Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Mib and Mib2 interact with Fih-1 that is involved in the hypoxia signaling pathway.
Zebrafish Mib and Mib2 are colocalized in transfected cells and function redundantly in regulating Notch (show NOTCH1 ELISA Kits) signaling in embryos.
Missense p.V742G variant in MIB2 is associated with left ventricle hypertrabeculation/non-compaction and Menetrier-like gastropathy.
Here, we report a novel interaction between CYLD (show CYLD ELISA Kits) and MIB2 that supports the hypothesis that the CYLD (show CYLD ELISA Kits)/MIB2 interaction might play a pathogenic role in human cancer.
The DLAIS motif in MAVS (show MAVS ELISA Kits) was found to be critical for MIB2 binding, the ligation of K63-linked ubiquitin to TANK-binding kinase 1 (show TBK1 ELISA Kits), and phosphorylation-mediated IRF3 (show IRF3 ELISA Kits)/7 activation.
identify MIB2 as a novel component of the activated BCL10 (show BCL10 ELISA Kits) signaling complex and a missing link in the BCL10 (show BCL10 ELISA Kits)-dependent NF-kappaB (show NFKB1 ELISA Kits) signaling pathway.
Mib2 has functional similarities to Mib1, but might have distinct roles in Notch signaling as an E3 ubiquitin ligase
Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma.
skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 (show JAG2 ELISA Kits) and is aberrantly overexpressed in multiple myeloma cells.
skeletrophin might be a novel suppressor factor for melanoma invasion
Data identify Mind bomb-2 as an E3 ubiquitin ligase that interacts with and ubiquitinates the NR2B (show GRIN2B ELISA Kits) subunit of the NMDAR (show GRIN1 ELISA Kits) in mammalian cells.
created a targeted mutation of Mib2 and show that its phenotype is a variable penetrance, failure to close the cranial neural tube
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).
E3 ubiquitin-protein ligase MIB2
, mind bomb homolog 2
, mindbomb homolog 2
, novel zinc finger protein
, putative NF-kappa-B-activating protein 002N
, zinc finger ZZ type with ankyrin repeat domain protein 1
, zinc finger, ZZ type with ankyrin repeat domain 1
, RBSC-skeletrophin/dystrophin-like polypeptide
, dystrophin-like protein
, mind bomb-2