You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our ADAM10 Proteins (ADAM10)

Full name:
ADAM Metallopeptidase Domain 10 Proteins (ADAM10)
On www.antibodies-online.com are 21 ADAM Metallopeptidase Domain 10 (ADAM10) Proteins from 10 different suppliers available. Additionally we are shipping ADAM10 Antibodies (127) and ADAM10 Kits (47) and many more products for this protein. A total of 199 ADAM10 products are currently listed.
Synonyms:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
list all proteins Gene Name GeneID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

Show all synonyms

ADAM10 Proteins (ADAM10) by Origin

Select your origin of interest

More Proteins for ADAM10 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data suggest that large extracellular loop of Tspan14 mediates interaction with ADAM10, promotes ADAM10 maturation/trafficking to cell surface, and affects ADAM10 substrate specificity; ADAM10/Tspan14 interact in platelets/vascular endothelial cells.

  2. findings underscore the role of ADAM10 as an indispensable component of Notch (show NOTCH1 Proteins) signaling in SCs (show TWIST1 Proteins) and for maintaining the SC pool

  3. established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 Proteins) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10

  4. ADAM10 (and BACE1 (show BACE Proteins)) are localized in synaptic vesicles in primary hippocampal neurons.

  5. B cell levels of ADAM10, specifically, are increased in allergic patients and Th2 prone WT mouse strains.

  6. This study demonstrated that a neuron-intrinsic function of ADAM10 in axonal regeneration.

  7. NG2 (show Vcan Proteins) cleavage by ADAM10 yields an ectodomain present in the extracellular matrix and a C-terminal fragment that is subsequently further processed by the gamma-secretase to release an intracellular domain.

  8. These data suggest a critical role of Adam10 for leukocyte recruitment, inflammatory mediator production, and extracellular matrix degradation.

  9. Results indicate peroxisome proliferator-activated receptor alpha (PPARalpha (show PPARA Proteins)) as an important factor regulating neuronal a disintegrin and metalloproteinase 10 ADAM10 expression and, thus, alpha-secretase proteolysis of amyloid precursor protein (APP (show APP Proteins)).

  10. In mouse retinas, ADAM10 or gamma-secretase inhibition induced vascular sprouting and density in vivo, whereas attenuation of both ADAM10 and ADAM17 (show ADAM17 Proteins) activity produced the opposite phenotype.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. The production of ADAM10-positive microvesicles from smoke-exposed neutrophils provides a novel molecular mechanism for the vastly accelerated risk of AAA (show APP Proteins) in smokers.

  2. activated microRNA-494-targets Bmi1 (show BMI1 Proteins) and ADAM10 by silibinin and ablates cancer stemness in head and neck squamous cell carcinomas

  3. These findings indicate that different mechanisms regulate shear- and ligand-induced shedding and shear forces found within the vasculature can regulate ADAM10 activity.

  4. Data suggest that large extracellular loop of Tspan14 mediates interaction with ADAM10, promotes ADAM10 maturation/trafficking to cell surface, and affects ADAM10 substrate specificity; ADAM10/Tspan14 interact in platelets/vascular endothelial cells.

  5. Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

  6. that miR (show MLXIP Proteins)-140-5p suppresses tumor migration and invasion by inhibiting ADAM10-mediated Notch1 (show NOTCH1 Proteins) signaling pathway

  7. Our findings hinted that overexpression of ADAM10 promotes the progression and migration of nasopharyngeal carcinoma

  8. Pro- and active-ADAM10 expression were significantly increased in preeclamptic placentas and inversely correlated to H2S production enzymes cystathionine beta-synthase (show CBS Proteins) and cystathionine gamma-lyase (show CTH Proteins) expression

  9. Serum ADAM10 level was increased in type 1 diabetes and was a significant determinant of circulating cRAGE

  10. ADAM10 gene expression is down-regulated in platelets of Alzheimer's disease patients.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (show EFNB2 Proteins) protein levels on the absence of flotillin-1 (show FLOT1 Proteins) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (show ADAM8 Proteins) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (show APLP2 Proteins) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 Protein Profile

Protein Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a)
  • ADAM metallopeptidase domain 10 (ADAM10)
  • ADAM metallopeptidase domain 10 (LOC100219653)
  • ADAM metallopeptidase domain 10 (Adam10)
  • a disintegrin and metallopeptidase domain 10 (Adam10)
  • ADAM metallopeptidase domain 10 (adam10)
  • ADAM10 (LOC100101614)
  • 1700031C13Rik protein
  • ad10 protein
  • ADAM-10 protein
  • ADAM 10 protein
  • Adam10 protein
  • cd156c protein
  • HsT18717 protein
  • kuz protein
  • kuzbanian protein
  • LOC100219653 protein
  • madm protein
  • wu:fc03d12 protein
  • xadam10 protein

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
Selected quality suppliers for ADAM10 Proteins (ADAM10)
Did you look for something else?