Browse our anti-Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) Antibodies

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anti-Nuclear Receptor Subfamily 1, Group H, Member 2/3 Antibodies (NR1H2/3)
On www.antibodies-online.com are 2 Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) Antibodies from 2 different suppliers available. A total of 2 Nuclear Receptor Subfamily 1, Group H, Member 2/3 products are currently listed.
Synonyms:
LXR-a, LXRA, RLD-1
list all antibodies Gene Name GeneID UniProt
NR1H2/3 10062 Q13133
NR1H2/3    
NR1H2/3    

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Top referenced anti-Nuclear Receptor Subfamily 1, Group H, Member 2/3 Antibodies

  1. Human Polyclonal NR1H2/3 Primary Antibody for ELISA, WB - ABIN250297 : Tangirala, Bischoff, Joseph, Wagner, Walczak, Laffitte, Daige, Thomas, Heyman, Mangelsdorf, Wang, Lusis, Tontonoz, Schulman: Identification of macrophage liver X receptors as inhibitors of atherosclerosis. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
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More Antibodies against Nuclear Receptor Subfamily 1, Group H, Member 2/3 Interaction Partners

Human Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) interaction partners

  1. GW3965 significantly increases the expression of liver X nuclear receptor beta (show NR1H2 Antibodies) (LXRbeta (show NR1H2 Antibodies)) mRNA, while the liver X nuclear receptor alpha (LXRalpha (show NR1H3 Antibodies)( mRNA expression did not change a lot, and sensitizes gefitinib by inhibiting NF-kappa B (NF-kappaB (show NFKB1 Antibodies)) activation.

  2. Transactivation assays showed that MCFA activated LXRa, whereas long-chain FA caused no effect. Our results suggest that LXRa functions as a receptor for saturated FA or acyl-CoA of C10 and C12 in length.

  3. We demonstrated that LXR (show NR1H3 Antibodies) stimulation decreases mRNA and protein expression of FLOT2 (show FLOT2 Antibodies) and DHHC5 (show ZDHHC5 Antibodies) in MCF-7 cells. LXR (show NR1H3 Antibodies) stimulation also reduces Akt (show AKT1 Antibodies) phosphorylation and its localization at the plasma membrane

  4. The effects of LXR (show NR1H3 Antibodies) agonist on interleukin-8 (IL-8 (show IL8 Antibodies)) secretion and nuclear factor-kappa B (NF-kappaB (show NFKB1 Antibodies)) activation in human umbilical vein endothelial cells (HUVECs), is reported.

  5. Collectively, these findings demonstrate that LXRalpha (show NR1H3 Antibodies) activation induces 17beta-HSD13 expression in a SREBP-1c (show SREBF1 Antibodies)-dependent manner.

  6. mutant NR1H3 (LXRA (show NR1H3 Antibodies)) alters gene expression profiles, suggesting a disruption in transcriptional regulation as one of the mechanisms underlying Multiple Sclerosis pathogenesis.

  7. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (show IL1B Antibodies), IL-6 (show IL6 Antibodies) and TNFalpha (show TNF Antibodies) mRNA degradation, destabilized TNFalpha (show TNF Antibodies) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP (show ZFP36 Antibodies)).

  8. RXRalpha (show RXRA Antibodies) negatively regulates the transcription and expression by directly binding to the RARE in the promoter of Cx43 (show GJA1 Antibodies)

  9. Serum and placental LXR-alpha (show NR1H3 Antibodies) and endoglin (show ENG Antibodies) levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).

  10. this study shows that the anti-inflammatory effect of platycodin D in IL-1beta (show IL1B Antibodies)-stimulated chondrocytes is mediated by activating LXR-a

Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 1, Group H, Member 2/3 (NR1H2/3)

  • nuclear receptor subfamily 1, group H, member 3 (NR1H3) antibody
  • LXR-a antibody
  • LXRA antibody
  • RLD-1 antibody

Protein level used designations for NR1H2/3

liver X nuclear receptor alpha variant 1 , oxysterols receptor LXR-alpha

GENE ID SPECIES
10062 Homo sapiens
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