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anti-Dog (Canine) Tumor Necrosis Factor antibody for Functional Studies

Recommended Tumor Necrosis Factor Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor (TNF) Antibodies
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Reactivity
Cow (Bovine), Dog (Canine), Human, Monkey
1215
443
357
141
135
119
119
56
51
40
28
17
11
9
9
7
6
4
4
4
4
2
1
1
1
Host
Mouse
923
482
182
42
10
9
7
6
3
2
Clonality
Monoclonal
Conjugate
This Tumor Necrosis Factor antibody is un-conjugated
160
95
70
49
32
30
27
26
25
25
25
25
25
25
24
24
24
19
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA)
865
839
592
307
273
229
201
180
137
119
96
62
27
26
25
22
20
16
14
8
7
6
6
6
5
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN1109393
$ 423.50
Plus shipping costs $45.00

Top referenced anti-Tumor Necrosis Factor antibody for Functional Studies

Similar anti-Tumor Necrosis Factor Antibodies

Application / Reactivity Human Dog (Canine) Cow (Bovine) Monkey
Immunofluorescence (fixed cells) (IF/ICC) 7 Antibodies 2 Antibodies 1 Antibodies 6 Antibodies
Activity Inhibition (Act Inh) 2 Antibodies
Cytometry by Time of Flight (CyTOF) 27 Antibodies 10 Antibodies
Immunohistochemistry (Free Floating) (IHC (ff)) 2 Antibodies
Western Blotting (WB) 529 Antibodies 35 Antibodies 26 Antibodies 64 Antibodies
Transfected Cell Culture (TCC) 1 Antibodies
Radioimmunoassay (RIA) 17 Antibodies 2 Antibodies
Protein Assay (PrA) 2 Antibodies
Neutralization (Neut) 63 Antibodies 3 Antibodies 2 Antibodies 1 Antibodies

General

Antigen Tumor Necrosis Factor (TNF) Antibodies
Reactivity Cow (Bovine), Dog (Canine), Human, Monkey
(1215), (443), (357), (141), (135), (119), (119), (56), (51), (40), (28), (17), (11), (9), (9), (7), (6), (4), (4), (4), (4), (2), (1), (1), (1)
Host Mouse
(923), (482), (182), (42), (10), (9), (7), (6), (3), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Tumor Necrosis Factor antibody is un-conjugated
(160), (95), (70), (49), (32), (30), (27), (26), (25), (25), (25), (25), (25), (25), (24), (24), (24), (19), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA)
(865), (839), (592), (307), (273), (229), (201), (180), (137), (119), (96), (62), (27), (26), (25), (22), (20), (16), (14), (8), (7), (6), (6), (6), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Tumor Necrosis Factor Antibody

Target Details Tumor Necrosis Factor Application Details Handling References for anti-Tumor Necrosis Factor Antibody (ABIN1109393) Images
Cross-Reactivity (Details) Species reactivity (tested):Human, Bovine, Canine, Monkey
Purification Protein G
Clone 5N
Isotype IgG2a

Target Details Tumor Necrosis Factor

Product Details anti-Tumor Necrosis Factor Antibody Application Details Handling References for anti-Tumor Necrosis Factor Antibody (ABIN1109393) Images back to top
Antigen
Alternative Name Tumor Necrosis Factor (TNF-Alpha) (TNF Antibody Abstract)
Background Tumor necrosis factor-alpha (TNF-alpha), a homotrimeric 17 KD protein, is a potent mediator of inflammatory and metabolic functions. TNF-alpha was originally detected as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Further TNF-alpha has been implied as central mediator in shock induced by gram negative micro-organisms. The cytokine TNF-alpha is found to be a central mediator in many inflammatory and immunological processes: it can be induced by various products of micro-organisms and by various cytokines but it also induces on its turn the production of many cytokines. Signal transduction occurs via two types of TNF-receptors, the TNF-receptors I and II. The receptors differ strongly in their intra-cellular signaling pathways. The TNF-alpha trimer interacts with either of the two types of TNF-R leading to receptor cross-linking.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
Gene ID 9606
UniProt P01375
Research Area Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Cancer, Virology
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Application Details

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Handling References for anti-Tumor Necrosis Factor Antibody (ABIN1109393) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Application Details References for anti-Tumor Necrosis Factor Antibody (ABIN1109393) Images back to top
Buffer PBS, 0.1 % bovine serum albumin
Storage 4 °C
Storage Comment Store at 2 - 8 °C.

References for anti-Tumor Necrosis Factor Antibody (ABIN1109393)

Product Details anti-Tumor Necrosis Factor Antibody Target Details Tumor Necrosis Factor Application Details Handling Images back to top
Background publications

Song, Fox, Gallo, Rosenberg, Jordan, Shealy, Wagner: "Effects of 2 different anti-tumor necrosis factor-alpha agents in a primate model of subcutaneous abscess formation." in: The Journal of infectious diseases, Vol. 185, Issue 2, pp. 204-13, 2002

Petyovka, Lyach, Voitenok: "Homologous ELISA for detection of oligomeric human TNF: properties of the assay." in: Journal of immunological methods, Vol. 186, Issue 2, pp. 161-70, 1995