Browse our anti-ADAM10 (ADAM10) Antibodies

Full name:
anti-ADAM Metallopeptidase Domain 10 Antibodies (ADAM10)
On www.antibodies-online.com are 149 ADAM Metallopeptidase Domain 10 (ADAM10) Antibodies from 31 different suppliers available. Additionally we are shipping ADAM10 Kits (43) and ADAM10 Proteins (21) and many more products for this protein. A total of 217 ADAM10 products are currently listed.
Synonyms:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
list all antibodies Gene Name GeneID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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anti-Mouse (Murine) ADAM10 Antibodies:

anti-Human ADAM10 Antibodies:

anti-Rat (Rattus) ADAM10 Antibodies:

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Top referenced anti-ADAM10 Antibodies

  1. Human Polyclonal ADAM10 Primary Antibody for WB - ABIN264988 : Rosendahl, Ko, Long, Brewer, Rosenzweig, Hedl, Anderson, Pyle, Moreland, Meyers, Kohno, Lyons, Lichenstein: Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for 264988

  2. Cow (Bovine) Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN401037 : Pan, Rubin: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. in Cell 1997 (PubMed)
    Show all 4 references for 401037

  3. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897869 : Doi, Imai, Kressler, Yagita, Agata, Vooijs, Hamazaki, Inoue, Minato: Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia. in Scientific reports 2015 (PubMed)
    Show all 4 references for 4897869

  4. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897868 : Gibb, Saleem, Kang, Subler, Conrad: ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 2 references for 4897868

  5. Human Polyclonal ADAM10 Primary Antibody for IF (p), IHC (p) - ABIN701020 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. in Gene 2015 (PubMed)

  6. Human Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897866 : Nygaard, Pallister, Zurek, Voyich: The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300. in Journal of leukocyte biology 2013 (PubMed)

More Antibodies against ADAM10 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. these results show that ADAM10-Notch (show NOTCH1 Antibodies) signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  2. Findings provide evidence that ADAM10, and not ADAM17 (show ADAM17 Antibodies), is indispensable for proper retinal development as a regulator of NOTCH (show NOTCH1 Antibodies) signaling.

  3. this study shows that during positive selection in the spleen, B-cell receptor signaling causes immature type 1 transitional B cells to become receptive to Notch (show NOTCH1 Antibodies) ligands via Taok3 (show TAOK3 Antibodies)-mediated surface expression of ADAM10

  4. Thus, Leda-1/Pianp (show C12orf53 Antibodies) is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  5. ADAM10 was dispensable for alpha-toxin (show PLC Antibodies)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (show PLC Antibodies) attack on the plasma membrane was confirmed.

  6. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  7. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  8. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (show NOTCH1 Antibodies) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (show DCX Antibodies) expression

  9. our data afford the new insight that miR (show MLXIP Antibodies)-103a inhibited abdominal aortic aneurysm (AAA (show AAAS Antibodies)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (show AAAS Antibodies).

  10. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Regulation of ADAM10 by the TspanC8 subgroup of tetraspanins, namely Tspan5 (show TSPAN5 Antibodies), 10, 14, 15, 17 and 33 is reviewed.

  2. active ADAM10 form marks cancer stem-like cells with active Notch (show NOTCH1 Antibodies) signaling, known to mediate chemoresistance.

  3. Data show that tetraspanin 33 (tspan33 (show TSPAN33 Antibodies)) is an early activation marker, and that disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) protein expression does not correlate with Tspan33 (show TSPAN33 Antibodies) expression in B cells.

  4. High ADAM10 expression is associated with metastasis of hepatocellular carcinoma.

  5. The dysregulation of ADAM10, Fas (show FAS Antibodies) and FasL (show FASL Antibodies) could be useful indicators of the progression and severity of OSCC.

  6. 1,25D3 causes ectodomain shedding of TLR4 (show TLR4 Antibodies) and thereby decreases the responsiveness of cells to LPS (show IRF6 Antibodies). ADAM10, activated by extracellular Ca2 (show CA2 Antibodies)+ influx, was implicated in the ectodomain cleavage of TLR4 (show TLR4 Antibodies).

  7. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  8. Pre-incubation with simvastatin prior to treatment with IL-1beta (show IL1B Antibodies) + Oncostatin M (show OSM Antibodies) decreased the level of CD44 (show CD44 Antibodies) fragmentation, decreased the proportion of CD44 (show CD44 Antibodies) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (show CD44 Antibodies) and ADAM10.

  9. ADAM17 (show ADAM17 Antibodies) and ADAM10 cleave Nectin-4 (show PVRL4 Antibodies) and release soluble Nectin-4 (show PVRL4 Antibodies) (sN4).

  10. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (show AXL Antibodies)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (show ADAM17 Antibodies)) inhibition.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (show EFNB2 Antibodies) protein levels on the absence of flotillin-1 (show FLOT1 Antibodies) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (show ADAM8 Antibodies) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (show APLP2 Antibodies) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 Antigen Profile

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) antibody
  • ADAM metallopeptidase domain 10 (ADAM10) antibody
  • ADAM metallopeptidase domain 10 (LOC100219653) antibody
  • ADAM metallopeptidase domain 10 (Adam10) antibody
  • a disintegrin and metallopeptidase domain 10 (Adam10) antibody
  • ADAM metallopeptidase domain 10 (adam10) antibody
  • ADAM10 (LOC100101614) antibody
  • 1700031C13Rik antibody
  • ad10 antibody
  • ADAM-10 antibody
  • ADAM 10 antibody
  • Adam10 antibody
  • cd156c antibody
  • HsT18717 antibody
  • kuz antibody
  • kuzbanian antibody
  • LOC100219653 antibody
  • madm antibody
  • wu:fc03d12 antibody
  • xadam10 antibody

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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