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|Application / Reactivity||Human|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunofluorescence (IF)||6 Antibodies|
|Immunofluorescence (fixed cells) (IF/ICC)||1 Antibodies|
|Immunohistochemistry (IHC)||16 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||10 Antibodies|
|Immunoprecipitation (IP)||7 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Western Blotting (WB)||57 Antibodies|
|Antigen||TNF Receptor-Associated Factor 5 (TRAF5) Antibodies|
|Epitope||AA 62-75, N-Term Alternatives|
|Conjugate||This TRAF5 antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-TRAF5 AntibodyTarget Details TRAF5 Application Details Handling Images
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for TNF receptor-associated factor 5(TRAF5) detection. Tested with WB in Human.
Gene Name: TNF receptor-associated factor 5
Protein Name: TNF receptor-associated factor 5
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human TRAF5(62-75aa HRFCQHCILSLREL), different from the related mouse sequence by two amino acids.|
Target Details TRAF5Product Details anti-TRAF5 Antibody Application Details Handling Images back to top
|Alternative Name||TRAF5 (TRAF5 Antibody Abstract)|
|Background||TNF receptor-associated factor 5, also known as RNF84, is a protein that in humans is encoded by the TRAF5 gene. The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor(TRAF) protein family. Fluorescence in situ hybridization confirmed the regional localization of human TRAF5 to chromosome 1q32.2-q32.3. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor(TNF) receptor cytoplasmic domains and mediates TNF-induced activation. It is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. It seems to be involved in apoptosis.|
|Research Area||Immunology, Innate Immunity, Cytokines|
|Pathways||NF-kappaB Signaling, Apoptosis|
Application DetailsProduct Details anti-TRAF5 Antibody Target Details TRAF5 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TRAF5 Antibody Target Details TRAF5 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Thimerosal (Merthiolate),Sodium azide a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
|Expiry Date||12 months|
ImagesProduct Details anti-TRAF5 Antibody Target Details TRAF5 Application Details Handling back to top