anti-Mouse (Murine) TRAF6 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended TRAF6 Antibody (supplied by: Log in to see )

Antigen
TNF Receptor-Associated Factor 6 (TRAF6) Antibodies
  • rnf85
  • traf6
  • xtraf6
  • CG10961
  • DTRAF2
  • Dmel\\CG10961
  • TRAF
  • TRAF2
  • TRAF6
  • Traf2
  • dTRAF2
  • dTRAF6
  • dTraf2
  • dtraf2
  • GB10539
  • 2310003F17Rik
  • AI851288
  • C630032O20Rik
  • fi15f02
  • wu:fi15f02
  • zgc:63704
  • MGC:3310
  • RNF85
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase
  • TNF-receptor-associated factor 6
  • TNF receptor-associated factor 6
  • traf6-b
  • Traf6
  • TRAF6
  • traf6
Reactivity
Human, Mouse (Murine), Rat (Rattus)
156
83
71
10
8
6
5
3
3
1
1
Host
Rabbit
137
28
2
Clonality
Polyclonal
Conjugate
This TRAF6 antibody is conjugated to Alexa Fluor 647
5
5
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
135
48
37
32
27
23
23
20
12
5
5
3
2
2
1
1
Options
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Catalog No. ABIN918441
$ 405.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN738906 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2807157 IF (p) Alexa Fluor 594 Rabbit IgG AA 500-530 Log in to see Polyclonal
1 ABIN738911 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN738910 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN738909 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN738912 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN738913 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN918440 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN918438 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN918439 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN5011858 IF (p) Alexa Fluor 750 Rabbit IgG AA 500-530 Log in to see Polyclonal
1 ABIN5011857 IF (p) Alexa Fluor 680 Rabbit IgG AA 500-530 Log in to see Polyclonal

General

Antigen TNF Receptor-Associated Factor 6 (TRAF6) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(156), (83), (71), (10), (8), (6), (5), (3), (3), (1), (1)
Host Rabbit
(137), (28), (2)
Clonality
Polyclonal
Conjugate This TRAF6 antibody is conjugated to Alexa Fluor 647
(5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(135), (48), (37), (32), (27), (23), (23), (20), (12), (5), (5), (3), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-TRAF6 Antibody

Target Details TRAF6 Application Details Handling References for anti-TRAF6 antibody (ABIN918441) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse TRAF6
Isotype IgG

Target Details TRAF6

Product Details anti-TRAF6 Antibody Application Details Handling References for anti-TRAF6 antibody (ABIN918441) Images back to top
Antigen
Alternative Name Traf6 (TRAF6 Antibody Abstract)
Background

E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation (By similarity). Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.

Subcellular location: Cytoplasm, Nucleus

Synonyms: AI851288, 2310003F17Rik, C630032O20Rik, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, Traf6

Gene ID 22034
UniProt P70196
Research Area Immunology, Innate Immunity, Atherosclerosis, Apoptosis/Necrosis
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-TRAF6 Antibody Target Details TRAF6 Handling References for anti-TRAF6 antibody (ABIN918441) Images back to top
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-TRAF6 Antibody Target Details TRAF6 Application Details References for anti-TRAF6 antibody (ABIN918441) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months

References for anti-TRAF6 antibody (ABIN918441)

Product Details anti-TRAF6 Antibody Target Details TRAF6 Application Details Handling Images back to top
Product cited in:

Qi, Pradipta, Li, Zhao, Lu, Fu, Wei, Hsung, Tanaka, Zhou: "Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 35, 2017 Method employed by authors: Immunofluorescence (fixed cells) (IF/ICC) (Sample species: Human).