Browse our anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies

On www.antibodies-online.com are 128 Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies from 25 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 1, Group H, Member 3 Kits (19) and Nuclear Receptor Subfamily 1, Group H, Member 3 Proteins (14) and many more products for this protein. A total of 172 Nuclear Receptor Subfamily 1, Group H, Member 3 products are currently listed.
Synonyms:
AU018371, im:7141239, LXR, LXR-a, LXR-alpha, LXRA, LXRalpha, NR1H3, RLD-1, RLD1, Unr1, wu:fd59b01, zgc:113339, zgc:158542
list all antibodies Gene Name GeneID UniProt
NR1H3 10062 Q13133
NR1H3 22259 Q9Z0Y9
NR1H3 58852  

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More Antibodies against Nuclear Receptor Subfamily 1, Group H, Member 3 Interaction Partners

Rhesus Monkey Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Liver x receptor modulation of gene expression leads to proluteolytic effects in primate luteal cells. LXR activation causes increased cholesterol efflux and decreased extracellular cholesterol uptake.

Human Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. results indicated that LXRalpha plays a specific and important role in activation of TH by regulating D1, and that LXRalpha binds to and regulates the hDIO1 promoter, competing with TRbeta (show TXNRD2 Antibodies) on specific sequences within the promoter.

  2. GW3965 significantly increases the expression of liver X nuclear receptor beta (show NR1H2 Antibodies) (LXRbeta (show NR1H2 Antibodies)) mRNA, while the liver X nuclear receptor alpha (LXRalpha( mRNA expression did not change a lot, and sensitizes gefitinib by inhibiting NF-kappa B (NF-kappaB (show NFKB1 Antibodies)) activation.

  3. Transactivation assays showed that MCFA activated LXRa, whereas long-chain FA caused no effect. Our results suggest that LXRa functions as a receptor for saturated FA or acyl-CoA of C10 and C12 in length.

  4. We demonstrated that LXR stimulation decreases mRNA and protein expression of FLOT2 (show FLOT2 Antibodies) and DHHC5 (show ZDHHC5 Antibodies) in MCF-7 cells. LXR stimulation also reduces Akt (show AKT1 Antibodies) phosphorylation and its localization at the plasma membrane

  5. The effects of LXR agonist on interleukin-8 (IL-8 (show IL8 Antibodies)) secretion and nuclear factor-kappa B (NF-kappaB (show NFKB1 Antibodies)) activation in human umbilical vein endothelial cells (HUVECs), is reported.

  6. Collectively, these findings demonstrate that LXRalpha activation induces 17beta-HSD13 expression in a SREBP-1c (show SREBF1 Antibodies)-dependent manner.

  7. mutant NR1H3 (LXRA) alters gene expression profiles, suggesting a disruption in transcriptional regulation as one of the mechanisms underlying Multiple Sclerosis pathogenesis.

  8. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (show IL1B Antibodies), IL-6 (show IL6 Antibodies) and TNFalpha (show TNF Antibodies) mRNA degradation, destabilized TNFalpha (show TNF Antibodies) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP (show ZFP36 Antibodies)).

  9. RXRalpha (show RXRA Antibodies) negatively regulates the transcription and expression by directly binding to the RARE in the promoter of Cx43 (show GJA1 Antibodies)

  10. Serum and placental LXR-alpha and endoglin (show ENG Antibodies) levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).

Mouse (Murine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. treatment of APP/E4/Abca1+/- mice with liver X receptor (LXR) agonist T0 ameliorates APOE4-induced Alzheimer's disease (AD)-like pathology and therefore targeting the LXR-ABCA1-APOE regulatory axis could be effective as a potential therapeutic approach in AD patients, carriers of APOEepsilon4

  2. Our data indicate that a combination of vildagliptin and pravastatin significantly induces the expression of LXR-ABCA1 (show ABCA1 Antibodies)/ABCG1 (show ABCG1 Antibodies) cascade and improves cholesterol efflux (P > 0.05) in adipocytes. Our data may explain, at least in part, the improvement in HDL (show HSD11B1 Antibodies)-C levels observed in patients receiving both medications

  3. We describe a molecular pathway comprising miR-155 and its epigenetic LXRalpha target that when deregulated enables pathogenic pulmonary fibrosis. Manipulation of the miR-155/LXR pathway may have therapeutic potential for idiopathic pulmonary fibrosis.

  4. 27OH is not an important regulator of Srebp- or LXR regulated genes under basal conditions in mouse liver

  5. within the CNS, each LXR isoform differentially influences myelin gene mRNA levels in a region- and age-dependant manner, participating in the fine regulation of myelin gene expression

  6. EEPD1 is a novel LXR-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1 (show ABCA1 Antibodies).

  7. luteolin can abolish lipid accumulation induced by LXR-SREBP-1c (show SREBF1 Antibodies) activation both in vivo and in vitro

  8. induction of ABCG1 expression by MEK1/2 inhibitors was associated with activation of SIRT1, a positive regulator of LXR activity, and inactivation of SULT2B1 and RIP140, two negative regulators of LXR activity

  9. geranylgeranyl pyrophosphate may act as an endogenous regulator of adipocyte differentiation and maturation through a mechanism partially dependent on the LXR pathway.

  10. these data demonstrate that O3-derived oxysterols have pro-inflammatory functions and form lipid-protein adducts with LXR, thus leading to suppressed cholesterol regulatory gene expression and providing a biochemical mechanism mediating O3-derived formation of oxidized lipids in the airways and subsequent adverse health effects.

Cow (Bovine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. The effects of genetic polymorphisms of liver X receptor, alpha (LXR), stearoyl-CoA desaturase (SCD (show SCD Antibodies)), Fatty acid synthase (FASN (show FASN Antibodies)), and Fatty acid binding protein 4 (FABP4) were investigated on fatty acid composition in fat tissue of steers.

  2. LXRalpha V133I polymorphism had a significant effect on linoleic acid composition in intramuscular fat.

Zebrafish Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Intestinal nr1h3 activation delays transport of absorbed neutral lipids, with accumulation of neutral lipids in enterocyte cytoplasmic droplets.

  2. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

  3. Results describe transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish.

Pig (Porcine) Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) interaction partners

  1. Allele A of the exon5-A201C in NR1H3 promotes a reduction in backfat thicknes.NR1H3 plays role in lipid deposition.

  2. discovery and examination of two polymorphisms in LXRA (LXRA Bsl in exon 2, and LXRA HpyCH4 III in intron 8) and one polymorphism in LXRB (LXRB (show NR1H2 Antibodies) Aci I in exon 5) for genetic linkage and association analyses in fat content or leanness in pigs [LXRA & LRRB]

Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3)

  • nuclear receptor subfamily 1, group H, member 3 (NR1H3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (nr1h3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (Nr1h3) antibody
  • nuclear receptor subfamily 1, group H, member 3 (LOC100352900) antibody
  • AU018371 antibody
  • im:7141239 antibody
  • LXR antibody
  • LXR-a antibody
  • LXR-alpha antibody
  • LXRA antibody
  • LXRalpha antibody
  • NR1H3 antibody
  • RLD-1 antibody
  • RLD1 antibody
  • Unr1 antibody
  • wu:fd59b01 antibody
  • zgc:113339 antibody
  • zgc:158542 antibody

Protein level used designations for NR1H3

nuclear receptor subfamily 1, group H, member 3 , oxysterols receptor LXR-alpha-like , liver X nuclear receptor alpha variant 1 , oxysterols receptor LXR-alpha , LXR alpha , liver X receptor alpha , ubiquitously-expressed nuclear receptor 1 , nuclear orphan receptor LXR-alpha , nuclear receptor subfamily 1 group H member 3 , LXRalpha , liver X receptor , lxr , nuclear oxysterol receptor LxR-alpha , RLD-1

GENE ID SPECIES
466507 Pan troglodytes
713679 Macaca mulatta
100224796 Taeniopygia guttata
100388967 Callithrix jacchus
100453246 Pongo abelii
100567692 Anolis carolinensis
100605954 Nomascus leucogenys
10062 Homo sapiens
22259 Mus musculus
483625 Canis lupus familiaris
507176 Bos taurus
100352900 Oryctolagus cuniculus
548341 Danio rerio
395221 Gallus gallus
397553 Sus scrofa
58852 Rattus norvegicus
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