show TNFRSF10B Antibodies)) is suppressed, caspase-8 (show CASP8 Antibodies) may recruit and stabilize TNF receptor-associated factor 2 (TRAF2) to form a metastasis and invasion signaling complex, resulting in activation of ERK (show EPHB2 Antibodies) signaling.

  8. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14 (show DUSP14 Antibodies), leading to DUSP14 (show DUSP14 Antibodies) activation in T cells

  9. There was a significant positive correlation between TRAF2 and TRAF4 (show TRAF4 Antibodies) expression levels in malignant pleural effusion cells

  10. Data show that ectopic expression of interferon regulatory factor 1 (IRF-1 (show IRF1 Antibodies)) reduces NF-kappa B (show NFKB1 Antibodies) activity and suppresses TNF receptor-associated factor 2 (TRAF2) and inhibitor of apoptosis 1 (show BIRC2 Antibodies) protein (cIAP1 (show BIRC2 Antibodies)) expression in breast cancer cells.

Mouse (Murine) TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. Keratinocyte-specific deletion of Traf2, but not Sphk1 (show SPHK1 Antibodies) deficiency, disrupted TNF (show TNF Antibodies) mediated NF-kappaB (show NFKB1 Antibodies) and MAP kinase (show MAPK1 Antibodies) signalling and caused epidermal hyperplasia and psoriatic skin inflammation.

  2. TRAF2 functions as a key activator of MST1 (show MST1 Antibodies) in oxidative stress-induced (show SQSTM1 Antibodies) intracellular signaling processes.

  3. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

  4. NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1 (show TRAF1 Antibodies)), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2 (show BIRC3 Antibodies)), and Ferritin heavy chain (FTH1 (show FTH1 Antibodies)) were increased following Losartan treatment

  5. These studies demonstrate a critical role for TRAF2 in the maintenance of peripheral CD8 (show CD8A Antibodies)(+) CD44 (show CD44 Antibodies)(hi) CD122 (show IL2RB Antibodies)(+) T-cell and NKT (show CTSL1 Antibodies)-cell homeostasis by modulating sensitivity to T-cell intrinsic growth factors such as IL-15 (show IL15 Antibodies).

  6. HGK/MAP4K4 (show MAP4K4 Antibodies) deficiency has a role in inducing TRAF2 stabilization and Th17 differentiation leading to insulin (show INS Antibodies) resistance

  7. identifying the CYLD (show CYLD Antibodies)-TRAF2-p38MAPK (show MAPK14 Antibodies) pathway as a novel important regulator of HSC (show FUT1 Antibodies) function restricting HSC (show FUT1 Antibodies) cycling and promoting dormancy.

  8. Data indicate that caspase-8 (show CASP8 Antibodies) activity is lost upon deletion of c-FLIPL (show CFLAR Antibodies), and p43FLIP rescues caspase-8 (show CASP8 Antibodies) activity through Raf1 (show RAF1 Antibodies), TRAF2, and RIPK1 (show RIPK1 Antibodies) association, augmenting ERK (show EPHB2 Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways

  9. IpaH0722 dampens the acute inflammatory response by preferentially inhibiting the PKC-mediated activation of NF-kappaB by ubiquitinating TRAF2, a molecule downstream of PKC, and by promoting its proteasome-dependent degradation.

  10. Data indicate that deletion of Tnfr1 (show TNFRSF1A Antibodies) gene more efficiently decreased the percentages of IL-10 (show IL10 Antibodies)-secreting neutrophils in PB and BM cells from tumor necrosis factor (TNF (show TNF Antibodies)) receptor-associated factor (Traf)2(-/-) mice.

TRAF2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.

Alternative names and synonyms associated with TRAF2

  • TNF-receptor-associated factor 2 (Traf2) antibody
  • conjugal transfer protein TraF (traF2) antibody
  • TNF receptor-associated factor 2 (TRAF2) antibody
  • TNF receptor-associated factor 2 (Traf2) antibody
  • Tnf receptor-associated factor 2 (Traf2) antibody
  • AI325259 antibody
  • MGC:45012 antibody
  • TANK antibody
  • TRAP antibody
  • TRAP3 antibody

Protein level used designations for TRAF2

GLEAN_07706 , conjugal transfer protein TraF , E3 ubiquitin-protein ligase TRAF2 , tumor necrosis factor type 2 receptor associated protein 3 , tumor necrosis factor type 2 receptor-associated protein 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2

661716 Tribolium castaneum
5816473 Bordetella petrii DSM 12804
10845633 Oligotropha carboxidovorans OM5
7186 Homo sapiens
480673 Canis lupus familiaris
512355 Bos taurus
22030 Mus musculus
311786 Rattus norvegicus
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