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Browse our anti-TRAF2 (TRAF2) Antibodies

Full name:
anti-TNF Receptor-Associated Factor 2 Antibodies (TRAF2)
On are 160 TNF Receptor-Associated Factor 2 (TRAF2) Antibodies from 24 different suppliers available. Additionally we are shipping TRAF2 Proteins (8) and many more products for this protein. A total of 194 TRAF2 products are currently listed.
AI325259, MGC:45012, TANK, TRAP, TRAP3
list all antibodies Gene Name GeneID UniProt
TRAF2 7186 Q12933
TRAF2 22030 P39429
TRAF2 311786  

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anti-Human TRAF2 Antibodies:

anti-Mouse (Murine) TRAF2 Antibodies:

anti-Rat (Rattus) TRAF2 Antibodies:

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Top referenced anti-TRAF2 Antibodies

  1. Human Monoclonal TRAF2 Primary Antibody for WB - ABIN967631 : Arch, Gedrich, Thompson: Translocation of TRAF proteins regulates apoptotic threshold of cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 7 references for ABIN967631

  2. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (p) - ABIN501022 : van Kooten, Banchereau: CD40-CD40 ligand. in Journal of leukocyte biology 2000 (PubMed)
    Show all 3 references for ABIN501022

  3. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (p) - ABIN501020 : Grech, Amesbury, Chan, Gardam, Basten, Brink: TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells. in Immunity 2004 (PubMed)
    Show all 3 references for ABIN501020

  4. Human Polyclonal TRAF2 Primary Antibody for EIA, WB - ABIN360166 : Merluzzi, DOrlando, Leonardi, Vitale, Pucillo: TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation. in Molecular immunology 2007 (PubMed)
    Show all 3 references for ABIN360166

  5. Dog (Canine) Polyclonal TRAF2 Primary Antibody for WB - ABIN374824 : Xu, Huang, Liu, Han: Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. in The Journal of biological chemistry 2006 (PubMed)

  6. Human Monoclonal TRAF2 Primary Antibody for IF, WB - ABIN659110 : Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. in Nature 2010 (PubMed)

  7. Human Polyclonal TRAF2 Primary Antibody for EIA, IHC (fro) - ABIN401470 : Li, Wang, Berman, Zhang, Dorf: RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling. in Molecular cell 2006 (PubMed)

More Antibodies against TRAF2 Interaction Partners

Human TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14 (show DUSP14 Antibodies), leading to DUSP14 (show DUSP14 Antibodies) activation in T cells

  2. There was a significant positive correlation between TRAF2 and TRAF4 (show TRAF4 Antibodies) expression levels in malignant pleural effusion cells

  3. Data show that ectopic expression of interferon regulatory factor 1 (IRF-1 (show IRF1 Antibodies)) reduces NF-kappa B (show NFKB1 Antibodies) activity and suppresses TNF receptor-associated factor 2 (TRAF2) and inhibitor of apoptosis 1 (show BIRC2 Antibodies) protein (cIAP1 (show BIRC2 Antibodies)) expression in breast cancer cells.

  4. The results identify TRAF2 as an important biological suppressor of necroptosis in vitro and in vivo.

  5. MAVS50, exposing a degenerate TRAF (show TRAF1 Antibodies)-binding motif within its N-terminus, effectively competed with full-length MAVS (show MAVS Antibodies) for recruiting TRAF2 and TRAF6 (show TRAF6 Antibodies)

  6. Presented is the trimer-to-monomer equilibrium transition of the TRAF2 C-terminal domain using both chemical (dilution/guanidinium hydrochloride) and mechanical stress (high pressure) to induce the dissociation of the native protein into subunits.

  7. Knockdown of IRE1alpha (show ERN1 Antibodies) by siRNA dramatically abrogated CXC195-induced activation of TRAF2, ASK and JNK (show MAPK8 Antibodies), formation of an IRE1alpha (show ERN1 Antibodies)-TRAF2-ASK1 (show MAP3K5 Antibodies) complex and caspase (show CASP3 Antibodies)- and mitochondrial-dependent apoptosis in T24 cells

  8. PP4R1 (show PPP4R1 Antibodies) could mediate the dephosphorylation of TRAF2 Ser11.

  9. TRAF2 acts as an antagonist of TRAIL- and CD95L (show FASL Antibodies)-induced necroptosis.

  10. Data indicate that TRAF interacting protein (show TANK Antibodies) TRIP negatively regulates the TNFR (show TNFRSF1A Antibodies)-associated factor 2 (TRAF2) ubiquitin-dependent pathway by modulating the TRAF2-sphingosine 1-phosphate (S1P (show MBTPS1 Antibodies)) interaction.

Mouse (Murine) TNF Receptor-Associated Factor 2 (TRAF2) interaction partners

  1. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.

  2. NFkappaB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1 (show TRAF1 Antibodies)), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2 (show BIRC3 Antibodies)), and Ferritin heavy chain (FTH1 (show FTH1 Antibodies)) were increased following Losartan treatment

  3. These studies demonstrate a critical role for TRAF2 in the maintenance of peripheral CD8 (show CD8A Antibodies)(+) CD44 (show CD44 Antibodies)(hi) CD122 (show IL2RB Antibodies)(+) T-cell and NKT (show CTSL1 Antibodies)-cell homeostasis by modulating sensitivity to T-cell intrinsic growth factors such as IL-15 (show IL15 Antibodies).

  4. HGK/MAP4K4 (show MAP4K4 Antibodies) deficiency has a role in inducing TRAF2 stabilization and Th17 differentiation leading to insulin (show INS Antibodies) resistance

  5. identifying the CYLD (show CYLD Antibodies)-TRAF2-p38MAPK (show MAPK14 Antibodies) pathway as a novel important regulator of HSC (show FUT1 Antibodies) function restricting HSC (show FUT1 Antibodies) cycling and promoting dormancy.

  6. Data indicate that caspase-8 (show CASP8 Antibodies) activity is lost upon deletion of c-FLIPL (show CFLAR Antibodies), and p43FLIP rescues caspase-8 (show CASP8 Antibodies) activity through Raf1 (show RAF1 Antibodies), TRAF2, and RIPK1 (show RIPK1 Antibodies) association, augmenting ERK (show EPHB2 Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways

  7. IpaH0722 dampens the acute inflammatory response by preferentially inhibiting the PKC-mediated activation of NF-kappaB by ubiquitinating TRAF2, a molecule downstream of PKC, and by promoting its proteasome-dependent degradation.

  8. Data indicate that deletion of Tnfr1 (show TNFRSF1A Antibodies) gene more efficiently decreased the percentages of IL-10 (show IL10 Antibodies)-secreting neutrophils in PB and BM cells from tumor necrosis factor (TNF (show TNF Antibodies)) receptor-associated factor (Traf)2(-/-) mice.

  9. Expression of endogenous TRAF2 is negligible in Traf2DN-transgenic B cells compared with wild-type mice.

  10. hepatic TRAF2 cell autonomously promotes hepatic gluconeogenesis by enhancing the hyperglycemic response to glucagon (show GCG Antibodies).

TRAF2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.

Alternative names and synonyms associated with TRAF2

  • TNF-receptor-associated factor 2 (Traf2) antibody
  • conjugal transfer protein TraF (traF2) antibody
  • TNF receptor-associated factor 2 (TRAF2) antibody
  • TNF receptor-associated factor 2 (Traf2) antibody
  • Tnf receptor-associated factor 2 (Traf2) antibody
  • AI325259 antibody
  • MGC:45012 antibody
  • TANK antibody
  • TRAP antibody
  • TRAP3 antibody

Protein level used designations for TRAF2

GLEAN_07706 , conjugal transfer protein TraF , E3 ubiquitin-protein ligase TRAF2 , tumor necrosis factor type 2 receptor associated protein 3 , tumor necrosis factor type 2 receptor-associated protein 3 , TRAF family member-associated NFKB activator , TNF receptor-associated factor 2

661716 Tribolium castaneum
5816473 Bordetella petrii DSM 12804
10845633 Oligotropha carboxidovorans OM5
7186 Homo sapiens
480673 Canis lupus familiaris
512355 Bos taurus
22030 Mus musculus
311786 Rattus norvegicus
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