Browse our NEDD4 (NEDD4) ELISA Kits

Full name:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase ELISA Kits (NEDD4)
On www.antibodies-online.com are 0 Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4) ELISA Kits from different suppliers available. Additionally we are shipping NEDD4 Antibodies (80) and NEDD4 Proteins (5) and many more products for this protein. A total of 89 NEDD4 products are currently listed.
Synonyms:
AA959633, AL023035, AU019897, CG7555, CG32184, CG42279, Dmel\\CG42279, Dmel_CG7555, Dmel_CG32184, dNedd4, dNedd4-1, E430025J12Rik, GB16853, mKIAA0093, Nedd4, Nedd4-1, Nedd4a, RPF1
list all ELISA KIts Gene Name GeneID UniProt
Human NEDD4 NEDD4 4734 P46934
Mouse NEDD4 NEDD4 17999 P46935
Rat NEDD4 NEDD4 25489 Q62940

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More ELISA Kits for NEDD4 Interaction Partners

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4) interaction partners

  1. NPM1 (show GJA1 ELISA Kits)-dependent nucleolar PIDDosome is a key initiator of the caspase-2 (show CASP2 ELISA Kits) activation cascade.

  2. these results suggest that Nedd4 suppresses colonic WNT (show WNT2 ELISA Kits) signaling and tumor growth, at least in part, by suppressing the transcription factors LEF1 (show LEF1 ELISA Kits) and YY1 (show YY1 ELISA Kits).

  3. Findings indicate that reducing Nedd4 protein by 50% significantly impairs long-term potentiation and long-term memory thereby demonstrating an important role for Nedd4 in these processes.

  4. Upregulation of long non-coding RNA PAPAS (show PSTPIP1 ELISA Kits) in response to hypoosmotic stress does not increase H4K20me3 because of Nedd4-dependent ubiquitinylation and proteasomal degradation of Suv4-20h2 (show SUV420H2 ELISA Kits).

  5. we propose that Nedd4 functions as a novel Pax7 (show PAX7 ELISA Kits) regulator, which activity is temporally and spatially controlled to modulate the Pax7 (show PAX7 ELISA Kits) protein levels and therefore satellite cell fate.

  6. PDLIM7 (show PDLIM7 ELISA Kits) is a bona fide skeletal muscle substrate of Nedd4-1.

  7. show that absence of Nedd4 in pre-osteoblasts results in decreased cell proliferation and altered osteogenic differentiation

  8. Nedd4 overexpression accelerates zebrafis (show IRS2 ELISA Kits)h embryonic growth through IRS-2 in vivo.

  9. Nedd4 co-injection was found to have no affect on Gag- or Env-specific IFNgamma but had a trend of increased Gag-specific IL-6, IL-17A and TNFalpha that was not seen following Env stimulation.

  10. NEDD4 is a previously unknown component of the CD40 (show CD40 ELISA Kits) signalling complex necessary for AKT (show AKT1 ELISA Kits) activation.

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4) interaction partners

  1. Our results reveal a novel mechanism of upregulation of NEDD4 expression in pancreatic adenocarcinoma

  2. Describe an autoinhibitory mechanism for NEDD4-1 ubiquitin ligase involving a linker-HECT domain interaction. This intramolecular interaction traps the HECT enzyme in its inactive state and can be relieved by linker phosphorylation.

  3. Insights into links between autophagy and the ubiquitin system showed that LC3B-binding can steer intrinsic NEDD4 E3 ligase activity.

  4. NEDD4-1 recognizes SERTA domain containing proline rich region of p34SEI-1. Residues of NEDD4-1 responsible for direct interaction with p34SEI-1 are identified by NMR titration experiments.

  5. Our results demonstrate that NEDD4 may promote the acquired resistance of non-small-cell lung cancer cells to erlotinib by decreasing phosphatase and tensin homolog deleted on chromosome 10 protein expression. Targeted decrease in NEDD4 expression may be a potential therapeutic strategy for tyrosine kinase (show TXK ELISA Kits) inhibitor-resistant non-small-cell lung cancer.

  6. this is the first demonstration that Nedd4-1 regulates hOAT1 (show SLC22A6 ELISA Kits) ubiquitination, expression, and transport activity through its WW2 and WW3 domains

  7. both Nedd4-1 and Nedd4-2 are important regulators for hOAT1 (show SLC22A6 ELISA Kits) ubiquitination, expression, and function

  8. Nedd4-1 inhibited Rap2a (show RAP2A ELISA Kits) activity, and promoted the migration and invasion of glioma cells.

  9. We concluded that USP15 (show USP15 ELISA Kits) attenuates IGF-I (show IGF1 ELISA Kits) signaling by antagonizing Nedd4-induced IRS-2 (show IRS2 ELISA Kits) ubiquitination.

  10. Data suggest a possible molecular mechanism might be that NEDD4 silence led to an increase in PTEN (phosphatase and tensin (show TNS1 ELISA Kits) homologue) expression.

NEDD4 Antigen Profile

Antigen Summary

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Involved in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19193720). Predominantly involved in ubiquitination of membrane bound forms of ERBB4 rather than processed precursors and intermediate membrane-anchored 80 kDa fragments (m80HER4), with a lesser role in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19047365). Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2 (By similarity).

Alternative names and synonyms associated with NEDD4

  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (NEDD4) Elisa Kit
  • neural precursor cell expressed, developmentally down-regulated 4 (Nedd4) Elisa Kit
  • CG42279 gene product from transcript CG42279-RJ (Nedd4) Elisa Kit
  • E3 ubiquitin-protein ligase Nedd-4 (Nedd4) Elisa Kit
  • neural precursor cell expressed, developmentally down-regulated 4 (NEDD4) Elisa Kit
  • neural precursor cell expressed, developmentally down-regulated 4 (nedd4) Elisa Kit
  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (Nedd4) Elisa Kit
  • AA959633 Elisa Kit
  • AL023035 Elisa Kit
  • AU019897 Elisa Kit
  • CG7555 Elisa Kit
  • CG32184 Elisa Kit
  • CG42279 Elisa Kit
  • Dmel\\CG42279 Elisa Kit
  • Dmel_CG7555 Elisa Kit
  • Dmel_CG32184 Elisa Kit
  • dNedd4 Elisa Kit
  • dNedd4-1 Elisa Kit
  • E430025J12Rik Elisa Kit
  • GB16853 Elisa Kit
  • mKIAA0093 Elisa Kit
  • Nedd4 Elisa Kit
  • Nedd4-1 Elisa Kit
  • Nedd4a Elisa Kit
  • RPF1 Elisa Kit

Protein level used designations for NEDD4

E3 ubiquitin-protein ligase NEDD4 , NEDD-4 , cell proliferation-inducing gene 53 protein , neural precursor cell expressed developmentally down-regulated protein 4 , receptor-potentiating factor 1 , neural precursor cell expressed, developmentally down-regulated gene 4 , neural precursor cell expressed, developmentally down-regulated gene 4a , neural precursor cell expressed, developmentally down-regulted gene 4 , CG42279-PE , CG42279-PF , CG42279-PG , CG42279-PH , CG42279-PI , CG42279-PJ , CG42279-PK , CG42279-PL , CG42279-PM , DNedd4 , Nedd4-PE , Nedd4-PF , Nedd4-PG , Nedd4-PH , Nedd4-PI , Nedd4-PJ , Nedd4-PK , Nedd4-PL , Nedd4-PM , neural precursor cell expressed, developmentally down-regulated 4 , ubiquitin-protein ligase Nedd4 , E3 ubiquitin-protein ligase NEDD4-like , e3 ubiquitin-protein ligase NEDD4-like , neural precursor cell expressed, developmentally down-regulated gene 4A

GENE ID SPECIES
4734 Homo sapiens
17999 Mus musculus
39958 Drosophila melanogaster
411723 Apis mellifera
415406 Gallus gallus
467689 Pan troglodytes
507781 Bos taurus
608738 Canis lupus familiaris
699550 Macaca mulatta
100009418 Oryctolagus cuniculus
100054735 Equus caballus
100083335 Ornithorhynchus anatinus
100115069 Nasonia vitripennis
100152466 Sus scrofa
100223530 Taeniopygia guttata
100386326 Callithrix jacchus
100457150 Pongo abelii
100496333 Xenopus (Silurana) tropicalis
100547485 Meleagris gallopavo
100600829 Nomascus leucogenys
25489 Rattus norvegicus
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