Browse our POFUT1 Proteins (POFUT1)

Full name:
Protein O-Fucosyltransferase 1 Proteins (POFUT1)
On are 11 Protein O-Fucosyltransferase 1 (POFUT1) Proteins from 6 different suppliers available. Additionally we are shipping POFUT1 Antibodies (65) and POFUT1 Kits (6) and many more products for this protein. A total of 90 POFUT1 products are currently listed.
DDD2, Fut12, mKIAA0180, O-Fuc-T, O-FucT-1, O-FUT, OFUCT1, pofut1, zgc:110472
list all proteins Gene Name GeneID UniProt
POFUT1 23509 Q9H488
POFUT1 140484 Q91ZW2
POFUT1 311551 Q6EV70

Show all synonyms

POFUT1 Proteins (POFUT1) by Origin

Select your origin of interest

Top referenced POFUT1 Proteins

  1. Human POFUT1 Protein expressed in Escherichia coli (E. coli) - ABIN1098747 : Luo, Haltiwanger: O-fucosylation of notch occurs in the endoplasmic reticulum. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for 1098747

More Proteins for POFUT1 Interaction Partners

Human Protein O-Fucosyltransferase 1 (POFUT1) interaction partners

  1. Our findings suggested that overexpression of Pofut1 and activated Notch1 (show NOTCH1 Proteins) signaling may be associated with a poor prognosis in breast cancer.

  2. POFUT1 gene expression in gastric cancer

  3. POFUT1, POGLUT1 (show POGLUT1 Proteins) and ADAM10 (show ADAM10 Proteins) are processing enzymes that are involved in different steps of Notch (show NOTCH1 Proteins) receptor activation in the epidermis[10]; the roles of these unique enzymes in a single pathway may explain both the overlapping and distinct clinical features of DDD (show KRT5 Proteins) and RAK (show FRK Proteins) patients

  4. High expression of POFUT1 correlates with aggressive clinicopathological characteristics and poor prognosis of hepatocellular carcinoma patients.

  5. The upregulation of poFUT1 by LIF (show LIF Proteins) facilitated trophoblast cell migration and invasion through activating the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling pathway.

  6. Silencing of Pofut1 expression exerted antiproliferative and antiadhesive effects on hepatocytes.

  7. Only a novel 1-bp deletion (c.246+5delG) in POFUT1 was found in a Chinese family with Dowling-Degos disease (DDD (show KRT5 Proteins)). No other novel mutation or this deletion was detected in POFUT1 in a second DDD (show KRT5 Proteins) family and a sporadic DDD (show KRT5 Proteins) case by Sanger Sequencing.

  8. Identification of six pathogenic POFUT1 mutations in Dowling-Degos disease patients of different ethnic origin.

  9. POFUT1 expression can contribute to cancer progression and that POFUT1 may serve as a diagnostic marker and a therapeutic target for OSCCs.

  10. The protein product of POFUT1 plays a significant and conserved role in melanin synthesis and transport.

Mouse (Murine) Protein O-Fucosyltransferase 1 (POFUT1) interaction partners

  1. The POFUT1 binds EGF (show EGF Proteins)-like domains of the hEGF type and that the highly correlated presence of POFUT1 and fucosylatable hEGFs has accompanied animal evolution.

  2. Loss of Pofut1 expression is associated with Muscle Aging-Related Phenotypes.

  3. results demonstrated that POFUT1-mediated O-fucosylation of NOTCH (show NOTCH1 Proteins) receptors regulates myogenic cell differentiation and affects postnatal muscle growth in mice

  4. results establish the critical role of Pofut1 on Notch (show NOTCH1 Proteins) pathway activation during myogenic differentiation

  5. mDLL1 O-fucosylation by POFUT1 is dispensable for ligand function

  6. Loss of Pofut1 is associated with myeloid hyperplasia and impaired lymphopoiesis.

  7. Pofut1 and O-fucose have roles in mammalian Notch (show NOTCH1 Proteins) signaling

  8. Pofut1 is required for Notch (show NOTCH1 Proteins) signaling upstream of NICD1.

  9. These data are consistent with a role for Pofut1 in AChR aggregation during synaptogenesis via the regulation of the synaptogenic activity of muscle agrin (show AGRN Proteins).

  10. Reduced POFUT1 levels might affect Notch (show NOTCH1 Proteins) trafficking or overall O-fucosylation.

POFUT1 Protein Profile

Protein Summary

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Alternative names and synonyms associated with POFUT1

  • protein O-fucosyltransferase 1 (POFUT1)
  • protein O-fucosyltransferase 1 (pofut1)
  • protein O-fucosyltransferase 1 (Pofut1)
  • DDD2 protein
  • Fut12 protein
  • mKIAA0180 protein
  • O-Fuc-T protein
  • O-FucT-1 protein
  • O-FUT protein
  • OFUCT1 protein
  • pofut1 protein
  • zgc:110472 protein

Protein level used designations for POFUT1

GDP-fucose protein O-fucosyltransferase 1 , putative protein-O-fucosyltransferase , O-FucT-1 , peptide-O-fucosyltransferase 1 , protein-O-fucosyltransferase 1 , protein-O-fucosyltransferase , protein O-fucosyltransferase 1 , o-fucosyltransferase protein

395070 Gallus gallus
397627 Sus scrofa
403029 Danio rerio
449504 Pan troglodytes
496411 Xenopus (Silurana) tropicalis
589493 Strongylocentrotus purpuratus
609881 Canis lupus familiaris
100125467 Oryzias latipes
100294553 Pongo abelii
23509 Homo sapiens
140484 Mus musculus
311551 Rattus norvegicus
Selected quality suppliers for POFUT1 Proteins (POFUT1)
Did you look for something else?