Browse our Survivin Proteins (BIRC5)

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Survivin Proteins (BIRC5)
On are 15 Survivin (BIRC5) Proteins from 9 different suppliers available. Additionally we are shipping Survivin Antibodies (450) and Survivin Kits (42) and many more products for this protein. A total of 520 Survivin products are currently listed.
AAC-11, Api4, BIR1, bir5a, birc5, epr-1, LOC398389, SIX, Su1, Su2, Survivin, Survivin1, survivin40, svv1, svv2, TIAP, XBIR1, xsurv, xSurvivin, xSurvivin1, xSurvivin2
list all proteins Gene Name GeneID UniProt
BIRC5 11799 O70201

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Survivin Proteins (BIRC5) by Origin

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Top referenced Survivin Proteins

  1. Human Survivin Protein expressed in Escherichia coli (E. coli) - ABIN667066 : ODriscoll, Linehan, Clynes: Survivin: role in normal cells and in pathological conditions. in Current cancer drug targets 2003 (PubMed)
    Show all 2 references for 667066

More Proteins for Survivin Interaction Partners

Zebrafish Survivin (BIRC5) interaction partners

  1. The present studies aim to examine whether and how cilia function (Pkd1 (show PKD1 Proteins) or Pkd2 (show PKD2 Proteins)) and structure (Tg737 (show IFT88 Proteins)) play a role in cystic kidney and aneurysm through survivin downregulation.

  2. Survivin 1 was identified as a key regulator of neurogenesis, vasculo-angiogenesis, hematopoiesis and cardiogenesis.

Xenopus laevis Survivin (BIRC5) interaction partners

  1. the Aurora B (show AURKB Proteins) chromosome passenger protein complex, including INCENP (show INCENP Proteins) and survivin, is regulated during oocyte maturation in Xenopus laevis

Mouse (Murine) Survivin (BIRC5) interaction partners

  1. The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin.

  2. this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin

  3. Survivin was regulated by TGF-beta (show TGFB1 Proteins) and was found to be highly expressed during mucosal healing following intestinal inflammation

  4. Survivin is a key regulator of gut (show GUSB Proteins) tissue integrity by regulating epithelial homeostasis in the stem cell niche.

  5. TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Proteins) in CPCs to mediate cardioprotection and improve cardiac function.

  6. Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Proteins)) cancer stem cell formation and cancer SCC (show CYP11A1 Proteins) development.

  7. In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Proteins) and ki67 (show MKI67 Proteins).

  8. survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.

  9. Survivin directly participates in PRL (show PRL Proteins)-mediated beta cell proliferation via Akt (show AKT1 Proteins), STAT5 (show STAT5A Proteins)-PIM (show PIM1 Proteins) and ERK (show EPHB2 Proteins) signalling pathways during pregnancy

  10. Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.

Survivin (BIRC5) Protein Profile

Protein Summary

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans, gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene, although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate.

Alternative names and synonyms associated with Survivin (BIRC5)

  • baculoviral IAP repeat-containing 5a (birc5a)
  • survivin (LOC398389)
  • baculoviral IAP repeat-containing 5 (BIRC5)
  • baculoviral IAP repeat-containing 5, gene 1 (birc5.1)
  • baculoviral IAP repeat containing 5 (birc5.2)
  • survivin (AaeL_AAEL012446)
  • survivin (CpipJ_CPIJ001663)
  • survivin (CpipJ_CPIJ002689)
  • survivin (CpipJ_CPIJ006694)
  • baculoviral IAP repeat containing 5 (BIRC5)
  • baculoviral IAP repeat-containing 5 (Birc5)
  • AAC-11 protein
  • Api4 protein
  • BIR1 protein
  • bir5a protein
  • birc5 protein
  • epr-1 protein
  • LOC398389 protein
  • SIX protein
  • Su1 protein
  • Su2 protein
  • Survivin protein
  • Survivin1 protein
  • survivin40 protein
  • svv1 protein
  • svv2 protein
  • TIAP protein
  • XBIR1 protein
  • xsurv protein
  • xSurvivin protein
  • xSurvivin1 protein
  • xSurvivin2 protein

Protein level used designations for Survivin Proteins (BIRC5)

baculoviral IAP repeat-containing protein 5 , survivin 1 , survivin , baculoviral IAP repeat-containing protein 5.1 , Survivin 2 , TGas101d21.1 , baculoviral IAP repeat-containing 5, gene 2 , baculoviral IAP repeat-containing protein 5.2 , baculoviral IAP repeat-containing 5 , apoptosis inhibitor survivin , baculoviral IAP repeat-containing 5 (survivin) , apoptosis inhibitor 4

373110 Danio rerio
398389 Xenopus laevis
403540 Canis lupus familiaris
733532 Xenopus (Silurana) tropicalis
733575 Xenopus (Silurana) tropicalis
5576283 Aedes aegypti
6032633 Culex quinquefasciatus
6033880 Culex quinquefasciatus
6038455 Culex quinquefasciatus
100475314 Ailuropoda melanoleuca
442936 Canis lupus familiaris
493835 Felis catus
374078 Gallus gallus
11799 Mus musculus
100527953 Cavia porcellus
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