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Browse our Mindbomb E3 Ubiquitin Protein Ligase 2 Proteins (MIB2)

Full name:
Mindbomb E3 Ubiquitin Protein Ligase 2 Proteins (MIB2)
On www.antibodies-online.com are 9 Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2) Proteins from 4 different suppliers available. Additionally we are shipping Mindbomb E3 Ubiquitin Protein Ligase 2 Antibodies (28) and Mindbomb E3 Ubiquitin Protein Ligase 2 Kits (4) and many more products for this protein. A total of 42 Mindbomb E3 Ubiquitin Protein Ligase 2 products are currently listed.
Synonyms:
2210008I11Rik, skd, Zzank1, ZZZ5
list all proteins Gene Name GeneID UniProt
MIB2 142678 Q96AX9
MIB2 474147  
MIB2 76580 Q8R516

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Mindbomb E3 Ubiquitin Protein Ligase 2 Proteins (MIB2) by Origin

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More Proteins for Mindbomb E3 Ubiquitin Protein Ligase 2 Interaction Partners

Zebrafish Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2) interaction partners

  1. Mib and Mib2 interact with Fih-1 that is involved in the hypoxia signaling pathway.

  2. Zebrafish Mib and Mib2 are colocalized in transfected cells and function redundantly in regulating Notch (show NOTCH1 Proteins) signaling in embryos.

Human Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2) interaction partners

  1. Here, we report a novel interaction between CYLD (show CYLD Proteins) and MIB2 that supports the hypothesis that the CYLD (show CYLD Proteins)/MIB2 interaction might play a pathogenic role in human cancer.

  2. The DLAIS motif in MAVS (show MAVS Proteins) was found to be critical for MIB2 binding, the ligation of K63-linked ubiquitin to TANK-binding kinase 1 (show TBK1 Proteins), and phosphorylation-mediated IRF3 (show IRF3 Proteins)/7 activation.

  3. identify MIB2 as a novel component of the activated BCL10 (show BCL10 Proteins) signaling complex and a missing link in the BCL10 (show BCL10 Proteins)-dependent NF-kappaB (show NFKB1 Proteins) signaling pathway.

  4. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch (show NOTCH1 Proteins) signaling as an E3 ubiquitin ligase (show MUL1 Proteins)

  5. Skeletrophin, a novel RING molecule controlled by the chromatin remodeling complex, is down-regulated in melanoma.

  6. skeletrophin is a novel ubiquitin ligase that targets the intracellular region of Jagged-2 (show JAG2 Proteins) and is aberrantly overexpressed in multiple myeloma cells.

  7. skeletrophin might be a novel suppressor factor for melanoma invasion

  8. Data identify Mind bomb-2 as an E3 ubiquitin ligase (show MUL1 Proteins) that interacts with and ubiquitinates the NR2B (show GRIN2B Proteins) subunit of the NMDAR (show GRIN1 Proteins) in mammalian cells.

Mouse (Murine) Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2) interaction partners

  1. identify MIB2 as a novel component of the activated BCL10 (show BCL10 Proteins) signaling complex and a missing link in the BCL10 (show BCL10 Proteins)-dependent NF-kappaB (show NFKB1 Proteins) signaling pathway.

  2. Mib2 has functional similarities to Mib1, but might have distinct roles in Notch (show NOTCH1 Proteins) signaling as an E3 ubiquitin ligase (show MUL1 Proteins)

  3. created a targeted mutation of Mib2 and show that its phenotype is a variable penetrance, failure to close the cranial neural tube

Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2) Protein Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).

Alternative names and synonyms associated with Mindbomb E3 Ubiquitin Protein Ligase 2 (MIB2)

  • mind bomb 2 (mib2)
  • mindbomb E3 ubiquitin protein ligase 2 (MIB2)
  • mindbomb E3 ubiquitin protein ligase 2 (Mib2)
  • mindbomb homolog 2 (Drosophila) (Mib2)
  • 2210008I11Rik protein
  • skd protein
  • Zzank1 protein
  • ZZZ5 protein

Protein level used designations for MIB2

E3 ubiquitin-protein ligase MIB2 , miblike , mind bomb homolog 2 , mindbomb homolog 2 , novel zinc finger protein , novelzin , putative NF-kappa-B-activating protein 002N , skeletrophin , zinc finger ZZ type with ankyrin repeat domain protein 1 , zinc finger, ZZ type with ankyrin repeat domain 1 , RBSC-skeletrophin , RBSC-skeletrophin/dystrophin-like polypeptide , dyslike , dystrophin-like protein , mind bomb-2

GENE ID SPECIES
560887 Danio rerio
142678 Homo sapiens
419408 Gallus gallus
474147 Rattus norvegicus
76580 Mus musculus
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