You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Nuclear Receptor Subfamily 0, Group B, Member 1 Proteins (NR0B1)

Full name:
Nuclear Receptor Subfamily 0, Group B, Member 1 Proteins (NR0B1)
On www.antibodies-online.com are 11 Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Proteins from 4 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 0, Group B, Member 1 Antibodies (140) and many more products for this protein. A total of 163 Nuclear Receptor Subfamily 0, Group B, Member 1 products are currently listed.
Synonyms:
Ahc, Ahch, AHX, DAX, DAX-1, Dax1, DSS, GTD, HHG, NR0B1, NROB1, SRXY2
list all proteins Gene Name GeneID UniProt
NR0B1 190 P51843
NR0B1 11614 Q61066
NR0B1 58850 P70503

Show all synonyms

Nuclear Receptor Subfamily 0, Group B, Member 1 Proteins (NR0B1) by Origin

Select your origin of interest

More Proteins for Nuclear Receptor Subfamily 0, Group B, Member 1 Interaction Partners

Zebrafish Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) interaction partners

  1. The proximity of the expression of dax1 to 5th branchial arch and numerous known tooth markers led us to hypothesize that dax1 is involved in pharyngeal tooth development in the zebrafish.

Human Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) interaction partners

  1. DAX1 and SF1 (show NR5A1 Proteins) expression positively correlated in pediatric adrenocortical tumors, suggesting that these transcription factors might cooperate in adrenocortical tumorigenesis.

  2. This novel mutation (p. V385L) of DAX-1 is the first to be identified in association with secretory azoospermia, thereby highlighting the important role of DAX-1 in spermatogenesis.

  3. DAX-1 is less specific than Ap2beta (show AP2B1 Proteins), however it is a sensitive marker for translocation positive ARMS and can be helpful in their diagnosis if used in combination with Ap2beta (show AP2B1 Proteins)

  4. DAX1 mutations were associated with X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism.

  5. Case Report: novel mutation in the NR0B1 (DAX1) gene in a large family with two boys affected by congenital adrenal hypoplasia.

  6. DAX-1 protein is necessary to maintain normal spermatogenesis. In humans, male fertility has been studied in few patients carrying DAX-1 mutations. Review.

  7. results suggest a previously unknown DAX-1/beta-Catenin (show CTNNB1 Proteins) molecular network controlling HCC (show FAM126A Proteins) development

  8. Two Taiwanese patients with adrenal hypoplasia congenita were detected to have novel mutations of the DAX1 (NR0B1) gene.

  9. Deletion in exon 2 of NR0B1 is associated with late onset X-linked adrenal hypoplasia congenita with hypogonadotropic hypgonadism.

  10. Data suggest that levels of DAX1/NR0B1 in subcapsular zone of adrenal glands (zona glomerulosa) are not prominently different in subjects with primary aldosteronism, subjects with aldosterone-producing adrenocortical adenomas, or normal subjects.

Mouse (Murine) Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) interaction partners

  1. Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells

  2. Dax1 and Nanog have roles in stabilizing mouse embryonic stem cells and induced pluripotency

  3. Here we review the current knowledge on properties, functions and mechanisms of DAX1 action.

  4. Insulin (show INS Proteins)-mediated induction of DAX-1 in Leydig cells of testis may be a key regulatory step of serum sex hormone level in insulin (show INS Proteins)-resistant states.

  5. Dax1 functions as a negative regulator of Esrrb and Oct3/4 (show POU5F1 Proteins), and these molecules form a regulatory loop for controlling the pluripotency and self-renewal capacity of embryonic stem cells.

  6. Transcriptional differences between mouse embryonic and epiblast stem cells is mediated through a Sox2 (show SOX2 Proteins)/Esrrb heterodimer regulating Nr0b1.

  7. Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD (show FADS1 Proteins)) in mice by inhibiting steroidogenic factor-1 (SF1 (show NR5A1 Proteins)) activation of the testis enhancer of SRY-box-9 (Sox9 (show SOX9 Proteins)).

  8. overexpression of DAX-1 had no effect on the retinoic acid-induced differentiation of P19 cells to either endodermal or neuronal cells

  9. these data reveal that both Dax1(-/Y) mice and patients with X-linked AHC exhibit adrenal failure that is consistent with adrenocortical subcapsular progenitor cell depletion and argue for a significant role of Dax1 in maintenance of these cells.

  10. These data indicate that LRH-1 (show NR5A2 Proteins) and Nanog (show NANOG Proteins) cooperate to regulate Dax1 expression in mouse embryonic stem cells.

Cow (Bovine) Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) interaction partners

  1. Involvement of Ad4BP/SF-1 (show NR5A1 Proteins), DAX-1, and COUP-TFII (show NR2F2 Proteins) transcription factor on steroid production and luteinization in ovarian theca cells.

  2. the decrease of Dax-1 transcription factor and the increase in histone H3 (show HIST3H3 Proteins) acetylation may play important roles in progesterone synthesis in luteinizing granulosa cells.

Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Protein Profile

Protein Summary

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1)

  • nuclear receptor subfamily 0, group B, member 1 (NR0B1)
  • nuclear receptor subfamily 0, group B, member 1 (nr0b1)
  • nuclear receptor subfamily 0, group B, member 1 (LOC100228016)
  • nuclear receptor subfamily 0, group B, member 1 (LOC100358557)
  • nuclear receptor subfamily 0, group B, member 1 (Nr0b1)
  • Ahc protein
  • Ahch protein
  • AHX protein
  • DAX protein
  • DAX-1 protein
  • Dax1 protein
  • DSS protein
  • GTD protein
  • HHG protein
  • NR0B1 protein
  • NROB1 protein
  • SRXY2 protein

Protein level used designations for NR0B1

dax1 , nuclear receptor subfamily 0 group B member 1 , nuclear receptor subfamily 0, group B, member 1 , orphan nuclear receptor DAX-1 , DSS-AHC critical region on the X chromosome, gene 1 , DSS-AHC critical region on the X chromosome protein 1 , nuclear hormone receptor , nuclear receptor DAX-1 , nuclear receptor DAX1 , adrenal hyoplasia protein DAX1 , adrenal hypoplasia congenital , adrenal hypoplasia congenita-like protein , adrenal hypoplasia, congenital homolog , DAX1

GENE ID SPECIES
100446689 Pongo abelii
100001692 Danio rerio
100033899 Equus caballus
100049146 Xenopus laevis
100228016 Taeniopygia guttata
100358557 Oryctolagus cuniculus
190 Homo sapiens
491804 Canis lupus familiaris
395285 Gallus gallus
397680 Sus scrofa
11614 Mus musculus
58850 Rattus norvegicus
281949 Bos taurus
100405594 Callithrix jacchus
574154 Macaca mulatta
450140 Pan troglodytes
Selected quality suppliers for Nuclear Receptor Subfamily 0, Group B, Member 1 Proteins (NR0B1)
Did you look for something else?