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Browse our anti-ADAM10 (ADAM10) Antibodies

Full name:
anti-ADAM Metallopeptidase Domain 10 Antibodies (ADAM10)
On www.antibodies-online.com are 136 ADAM Metallopeptidase Domain 10 (ADAM10) Antibodies from 30 different suppliers available. Additionally we are shipping ADAM10 Kits (39) and ADAM10 Proteins (21) and many more products for this protein. A total of 200 ADAM10 products are currently listed.
Synonyms:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
list all antibodies Gene Name GeneID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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Most Popular Reactivities for anti-ADAM10 (ADAM10) Antibodies

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anti-Mouse (Murine) ADAM10 Antibodies:

anti-Human ADAM10 Antibodies:

anti-Rat (Rattus) ADAM10 Antibodies:

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Top referenced anti-ADAM10 Antibodies

  1. Cow (Bovine) Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN401037 : Rosendahl, Ko, Long, Brewer, Rosenzweig, Hedl, Anderson, Pyle, Moreland, Meyers, Kohno, Lyons, Lichenstein: Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for ABIN401037

  2. Human Polyclonal ADAM10 Primary Antibody for WB - ABIN264988 : Pan, Rubin: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. in Cell 1997 (PubMed)
    Show all 4 references for ABIN264988

  3. Human Monoclonal ADAM10 Primary Antibody for ELISA, WB - ABIN2656946 : Endres, Fahrenholz: Upregulation of the alpha-secretase ADAM10--risk or reason for hope? in The FEBS journal 2010 (PubMed)
    Show all 4 references for ABIN2656946

  4. Human Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN499211 : Qi, Rand, Wu, Sestan, Wang, Rakic, Xu, Artavanis-Tsakonas: Processing of the notch ligand delta by the metalloprotease Kuzbanian. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 4 references for ABIN499211

  5. Human Monoclonal ADAM10 Primary Antibody for FACS - ABIN2662460 : Mochizuki, Okada: ADAMs in cancer cell proliferation and progression. in Cancer science 2007 (PubMed)
    Show all 4 references for ABIN2662460

  6. Human Polyclonal ADAM10 Primary Antibody for IF (p), IHC (p) - ABIN701020 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. in Gene 2015 (PubMed)

More Antibodies against ADAM10 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (show LRP1 Antibodies) in the brain and the clearance of Abeta (show APP Antibodies) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (show APP Antibodies) accumulation in the AD brain

  2. With a proteomic analysis of Adam10-deficient neurons the authors identified 91, mostly novel ADAM10 substrate candidates, making ADAM10 a major protease for membrane proteins in the nervous system.

  3. Data suggest that large extracellular loop of Tspan14 mediates interaction with ADAM10, promotes ADAM10 maturation/trafficking to cell surface, and affects ADAM10 substrate specificity; ADAM10/Tspan14 interact in platelets/vascular endothelial cells.

  4. findings underscore the role of ADAM10 as an indispensable component of Notch (show NOTCH1 Antibodies) signaling in SCs (show TWIST1 Antibodies) and for maintaining the SC pool

  5. established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 Antibodies) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10

  6. ADAM10 (and BACE1 (show BACE Antibodies)) are localized in synaptic vesicles in primary hippocampal neurons.

  7. B cell levels of ADAM10, specifically, are increased in allergic patients and Th2 prone WT mouse strains.

  8. This study demonstrated that a neuron-intrinsic function of ADAM10 in axonal regeneration.

  9. NG2 (show Vcan Antibodies) cleavage by ADAM10 yields an ectodomain present in the extracellular matrix and a C-terminal fragment that is subsequently further processed by the gamma-secretase to release an intracellular domain.

  10. These data suggest a critical role of Adam10 for leukocyte recruitment, inflammatory mediator production, and extracellular matrix degradation.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (show LRP1 Antibodies) in the brain and the clearance of Abeta (show APP Antibodies) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (show APP Antibodies) accumulation in the AD brain

  2. In response to trastuzumab, both HER3 (show ERBB3 Antibodies) and the metalloprotease (show ADAM8 Antibodies) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (show ERBB3 Antibodies) ligand heregulin (show NRG1 Antibodies) from the cell surface to activate HER3 (show ERBB3 Antibodies) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (show RYK Antibodies) signaling.

  3. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (show CDH1 Antibodies) activity.

  4. We now show that ADAM10 is critical for alpha-hemolysin (show PLC Antibodies)-mediated activation of the NLRP3 (show NLRP3 Antibodies) inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10-alpha-hemolysin (show PLC Antibodies) interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 on the cell surface.

  5. ADAM10 was overexpressed in the posterior band of sections from some patients with temporomandibular joint disk disorders.

  6. ADAM10 activity contributes to house dust mite-induced shedding of chemokines, including CCL20 (show CCL20 Antibodies)

  7. The results of this study demonistrated that age-dependent increase in ADAM10 levels and activity in platelets.

  8. The production of ADAM10-positive microvesicles from smoke-exposed neutrophils provides a novel molecular mechanism for the vastly accelerated risk of AAA (show APP Antibodies) in smokers.

  9. activated microRNA-494-targets Bmi1 (show BMI1 Antibodies) and ADAM10 by silibinin and ablates cancer stemness in head and neck squamous cell carcinomas

  10. These findings indicate that different mechanisms regulate shear- and ligand-induced shedding and shear forces found within the vasculature can regulate ADAM10 activity.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (show EFNB2 Antibodies) protein levels on the absence of flotillin-1 (show FLOT1 Antibodies) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (show ADAM8 Antibodies) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (show APLP2 Antibodies) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 Antigen Profile

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) antibody
  • ADAM metallopeptidase domain 10 (ADAM10) antibody
  • ADAM metallopeptidase domain 10 (LOC100219653) antibody
  • ADAM metallopeptidase domain 10 (Adam10) antibody
  • a disintegrin and metallopeptidase domain 10 (Adam10) antibody
  • ADAM metallopeptidase domain 10 (adam10) antibody
  • ADAM10 (LOC100101614) antibody
  • 1700031C13Rik antibody
  • ad10 antibody
  • ADAM-10 antibody
  • ADAM 10 antibody
  • Adam10 antibody
  • cd156c antibody
  • HsT18717 antibody
  • kuz antibody
  • kuzbanian antibody
  • LOC100219653 antibody
  • madm antibody
  • wu:fc03d12 antibody
  • xadam10 antibody

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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