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Browse our Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2)

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Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2)
On www.antibodies-online.com are 8 Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) Proteins from 6 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 2, Group C, Member 2 Antibodies (206) and Nuclear Receptor Subfamily 2, Group C, Member 2 Kits (3) and many more products for this protein. A total of 235 Nuclear Receptor Subfamily 2, Group C, Member 2 products are currently listed.
Synonyms:
B430101B05, C87327, gb:dq017625, hTAK1, im:6911408, mKIAA4145, TAK1, TR2R1, Tr4
list all proteins Gene Name GeneID UniProt
NR2C2 313121 P0C8E4
NR2C2 26409 Q62073
NR2C2 7182 P49116

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Nuclear Receptor Subfamily 2, Group C, Member 2 Proteins (NR2C2) by Origin

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More Proteins for Nuclear Receptor Subfamily 2, Group C, Member 2 Interaction Partners

Mouse (Murine) Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) interaction partners

  1. Data show that TGFbeta (show TGFB1 Proteins)-activated kinase-1 (TAK1) activated nuclear factor of activated T-cells (NFAT (show NFATC1 Proteins))/NF-kappa B (NFkappaB (show NFKB1 Proteins)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (show BNIP3 Proteins)), and inhibited cardiac cell death.

  2. Crucial functions of inflammatory TAK1-NEMO (show IKBKG Proteins) signaling in protecting the brain endothelium and maintaining normal brain function.

  3. Roles of TAK1 in vascular oxidative stress and its contribution to neointima formation after vascular injury.

  4. Inactivation of TAK1 in satellite cells inhibits muscle regeneration in adult mice.

  5. our current study highlighted the emerging role of TAK1 in configuring the gut (show GUSB Proteins)-specialized T cell subset, which regulates mucosal homeostasis under lymphopenic conditions.

  6. the ADAP (show APP Proteins) CARMA1 (show CARD11 Proteins) binding site is required for IKK gamma (show IKBKG Proteins) ubiquitination; both TAK1 and CARMA1 (show CARD11 Proteins) binding sites are required for IkappaB alpha (show NFKBIA Proteins) phosphorylation and degradation and NF-kappaB (show NFKB1 Proteins) nuclear translocation

  7. Results provide evidence that TAK1 is required for the activation of NF-kappaB (show NFKB1 Proteins) in thymocytes and suggest that TAK1 plays a central role in both innate and adaptive immunity.

  8. TAK1 is essential for connective tissue deposition in the dermis.

  9. Tak1 functions to regulate tongue development by controlling Fgf10 expression and could represent a candidate gene for mutation in human PRS clefting.

  10. In vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammation.

Human Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) interaction partners

  1. miR (show MLXIP Proteins)-203 represses NF-kappaB (show NFKB1 Proteins) signaling via targeting TAK1 (show MAP3K7 Proteins) and PI3KCA and miR (show MLXIP Proteins)-203 overexpression may contribute to the COPD (show ARCN1 Proteins) initiation.

  2. DK1 inhibits the formation of the TAK1 (show MAP3K7 Proteins)-TAB2 (show TAB2 Proteins)-TRAF6 (show TRAF6 Proteins) complex and leads to the inhibition of TRAF6 (show TRAF6 Proteins) ubiquitination.

  3. IFIT5 promotes SeV-induced IKK (show CHUK Proteins) phosphorylation and NF-kappaB (show NFKB1 Proteins) activation by regulating the recruitment of IKK (show CHUK Proteins) to TAK1 (show MAP3K7 Proteins).

  4. USP18 (show USP18 Proteins) negatively regulates NF-kappaB (show NFKB1 Proteins) signaling by targeting TAK1 (show MAP3K7 Proteins) and NEMO (show IKBKG Proteins) for deubiquitination through distinct mechanisms.

  5. Helicobacter pylori induces internalization of EGFR (show EGFR Proteins) via novel TAK1 (show MAP3K7 Proteins)-p38 (show CRK Proteins)-serine activation pathway which is independent of HB-EGF (show HBEGF Proteins).

  6. Together, these results demonstrate that LYTAK1 inhibits LPS (show IRF6 Proteins)-induced production of several pro-inflammatory cytokines and endotoxin shock probably through blocking TAK1 (show MAP3K7 Proteins)-regulated signalings.

  7. TR4 expression in NSCLC samples is significantly associated with poor clinicopathological features, and TR4 plays an important role in the metastatic capacity of NSCLC cells by EMT (show ITK Proteins) regulation.

  8. TR4 may increase prostate cancer metastasis and invasion via decreasing the miR (show MLXIP Proteins)-373-3p expression that resulted in the activation of the TGFbetaR2/p-Smad3 (show SMAD3 Proteins) signals.

  9. TR4 was found to mediate the prostate cancer cells' radio-sensitivity.

  10. Results suggest that the testicular nuclear receptor 4 (TR4) and oncogene (show RAB1A Proteins) EZH2 (show EZH2 Proteins) signaling may play a critical role in the prostate cancer stem/progenitor cell invasion.

Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) Protein Profile

Protein Summary

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996

Alternative names and synonyms associated with Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2)

  • mitogen activated protein kinase kinase kinase 7 (Map3k7)
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7)
  • nuclear receptor subfamily 2, group C, member 2 (NR2C2)
  • nuclear receptor subfamily 2, group C, member 2 (Nr2c2)
  • nuclear receptor subfamily 2, group C, member 2 (nr2c2)
  • B430101B05 protein
  • C87327 protein
  • gb:dq017625 protein
  • hTAK1 protein
  • im:6911408 protein
  • mKIAA4145 protein
  • TAK1 protein
  • TR2R1 protein
  • Tr4 protein

Protein level used designations for NR2C2

TGF-beta activated kinase 1 , mitogen-activated protein kinase kinase kinase 7 , TGF-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , Nuclear hormone receptor TR4 , TR4 nuclear hormone receptor , nuclear receptor subfamily 2 group C member 2 , orphan nuclear receptor TAK1 , orphan nuclear receptor TR4 , testicular nuclear receptor 4 , testicular receptor 4 , nuclear receptor subfamily 2, group H, member 2 , orphan receptor, TR4 , TR4 orphan receptor , TR4-NS orphan receptor , orphan receptor TR4

GENE ID SPECIES
313121 Rattus norvegicus
26409 Mus musculus
7182 Homo sapiens
484641 Canis lupus familiaris
505531 Bos taurus
22026 Mus musculus
50659 Rattus norvegicus
569321 Danio rerio
395253 Gallus gallus
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