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Browse our anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies

Full name:
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 Antibodies (NR1H3)
On www.antibodies-online.com are 125 Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies from 25 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 1, Group H, Member 3 Kits (18) and Nuclear Receptor Subfamily 1, Group H, Member 3 Proteins (14) and many more products for this protein. A total of 168 Nuclear Receptor Subfamily 1, Group H, Member 3 products are currently listed.
Synonyms:
AU018371, im:7141239, LXR, LXR-a, LXR-alpha, LXRA, LXRalpha, NR1H3, RLD-1, RLD1, Unr1, wu:fd59b01, zgc:113339, zgc:158542
list all antibodies Gene Name GeneID UniProt
NR1H3 10062 Q13133
NR1H3 22259 Q9Z0Y9
NR1H3 58852  

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All available anti-Nuclear Receptor Subfamily 1, Group H, Member 3 Antibodies

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Top referenced anti-Nuclear Receptor Subfamily 1, Group H, Member 3 Antibodies

  1. Human Polyclonal NR1H3 Primary Antibody for GS, ICC - ABIN4331875 : DiBlasio-Smith, Arai, Quinet, Evans, Kornaga, Basso, Chen, Feingold, Halpern, Liu, Nambi, Savio, Wang, Mounts, Isler, Slager, Burczynski, Dorner, LaVallie: Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells. in Journal of translational medicine 2008 (PubMed)
    Show all 4 references for ABIN4331875

  2. Human Polyclonal NR1H3 Primary Antibody for EIA, IHC (p) - ABIN500202 : Bensinger, Tontonoz: Integration of metabolism and inflammation by lipid-activated nuclear receptors. in Nature 2008 (PubMed)
    Show all 4 references for ABIN500202

  3. Human Polyclonal NR1H3 Primary Antibody for EIA, FACS - ABIN953747 : Nedumaran, Kim, Hong, Yoon, Kim, Lee, Lee, Koo, Choi: Orphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN953747

  4. Human Polyclonal NR1H3 Primary Antibody for ELISA, WB - ABIN185294 : Tangirala, Bischoff, Joseph, Wagner, Walczak, Laffitte, Daige, Thomas, Heyman, Mangelsdorf, Wang, Lusis, Tontonoz, Schulman: Identification of macrophage liver X receptors as inhibitors of atherosclerosis. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN185294

  5. Cow (Bovine) Polyclonal NR1H3 Primary Antibody for WB - ABIN2780708 : Albers, Blume, Schlueter, Wright, Kober, Kremoser, Deuschle, Koegl: A novel principle for partial agonism of liver X receptor ligands. Competitive recruitment of activators and repressors. in The Journal of biological chemistry 2006 (PubMed)

  6. Human Polyclonal NR1H3 Primary Antibody for ELISA, ICC - ABIN4331876 : Ahn, Jang, Jun, Lee, Shin: Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease. in Digestive diseases and sciences 2014 (PubMed)

  7. Cow (Bovine) Polyclonal NR1H3 Primary Antibody for WB - ABIN2780709 : Torra, Ismaili, Feig, Xu, Cavasotto, Pancratov, Rogatsky, Neubert, Fisher, Garabedian: Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. in Molecular and cellular biology 2008 (PubMed)

More Antibodies against Nuclear Receptor Subfamily 1, Group H, Member 3 Interaction Partners

Rhesus Monkey Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Liver x receptor modulation of gene expression leads to proluteolytic effects in primate luteal cells. LXR activation causes increased cholesterol efflux and decreased extracellular cholesterol uptake.

Human Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Collectively, these findings demonstrate that LXRalpha activation induces 17beta-HSD13 expression in a SREBP-1c (show SREBF1 Antibodies)-dependent manner.

  2. mutant NR1H3 (LXRA) alters gene expression profiles, suggesting a disruption in transcriptional regulation as one of the mechanisms underlying Multiple Sclerosis pathogenesis.

  3. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (show IL1B Antibodies), IL-6 (show IL6 Antibodies) and TNFalpha (show TNF Antibodies) mRNA degradation, destabilized TNFalpha (show TNF Antibodies) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP (show ZFP36 Antibodies)).

  4. RXRalpha (show RXRA Antibodies) negatively regulates the transcription and expression by directly binding to the RARE in the promoter of Cx43 (show GJA1 Antibodies)

  5. Serum and placental LXR-alpha and endoglin (show ENG Antibodies) levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).

  6. this study shows that the anti-inflammatory effect of platycodin D in IL-1beta (show IL1B Antibodies)-stimulated chondrocytes is mediated by activating LXR-a

  7. results indicated that down-regulation of LXRalpha was shown to suppress invasion and EMT (show ITK Antibodies) of gastric cancer cells

  8. this study shows that show that H2O2 exerts a dual regulation on mRNA expression of LXRalpha and its target genes

  9. combined PPARgamma (show PPARG Antibodies) C1431T, PGC-1alpha (show PPARGC1A Antibodies) G482S, and LXRalpha -115G/A polymorphisms increase the risk of coronary artery disease and predicted the severity of coronary atherosclerosis in Thais

  10. Distinct gene regulatory programs define the inhibitory effects of liver X receptors, NR1H2 (show NR1H2 Antibodies)/NR1H3 and PPARG (show PPARG Antibodies) on cancer cell proliferation.

Mouse (Murine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. EEPD1 is a novel LXR-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1 (show ABCA1 Antibodies).

  2. luteolin can abolish lipid accumulation induced by LXR-SREBP-1c (show SREBF1 Antibodies) activation both in vivo and in vitro

  3. induction of ABCG1 expression by MEK1/2 inhibitors was associated with activation of SIRT1, a positive regulator of LXR activity, and inactivation of SULT2B1 and RIP140, two negative regulators of LXR activity

  4. geranylgeranyl pyrophosphate may act as an endogenous regulator of adipocyte differentiation and maturation through a mechanism partially dependent on the LXR pathway.

  5. these data demonstrate that O3-derived oxysterols have pro-inflammatory functions and form lipid-protein adducts with LXR, thus leading to suppressed cholesterol regulatory gene expression and providing a biochemical mechanism mediating O3-derived formation of oxidized lipids in the airways and subsequent adverse health effects.

  6. Overall, our results suggest that LXR agonist pretreatment could protect against DEX-induced deficits in cerebellar development in postnatal mice and may thus be perspective recruited to counteract such GC side effects.

  7. ABCG1 (show ABCG1 Antibodies) expression was down-regulated by TLR4 (show TLR4 Antibodies), which induces inflammation and lipid accumulation in vascular smooth muscle cells via PPARgamma (show PPARG Antibodies)/LXRalpha signaling.

  8. LXRalpha(-/-) myocardial infarction (MI) murine hearts demonstrated significantly increased infarct size, reduced ejection fraction , aggravated left ventricular (LV) chamber dilation, enhanced fibrosis and reduced angiogenesis. In addition, LXRalpha(-/-) mice had increased mortality compared with Wild-type (WT) mice. LXRalpha deficiency increases mortality, aggravates pathological injury and LV remodeling induced by MI.

  9. this study shows that suggest that activated LXRalpha competes with IRF3 (show IRF3 Antibodies) for GRIP1 (show NCOA2 Antibodies) binding, thus repressing IRF3 (show IRF3 Antibodies) and NF-kappaB (show NFKB1 Antibodies) transcriptional activity and inhibiting the inflammatory response initiated by LPS (show TLR4 Antibodies) in Kupffer cells

  10. HDAC5 inhibits hepatic lipogenic genes expression by attenuating the transcriptional activity of liver X receptor.

Cow (Bovine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. The effects of genetic polymorphisms of liver X receptor, alpha (LXR), stearoyl-CoA desaturase (SCD (show SCD Antibodies)), Fatty acid synthase (FASN (show FASN Antibodies)), and Fatty acid binding protein 4 (FABP4) were investigated on fatty acid composition in fat tissue of steers.

  2. LXRalpha V133I polymorphism had a significant effect on linoleic acid composition in intramuscular fat.

Zebrafish Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Intestinal nr1h3 activation delays transport of absorbed neutral lipids, with accumulation of neutral lipids in enterocyte cytoplasmic droplets.

  2. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

  3. Results describe transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish.

Pig (Porcine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Allele A of the exon5-A201C in NR1H3 promotes a reduction in backfat thicknes.NR1H3 plays role in lipid deposition.

  2. discovery and examination of two polymorphisms in LXRA (LXRA Bsl in exon 2, and LXRA HpyCH4 III in intron 8) and one polymorphism in LXRB (LXRB (show NR1H2 Antibodies) Aci I in exon 5) for genetic linkage and association analyses in fat content or leanness in pigs [LXRA & LRRB]

Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3)

  • nuclear receptor subfamily 1, group H, member 3 (NR1H3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (nr1h3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (Nr1h3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (LOC100352900) antibody
  • AU018371 antibody
  • im:7141239 antibody
  • LXR antibody
  • LXR-a antibody
  • LXR-alpha antibody
  • LXRA antibody
  • LXRalpha antibody
  • NR1H3 antibody
  • RLD-1 antibody
  • RLD1 antibody
  • Unr1 antibody
  • wu:fd59b01 antibody
  • zgc:113339 antibody
  • zgc:158542 antibody

Protein level used designations for NR1H3

nuclear receptor subfamily 1, group H, member 3 , oxysterols receptor LXR-alpha-like , liver X nuclear receptor alpha variant 1 , oxysterols receptor LXR-alpha , LXR alpha , liver X receptor alpha , ubiquitously-expressed nuclear receptor 1 , nuclear orphan receptor LXR-alpha , nuclear receptor subfamily 1 group H member 3 , LXRalpha , liver X receptor , lxr , nuclear oxysterol receptor LxR-alpha , RLD-1

GENE ID SPECIES
466507 Pan troglodytes
713679 Macaca mulatta
100224796 Taeniopygia guttata
100388967 Callithrix jacchus
100453246 Pongo abelii
100567692 Anolis carolinensis
100605954 Nomascus leucogenys
10062 Homo sapiens
22259 Mus musculus
483625 Canis lupus familiaris
507176 Bos taurus
100352900 Oryctolagus cuniculus
548341 Danio rerio
395221 Gallus gallus
397553 Sus scrofa
58852 Rattus norvegicus
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