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Browse our ADAM10 (ADAM10) ELISA Kits

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ADAM Metallopeptidase Domain 10 ELISA Kits (ADAM10)
On are 43 ADAM Metallopeptidase Domain 10 (ADAM10) ELISA Kits from 12 different suppliers available. Additionally we are shipping ADAM10 Antibodies (142) and ADAM10 Proteins (20) and many more products for this protein. A total of 209 ADAM10 products are currently listed.
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
list all ELISA KIts Gene Name GeneID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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Top referenced ADAM10 ELISA Kits

  1. Human ADAM10 ELISA Kit for Sandwich ELISA - ABIN414771 : Van Crombruggen, Holtappels, De Ruyck, Derycke, Tomassen, Bachert: RAGE processing in chronic airway conditions: involvement of Staphylococcus aureus and ECP. in The Journal of allergy and clinical immunology 2012 (PubMed)
    Show all 3 references for ABIN414771

More ELISA Kits for ADAM10 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. this study shows that during positive selection in the spleen, B-cell receptor signaling causes immature type 1 transitional B cells to become receptive to Notch (show NOTCH1 ELISA Kits) ligands via Taok3 (show TAOK3 ELISA Kits)-mediated surface expression of ADAM10

  2. Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  3. ADAM10 was dispensable for alpha-toxin (show PLC ELISA Kits)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (show PLC ELISA Kits) attack on the plasma membrane was confirmed.

  4. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  5. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  6. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (show NOTCH1 ELISA Kits) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (show DCX ELISA Kits) expression

  7. our data afford the new insight that miR (show MLXIP ELISA Kits)-103a inhibited abdominal aortic aneurysm (AAA (show AAAS ELISA Kits)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (show AAAS ELISA Kits).

  8. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

  9. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (show AXL ELISA Kits)kinase (Axl) in lupus-prone leukocytes.

  10. Loss of ADAM10 in murine liver results in hepatocyte necrosis and concomitant liver fibrosis. ADAM10 directly regulates expression of bile acid transporters but is dispensable for Notch2 (show NOTCH2 ELISA Kits)-dependent formation of the biliary system. Differentiation of liver progenitor cells to hepatocytes is augmented in the absence of ADAM10.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. 1,25D3 causes ectodomain shedding of TLR4 (show TLR4 ELISA Kits) and thereby decreases the responsiveness of cells to LPS (show IRF6 ELISA Kits). ADAM10, activated by extracellular Ca2 (show CA2 ELISA Kits)+ influx, was implicated in the ectodomain cleavage of TLR4 (show TLR4 ELISA Kits).

  2. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  3. Pre-incubation with simvastatin prior to treatment with IL-1beta (show IL1B ELISA Kits) + Oncostatin M (show OSM ELISA Kits) decreased the level of CD44 (show CD44 ELISA Kits) fragmentation, decreased the proportion of CD44 (show CD44 ELISA Kits) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (show CD44 ELISA Kits) and ADAM10.

  4. ADAM17 (show ADAM17 ELISA Kits) and ADAM10 cleave Nectin-4 (show PVRL4 ELISA Kits) and release soluble Nectin-4 (show PVRL4 ELISA Kits) (sN4).

  5. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (show AXL ELISA Kits)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (show ADAM17 ELISA Kits)) inhibition.

  6. we found that ADAM10 expression was associated with a more rapid metastatic progression confirming its role in uveal melanoma metastasis.

  7. the TLR4 (show TLR4 ELISA Kits)/Gal-1 (show LGALS1 ELISA Kits) signaling pathway regulates lactate-mediated EMT (show ITK ELISA Kits) processes through the activation of ADAM10 and ADAM17 (show ADAM17 ELISA Kits) in colon cancer cells.

  8. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (show LRP1 ELISA Kits) in the brain and the clearance of Abeta (show APP ELISA Kits) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (show APP ELISA Kits) accumulation in the AD brain

  9. In response to trastuzumab, both HER3 (show ERBB3 ELISA Kits) and the metalloprotease (show ADAM8 ELISA Kits) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (show ERBB3 ELISA Kits) ligand heregulin (show NRG1 ELISA Kits) from the cell surface to activate HER3 (show ERBB3 ELISA Kits) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (show RYK ELISA Kits) signaling.

  10. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (show CDH1 ELISA Kits) activity.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (show EFNB2 ELISA Kits) protein levels on the absence of flotillin-1 (show FLOT1 ELISA Kits) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (show ADAM8 ELISA Kits) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (show APLP2 ELISA Kits) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 Antigen Profile

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) Elisa Kit
  • ADAM metallopeptidase domain 10 (ADAM10) Elisa Kit
  • ADAM metallopeptidase domain 10 (LOC100219653) Elisa Kit
  • ADAM metallopeptidase domain 10 (Adam10) Elisa Kit
  • a disintegrin and metallopeptidase domain 10 (Adam10) Elisa Kit
  • ADAM metallopeptidase domain 10 (adam10) Elisa Kit
  • ADAM10 (LOC100101614) Elisa Kit
  • 1700031C13Rik Elisa Kit
  • ad10 Elisa Kit
  • ADAM-10 Elisa Kit
  • ADAM 10 Elisa Kit
  • Adam10 Elisa Kit
  • cd156c Elisa Kit
  • HsT18717 Elisa Kit
  • kuz Elisa Kit
  • kuzbanian Elisa Kit
  • LOC100219653 Elisa Kit
  • madm Elisa Kit
  • wu:fc03d12 Elisa Kit
  • xadam10 Elisa Kit

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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