Browse our RBPJ (RBPJ) ELISA Kits

Full name:
Recombination Signal Binding Protein For Immunoglobulin kappa J Region ELISA Kits (RBPJ)
On www.antibodies-online.com are 0 Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) ELISA Kits from different suppliers available. Additionally we are shipping RBPJ Antibodies (86) and RBPJ Proteins (8) and many more products for this protein. A total of 100 RBPJ products are currently listed.
Synonyms:
AI843960, AOS3, CBF1, csl, Igkjrb, IGKJRB1, Igkrsbp, KBF2, RBP-J, RBP-J kappa, RBPjk, Rbpsuh, Su(H), SUH, XSu(H), xsu(h)1
list all ELISA KIts Gene Name GeneID UniProt
Rat RBPJ RBPJ 679028  
Human RBPJ RBPJ 3516 Q06330
Mouse RBPJ RBPJ 19664 P31266

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More ELISA Kits for RBPJ Interaction Partners

Human Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. RBPJ links MYC (show MYC ELISA Kits) and transcriptional control through CDK9 (show CDK9 ELISA Kits) in brain tumors, providing potential nodes of fragility for therapeutic intervention, potentially distinct from NOTCH (show NOTCH1 ELISA Kits)

  2. Mean CBF1 expression is significantly increased in isocitrate dehydrogenase 1 (IDH1 (show IDH1 ELISA Kits)) R132H mutant glioblastoma. Hypoxic regions of glioblastoma have higher CBF1 activation and exposure to low oxygen can induce its expression in glioma cells in vitro.

  3. structural and biophysical studies demonstrate that RITA (show ZNF331 ELISA Kits) binds RBP-J similarly to the RAM (show RAB27A ELISA Kits) (RBP-J-associated molecule) domain of Notch (show NOTCH1 ELISA Kits), our biochemical and cellular assays suggest that RITA (show ZNF331 ELISA Kits) interacts with additional regions in RBP-J.

  4. The present findings indicate that p53 (show TP53 ELISA Kits), in turn, decreases CSL expression, which can serve to enhance p53 (show TP53 ELISA Kits) activity in acute DNA damage response of cells.

  5. RBP-J mediated by miR (show MLXIP ELISA Kits)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  6. These results suggest that PSK (show TAOK2 ELISA Kits) suppresses Hedgehog (show SHH ELISA Kits) signaling through down-regulation of MAML3 and RBPJ transcription under hypoxia, inhibiting the induction of a malignant phenotype in pancreatic cancer. Our results may lead to development of new treatments for refractory pancreatic cancer using PSK (show TAOK2 ELISA Kits) as a Hedgehog (show SHH ELISA Kits) inhibitor

  7. our findings reconcile the 2 biological events and point to a multistep process of CAF (show KAT2B ELISA Kits) activation under convergent CSL and p53 (show TP53 ELISA Kits) control. Activation of p53 (show TP53 ELISA Kits) provides a failsafe mechanism against consequences of compromised CSL activity in stromal cells.

  8. RBPJ polymorphism [rs874040(CC) allele] skews memory T cells toward a pro-inflammatory phenotype involving Notch (show NOTCH1 ELISA Kits) signaling, thus increasing the susceptibility to develop rheumatoid arthritis.

  9. The role of CSL-dependent and independent Notch (show NOTCH1 ELISA Kits) signaling pathways in cell apoptosis is described in normal tissue homeostasis and in tumorigenesis. (Review)

  10. These results support a model in which EBNA2 and EBNA3s compete for distinct subsets of RBPJ sites to regulate cell genes and where EBNA3 subset specificity is determined by interactions with other cell transcription factors.

Xenopus laevis Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. findings reveal that, in response to Wnt (show WNT2 ELISA Kits) signalling, Dishevelled (show DVL2 ELISA Kits) inhibits CSL (show SMPX ELISA Kits) transcription factors to regulate Notch (show NOTCH1 ELISA Kits) signalling and cell-fate decisions in vivo

  2. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52 (show C12orf52 ELISA Kits)) as a novel rbpj/CBF-1-interacting protein.

  3. The results suggest that a cell-to-cell interaction via the Notch (show NOTCH1 ELISA Kits)/Su(H) pathway has a significant role in the PGC (show PGC ELISA Kits) migration by regulating cell motility.

  4. This "target protector and rescue assay" demonstrates that the phenotypic defects associated with CUGBP1 inactivation in Xenopus are essentially due to the deregulation of Su(H) mRNA.

Mouse (Murine) Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. RBP-J-mediated Notch (show NOTCH1 ELISA Kits) signalling is critical for basophil-dependent immunoregulation. Deficiency of RBP-J influences the immunoregulatory functions of BA, which include activation of T cells and their differentiation into T helper cell subtypes.

  2. Data, including data from studies using cells from transgenic/knockout mice, suggest that Med1 (show MBD4 ELISA Kits) plays role in enamel formation; Med1 (show MBD4 ELISA Kits) induces Alpl (show ALPL ELISA Kits) via stimulation of Notch1 (show NOTCH1 ELISA Kits) signaling by forming Notch1 (show NOTCH1 ELISA Kits)-RBP-Jk complex on Alpl (show ALPL ELISA Kits) promoter. (Med1 (show MBD4 ELISA Kits) = mediator complex subunit 1 (show MED1 ELISA Kits); Alpl (show ALPL ELISA Kits) = alkaline phosphatase, liver-bone-kidney; Notch1 (show NOTCH1 ELISA Kits) = Notch gene homolog 1 (show NOTCH1 ELISA Kits); RBP-Jk = kappa J region recombining binding protein suppressor of hairless)

  3. study uncovered a regulatory network, where miR (show MLXIP ELISA Kits)-182 functions as an important new node that receives inputs from RBP-J and TNF-alpha (show TNF ELISA Kits) signaling and positively regulates inflammatory osteoclastogenesis; suppression of miR (show MLXIP ELISA Kits)-182 by RBP-J serves as an important mechanism that restrains TNF-alpha (show TNF ELISA Kits) induced osteoclastogenesis

  4. structural and biophysical studies demonstrate that RITA (show C12orf52 ELISA Kits) binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch (show NOTCH1 ELISA Kits), our biochemical and cellular assays suggest that RITA (show C12orf52 ELISA Kits) interacts with additional regions in RBP-J.

  5. Intronic Flk1 (show KDR ELISA Kits) genetic enhancer element directs arterial-specific expression via RBPJ-mediated venous repression.

  6. RBP-J mediated by miR (show MLXIP ELISA Kits)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  7. Rbpj-kappa mediated Notch (show NOTCH1 ELISA Kits) signaling plays a critical role in development of hypothalamic Kisspeptin neurons.

  8. Results reveal an essential role for canonical Notch (show NOTCH1 ELISA Kits)/RBP-J signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of GABAergic signaling

  9. The bone marrow contains a progenitor that expresses renin (show REN ELISA Kits) throughout development and possesses a B-lymphocyte (show AKAP17A ELISA Kits) pedigree. This cell requires RBP-J to differentiate.

  10. functions as a transcriptional repressor on the promoter of the microRNA miR (show MLXIP ELISA Kits)-155

RBPJ Antigen Profile

Antigen Summary

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Alternative names and synonyms associated with RBPJ

  • recombination signal binding protein for immunoglobulin kappa J region (Rbpj) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (RBPJ) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (rbpj) Elisa Kit
  • AI843960 Elisa Kit
  • AOS3 Elisa Kit
  • CBF1 Elisa Kit
  • csl Elisa Kit
  • Igkjrb Elisa Kit
  • IGKJRB1 Elisa Kit
  • Igkrsbp Elisa Kit
  • KBF2 Elisa Kit
  • RBP-J Elisa Kit
  • RBP-J kappa Elisa Kit
  • RBPjk Elisa Kit
  • Rbpsuh Elisa Kit
  • Su(H) Elisa Kit
  • SUH Elisa Kit
  • XSu(H) Elisa Kit
  • xsu(h)1 Elisa Kit

Protein level used designations for RBPJ

recombining binding protein suppressor of hairless , CBF-1 , H-2K binding factor-2 , RBP-J kappa , RBP-JK , immunoglobulin kappa J region recombination signal binding protein 1 , renal carcinoma antigen NY-REN-30 , suppressor of hairless homolog , X-Su(H) , suppressor of hairless protein 1 , suppressor of hairless protein homolog , J kappa-recombination signal-binding protein

GENE ID SPECIES
679028 Rattus norvegicus
3516 Homo sapiens
399453 Xenopus laevis
19664 Mus musculus
767928 Bos taurus
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