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Browse our NR1D1 Proteins (NR1D1)

Full name:
Nuclear Receptor Subfamily 1, Group D, Member 1 Proteins (NR1D1)
On www.antibodies-online.com are 4 Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) Proteins from 2 different suppliers available. Additionally we are shipping NR1D1 Antibodies (77) and NR1D1 Kits (2) and many more products for this protein. A total of 86 NR1D1 products are currently listed.
Synonyms:
A530070C09Rik, ear-1, EAR1, Eip75B, hRev, MGC82865, MGC82881, R75201, REV-ERBAALPHA, THRA1, THRAL
list all proteins Gene Name GeneID UniProt
NR1D1 9572 P20393
NR1D1 217166 Q3UV55
Rat NR1D1 NR1D1 252917 Q63503

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NR1D1 Proteins (NR1D1) by Origin

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Zebrafish Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) interaction partners

  1. Two differentially active alternative promoters control the expression of the zebrafish orphan nuclear receptor (show ESRRA Proteins) gene Rev-erbalpha.

Human Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) interaction partners

  1. Highly quantitative fluorescence anisotropy assays in competition mode revealed that the rev-erbA-alpha specificity for the NCoR (show NCOR1 Proteins) corepressor lies in the first two residues of the beta-strand in Interaction Domain 1 of NCoR (show NCOR1 Proteins).

  2. Data show that ubiquitin E3 ligase Siah2 (show SIAH2 Proteins) depletion delays circadian degradation of nuclear hormone receptor (show NR0B1 Proteins) RevErbalpha (Nr1d1) and lengthens period length.

  3. the role of NR1D1 polymorphisms in the regulation of Nuclear receptor REV-ERBalpha and circadian rhythms regulation

  4. associations between NR1D1, RORA (show RORA Proteins) and RORB (show RORB Proteins) genes and bipolar disorder.(

  5. CRY2 (show CRY2 Proteins) and REV-ERB ALPHA as the clock genes upregulated in obesity during the 24 h period and that REV-ERB ALPHA is an important gene associated with MS.

  6. Our results suggest that the REV-ERB ALPHA rs939347 polymorphism could modulate body fat mass in men. The present work supports the role of REV-ERB ALPHA in the development of obesity as well as a potential target for the treatment of obesity

  7. Using free-energy simulations, the study shows that rev-erbA-alpha-induced DNA deformation preferentially occurs by induced fit rather than by conformational selection, even though the DNA is only slightly distorted in the complex.

  8. Rev-erbalpha is a novel regulator of hepatic stellate cell transdifferentation

  9. apoA-IV (show APOA4 Proteins) inhibits hepatic gluconeogenesis by decreasing Glc-6-Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression through NR1D1.

  10. Rev-erbalpha bestows protection against mycobacterial infection by direct gene repression of IL10 (show IL10 Proteins) and thus provide a novel target in modulating macrophage microbicidal properties.

Mouse (Murine) Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) interaction partners

  1. hepatic phosphatidylcholine (show SGMS2 Proteins) is regulated by the circadian clock through a Bmal1 (show ARNTL Proteins)-Rev-erbalpha-Chkalpha axis

  2. REV-ERBalpha regulates the inflammatory response of macrophages through the suppression of IL-6 (show IL6 Proteins) expression.

  3. direct competition between Rev-erbalpha and ROR TFs provides a universal mechanism for self-sustained control of the molecular clock across all tissues, whereas Rev-erbalpha uses lineage-determining factors to convey a tissue-specific epigenomic rhythm that regulates metabolism tailored to the specific need of that tissue.

  4. The expression of Cav1.2 (show CACNA1C Proteins) mRNA was rhythmic and was regulated by the circadian clock component REV-ERBalpha.

  5. These results suggest an important role of Rev-erbalpha and Fabp7 (show FABP7 Proteins) in adult neurogenesis.

  6. These findings reveal a novel, nonredundant function for Rev-erbalpha that links a core component of the circadian gene-regulatory network to the control of dopaminergic and hippocampus-dependent behaviors.

  7. NR1D1 and NCOR1 (show NCOR1 Proteins) interact to regulate circadian expression of Tshb (show TSHB Proteins) mRNA independent of thyroid hormone (show PTH Proteins).

  8. Modifier genes as therapeutics: the nuclear hormone receptor (show NR0B1 Proteins) Rev Erb alpha (Nr1d1) rescues Nr2e3 (show NR2E3 Proteins) associated retinal disease.

  9. Identify hematopoietic cell Rev-erbalpha as a new modulator of atherogenesis in LDL receptor (show LDLR Proteins) knockout mice.

  10. apoA-IV (show APOA4 Proteins) inhibits hepatic gluconeogenesis by decreasing Glc-6-Pase (show G6PC Proteins) and PEPCK (show PEPCK Proteins) gene expression through NR1D1.

Cow (Bovine) Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1) interaction partners

  1. results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha) plays an inhibitory role in the expression of prostaglandin G/H synthetase(PTGS2 (show PTGS2 Proteins)) in both bovine uterine stromal and epithelial cells treated with ovarian steroids

  2. Rev-ErbAalpha is highly expressed in articular chondrocytes

NR1D1 Protein Profile

Protein Summary

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.

Alternative names and synonyms associated with NR1D1

  • nuclear receptor subfamily 1, group D, member 1 (nr1d1)
  • nuclear receptor subfamily 1, group d, member 1 (nr1d1)
  • nuclear receptor subfamily 1, group D, member 1 (NR1D1)
  • nuclear receptor subfamily 1, group D, member 1 (Nr1d1)
  • A530070C09Rik protein
  • ear-1 protein
  • EAR1 protein
  • Eip75B protein
  • hRev protein
  • MGC82865 protein
  • MGC82881 protein
  • R75201 protein
  • REV-ERBAALPHA protein
  • THRA1 protein
  • THRAL protein

Protein level used designations for NR1D1

nuclear receptor subfamily 1, group D, member 1 , Reverbalpha , ear1 , nuclear receptor subfamily 1 group D member 1 , Rev-ErbAalpha , V-erbA-related protein 1 , nuclear receptor Rev-ErbA-alpha , rev-erbA-alpha , EAR-1 , REV-ERBalpha , Rev-ErbA-alpha protein , nuclear receptor protein , orphan nuclear receptor , rev-erb alpha , rev-erbA alpha , rev-erbA(alpha) , V-erbA-related protein EAR-1 , Rev-erbA-alpha

GENE ID SPECIES
444369 Xenopus laevis
494487 Danio rerio
9572 Homo sapiens
217166 Mus musculus
100688236 Canis lupus familiaris
768225 Bos taurus
252917 Rattus norvegicus
641342 Sus scrofa
100174903 Ovis aries
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