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Browse our anti-TRAF6 (TRAF6) Antibodies

Full name:
anti-TNF Receptor-Associated Factor 6 Antibodies (TRAF6)
On are 151 TNF Receptor-Associated Factor 6 (TRAF6) Antibodies from 30 different suppliers available. Additionally we are shipping TRAF6 Kits (15) and TRAF6 Proteins (14) and many more products for this protein. A total of 200 TRAF6 products are currently listed.
2310003F17Rik, AI851288, C630032O20Rik, CG10961, Dmel\\CG10961, dtraf2, dTRAF6, fi15f02, GB10539, MGC:3310, RNF85, TRAF, Traf2, TRAF6, wu:fi15f02, xtraf6, zgc:63704
list all antibodies Gene Name GeneID UniProt
TRAF6 22034 P70196
TRAF6 7189 Q9Y4K3
TRAF6 311245 B5DF45

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anti-Mouse (Murine) TRAF6 Antibodies:

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anti-Rat (Rattus) TRAF6 Antibodies:

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Top referenced anti-TRAF6 Antibodies

  1. Human Polyclonal TRAF6 Primary Antibody for WB - ABIN1881900 : Hinz, Stilmann, Arslan, Khanna, Dittmar, Scheidereit: A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. in Molecular cell 2010 (PubMed)
    Show all 4 references for ABIN1881900

  2. Cow (Bovine) Polyclonal TRAF6 Primary Antibody for WB - ABIN2779305 : Jazdzewski, Murray, Franssila, Jarzab, Schoenberg, de la Chapelle: Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  3. Human Polyclonal TRAF6 Primary Antibody for EIA, IF - ABIN501028 : Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003 (PubMed)

More Antibodies against TRAF6 Interaction Partners

Fruit Fly (Drosophila melanogaster) TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. we found that reactive oxygen species-induced autophagy acts as a negative feedback regulator of JNK (show MAPK8 Antibodies) activity by dissociating Atg9 (show ATG9A Antibodies)/mAtg9 (show ATG9A Antibodies) from dTRAF2/TRAF6 in Drosophila.

  2. null mutant of DTRAF2 showed immune deficiencies in which NF-kappaB nuclear translocation and antimicrobial gene transcription against microbial infection were severely impaired

Mouse (Murine) TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. this study shows that the absence TRAF6 expression by dendritic cells leads to spontaneous generation of Th2-associated immune responses and increased susceptibility to model antigen-induced asthma

  2. MiR (show MLXIP Antibodies)-144 reduces the antiviral response by attenuating the TRAF6-IRF7 (show IRF7 Antibodies) pathway to alter the cellular antiviral transcriptional landscape.

  3. Data indicate a role of microRNA miR (show MLXIP Antibodies)-146a in the modulation of host defense against mycobacterial infection by repressing nitric oxide (NO) production via targeting tumor necrosis factor (TNF (show TNF Antibodies)) receptor-associated factor 6 (TRAF6), which may provide a promising therapeutic target for tuberculosis.

  4. CD137 (show TNFRSF9 Antibodies) Regulates NFATc1 (show NFATC1 Antibodies) Expression in Mouse VSMCs through TRAF6/NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) Signaling Pathway.

  5. TRAF6 was required for the activation of MAPKs ERK1/2 (show MAPK1/3 Antibodies) and JNK1 (show MAPK8 Antibodies)/2

  6. Results suggest that microRNA-146a-5p attenuates neuropathic pain partly through inhibition of tumor necrosis factor (show TNF Antibodies) receptor associated factor-6 and its downstream c-jun N-terminal kinase/CCL2 (show CCL2 Antibodies) signaling.

  7. we demonstrate that CpG treatment leads to ubiquitin-mediated degradation of DOK3 (show DOK3 Antibodies) via interaction with an E3 ligase TNFR (show TNFRSF1A Antibodies)-associated factor 6 (TRAF6).

  8. TRAF6 is determined to be a direct E3 ligase for GSK3beta (show GSK3b Antibodies), and TRAF6-mediated GSK3beta (show GSK3b Antibodies) ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 (show TLR3 Antibodies) adaptor protein TRIF (show RNF138 Antibodies)-assembled signalling complex.

  9. TIFAB (show TIFAB Antibodies) loss increases TRAF6 protein and the dynamic range of TLR4 (show TLR4 Antibodies) signaling

  10. The MYSM1 (show MYSM1 Antibodies) SWIRM domain interacts with TRAF6 to terminate PRR (show PVRL1 Antibodies) pathways for pro-inflammatory and type I interferon (show IFNA Antibodies) responses.

Zebrafish TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. we have now analyzed the in vivo function of Traf6 in the innate immune response without interference of adaptive immunity

  2. Full-length traf6 was functionally characterized.

Human TNF Receptor-Associated Factor 6 (TRAF6) interaction partners

  1. TRAF6 expression was decreased in tympanic membrane of otitis media patients.

  2. Peripheral blood levels of S100A8 (show S100A8 Antibodies) and TRAF6 in SAE patients were elevated and might be related to the severity of SAE and predict the outcome of SAE.

  3. Low TRAF6 expression is associated with Graves' disease.

  4. MiR (show MLXIP Antibodies)-146a regulates inflammatory macrophage infiltration in Polymyositis/Dermatomyositis by targeting TRAF6 and affecting the IL-17 (show IL17A Antibodies)/ICAM-1 (show ICAM1 Antibodies) pathway.

  5. Study demonstrates that TRAF6 is upregulated in human lung cancer cells, and siRNA-induced TRAF6 knockdown inhibits the invasion of lung cancer cells and promotes apoptosis.

  6. High TRAF6 expression is associated with melanoma invasion and metastasis.

  7. The expression of TRAF6 was positively correlated with an advanced N stage and acted as a predictor of a poor prognosis in patients with gastric cancer

  8. DK1 (show DOLK Antibodies) inhibits the formation of the TAK1 (show MAP3K7 Antibodies)-TAB2 (show TAB2 Antibodies)-TRAF6 complex and leads to the inhibition of TRAF6 ubiquitination.

  9. DAT (show SLC6A3 Antibodies) stabilized IkBa (show NFKBIA Antibodies) by inhibiting the phosphorylation of Ika by the IkB (show NFKBIB Antibodies) kinase (IKK (show CHUK Antibodies)) complex. DAT (show SLC6A3 Antibodies) induced proteasomal degradation of TRAF6, and DAT (show SLC6A3 Antibodies) suppressed IKKb (show IKBKB Antibodies)-phosphorylation through downregulation of TRAF6

  10. TRAF6 may be involved in cell migration, invasion, and apoptosis of SPC (show UCN3 Antibodies)-A-1 cells, possibly through regulating the NF-B-CD24 (show CD24 Antibodies)/CXCR4 (show CXCR4 Antibodies) pathway..

TRAF6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names and synonyms associated with TRAF6

  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6-b) antibody
  • TNF-receptor-associated factor 6 (Traf6) antibody
  • TNF receptor-associated factor 6 (TRAF6) antibody
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (traf6) antibody
  • TNF receptor-associated factor 6 (traf6) antibody
  • TNF receptor-associated factor 6 (Traf6) antibody
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) antibody
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase (Traf6) antibody
  • 2310003F17Rik antibody
  • AI851288 antibody
  • C630032O20Rik antibody
  • CG10961 antibody
  • Dmel\\CG10961 antibody
  • dtraf2 antibody
  • dTRAF6 antibody
  • fi15f02 antibody
  • GB10539 antibody
  • MGC:3310 antibody
  • RNF85 antibody
  • TRAF antibody
  • Traf2 antibody
  • TRAF6 antibody
  • wu:fi15f02 antibody
  • xtraf6 antibody
  • zgc:63704 antibody

Protein level used designations for TRAF6

TNF receptor-associated factor 6-B , E3 ubiquitin-protein ligase TRAF6 , CG10961-PA , TNF-receptor-associated factor 2 , Traf6-PA , TNF receptor-associated factor 6 , TNF receptor-associated factor 6-like , RING finger protein 85 , interleukin-1 signal transducer , TNF-receptor associated factor 6

444777 Xenopus laevis
31746 Drosophila melanogaster
423163 Gallus gallus
451702 Pan troglodytes
493524 Xenopus (Silurana) tropicalis
551819 Apis mellifera
100010055 Monodelphis domestica
100174890 Gasterosteus aculeatus
100395364 Callithrix jacchus
100449432 Pongo abelii
100510771 Anolis carolinensis
100544809 Meleagris gallopavo
100595327 Nomascus leucogenys
22034 Mus musculus
539124 Bos taurus
554561 Danio rerio
7189 Homo sapiens
311245 Rattus norvegicus
100688110 Canis lupus familiaris
396629 Sus scrofa
716907 Macaca mulatta
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