Browse our anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibodies

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anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibodies (NR3C1)
On www.antibodies-online.com are 294 Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antibodies from 27 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Kits (73) and Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Proteins (17) and many more products for this protein. A total of 392 Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) products are currently listed.
Synonyms:
GCCR, GCL, GCR, gr, GR-A, GRL, Grl-1, Grl1, LOC100302444, NO, nr3c1, xGR, zgc:113038
list all antibodies Gene Name GeneID UniProt
NR3C1 24413 P06536
NR3C1 14815  
NR3C1 2908 P04150

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All available anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibodies

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Top referenced anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibodies

  1. Human Monoclonal NR3C1 Primary Antibody for BI, IF - ABIN968430 : Beato, Herrlich, Schütz: Steroid hormone receptors: many actors in search of a plot. in Cell 1996 (PubMed)
    Show all 3 references for 968430

  2. Human Polyclonal NR3C1 Primary Antibody for IHC (fro), IHC (p) - ABIN1107374 : Encío, Detera-Wadleigh: The genomic structure of the human glucocorticoid receptor. in The Journal of biological chemistry 1991 (PubMed)
    Show all 3 references for 1107374

  3. Human Polyclonal NR3C1 Primary Antibody for IF, IHC (p) - ABIN651060 : Geelhoed, Steegers, Koper, van Rossum, Moll, Raat, Tiemeier, Hofman, Jaddoe: Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study. in BMC medical genetics 2010 (PubMed)
    Show all 2 references for 651060

  4. Human Polyclonal NR3C1 Primary Antibody for WB - ABIN1881586 : Seitz, Thoma, Schoch, Stihle, Benz, DArcy, Wiget, Ruf, Hennig, Sterner: Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. in Journal of molecular biology 2010 (PubMed)

  5. Human Polyclonal NR3C1 Primary Antibody for FACS, IF (p) - ABIN726875 : Takigawa, Miyazaki, Kinoshita, Kawarabayashi, Nishiyama, Hatsuse, Ono, Saitoh, Seki, Yamamoto: Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice. in American journal of physiology. Gastrointestinal and liver physiology 2013 (PubMed)

  6. Human Polyclonal NR3C1 Primary Antibody for ChIP, ICC - ABIN152786 : Liang, Kowalczyk, Junco, Klug-De Santiago, Malik, Wei, Slaga: Differential effects on lung cancer cell proliferation by agonists of glucocorticoid and PPARα receptors. in Molecular carcinogenesis 2014 (PubMed)

  7. Human Monoclonal NR3C1 Primary Antibody for EIA, IHC (fro) - ABIN118958 : Berki, Kumánovics, Kumánovics, Falus, Ujhelyi, Németh: Production and flow cytometric application of a monoclonal anti-glucocorticoid receptor antibody. in Journal of immunological methods 1998 (PubMed)

  8. Human Polyclonal NR3C1 Primary Antibody for WB - ABIN2792573 : : Triazolam Effects On Explicit Memory, Implicit Memory and Metamemory: Lister RG, Joyce EM, Weingartner HJ, Eckardt MJ Laboratory of Clinical Studies, NIAAA, DICBR, Bldg 10 Rm 3C102, 9000 Rockville Pike, Bethesda, MD 20892, USA. in Journal of psychopharmacology (Oxford, England) 2012 (PubMed)

  9. Human Polyclonal NR3C1 Primary Antibody for IF, IHC (p) - ABIN651659 : Bosker, Hartman, Nolte, Prins, Terpstra, Posthuma, van Veen, Willemsen, DeRijk, de Geus, Hoogendijk, Sullivan, Penninx, Boomsma, Snieder, Nolen: Poor replication of candidate genes for major depressive disorder using genome-wide association data. in Molecular psychiatry 2011 (PubMed)

  10. Cow (Bovine) Polyclonal NR3C1 Primary Antibody for IHC, WB - ABIN2782262 : Yoshikawa, Shimizu, Sano, Ohnuma, Iwata, Hosono, Fukuda, Morimoto, Tanaka: Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Interaction Partners

Zebrafish Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

Mouse (Murine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. REV-ERBalpha (show NR1D1 Antibodies) binds to the C-terminal portion and GR to the N-terminal portion of HSP90alpha (show HSP90AA2 Antibodies) and HSP90beta (show HSP90AB1 Antibodies), a chaperone responsible for the activation of proteins to ensure survival of a cell.

  2. Phospho-AMPK (show PRKAA1 Antibodies) is a molecular switch able to cooperate with glucocorticoid receptors and Ppar-alpha (show PPARA Antibodies) at the chromatin level, a novel adaptation mechanism to prolonged fasting.

  3. GR signaling decreases NRF2 (show NFE2L2 Antibodies) transcriptional activation through reducing the NRF2 (show NFE2L2 Antibodies)-dependent histone acetylation. Consistent with these observations, GR signaling blocked NRF2 (show NFE2L2 Antibodies)-mediated cytoprotection from oxidative stress.

  4. GRbeta antagonizes the GC-induced signaling during fasting via GRalpha and the PPARalpha (show PPARA Antibodies)-FGF21 (show FGF21 Antibodies) axis that reduces fat burning. Furthermore, hepatic GRbeta increases inflammation, which leads to hepatic lipid accumulation.

  5. liver-specific deletion of GR resulted in a significant increase in mRNA expression of key genes involved in gluconeogenesis and glycogen (show GYS1 Antibodies) metabolism in kidney tissue, indicating a compensatory mechanism to maintain glucose homeostasis. Liver GRKO mice demonstrated decreased fat mass and liver glycogen (show GYS1 Antibodies) content compared with WT mice administered dexamethasone for 2 weeks.

  6. These results established a novel role for GR and KLF13 (show KLF13 Antibodies) signaling in adult cardiomyocytes with potential clinical implications for the prevention of cardiotoxicity induced heart failure.

  7. miR (show MLXIP Antibodies)-433 helps maintain circadian rhythm in osteoblasts by regulating sensitivity to glucocorticoid receptor signaling.

  8. this study shows that Nr3c1 regulates the formation of memory-precursor CD8 (show CD8A Antibodies)+ T cell fates

  9. Chronic subordinate colony housing (chronic psychosocial stressed) mice showed decreased GR mRNA and cytoplasmic protein (show BLZF1 Antibodies) levels compared with single-housed control mice.

  10. Data show that agouti-related protein (AgRP (show AGRP Antibodies))-glucocorticoid receptor knockout (GR-/-) mice are resistant to diet-induced obesity.

Guinea Pig Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. The guinea pig GR-specific mutations within the H1-H3 loop confer global changes within the GR-Hsp90 (show HSP90 Antibodies) complex that favor FKBP51 (show FKBP5 Antibodies) repression over FKBP52 (show FKBP4 Antibodies) potentiation.

Human Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. NR3C1 is a bona fide target of miR (show MLXIP Antibodies)-124 in acute lymphoblastic leukemia.

  2. Numerous direct transcriptional targets of GR exist in airway smooth muscle. Genes with inducible GR occupancy included IRS2 (show IRS2 Antibodies), APPL2 (show APLP2 Antibodies), RAMP1 (show RAMP1 Antibodies), and MFGE8 (show MFGE8 Antibodies). GR occupancy occurred in the absence of supplemental ligand, including robust GR binding peaks within the IL11 (show IL11 Antibodies) and LIF (show LIF Antibodies) loci.

  3. These results demonstrate that BCLI, N363S and ER22/23EK polymorphisms of NR3C1 do not play a pathogenetic role for Adrenal Incidentalomas.

  4. NR3C1 is a haploinsufficient tumor suppressor in a subset of blastic plasmacytoid dendritic cell neoplasms (BPDCN).

  5. Glucocorticoid receptor polymorphisms are associated with altered glucocorticoid sensitivity and changes in glucose homeostasis, and other metabolic parameters (Review)

  6. TR4 (show NR2C2 Antibodies) binds GR to play an important role in glucocorticoid-directed corticotroph tumor POMC (show POMC Antibodies) regulation in addition to modulating glucocorticoid actions on other GR targets.

  7. individuals carrying the ADHD risk haplotype 9beta of NR3C1 showed significantly more positive relation between stress exposure and ADHD severity than non-carriers.

  8. The structure and conformational dynamics of glucocorticoid receptor in complex with small heterodimer partner (show NR0B2 Antibodies) is described.

  9. our studies suggest that the joint influence of positive and negative sequence signals partition the genome into regions where glucocorticoid receptor can bind and those where it cannot.

  10. Hic-5 (show TGFB1I1 Antibodies) regulates GR binding site selection by a novel mechanism, exploiting gene-specific requirements for chromatin remodeling enzymes to selectively influence DNA occupancy and gene regulation by a transcription factor.

Pig (Porcine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. These results indicate that myostatin (show MSTN Antibodies) mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 (show FOXO3 Antibodies) and glucocorticoid receptor binding to its promoter.

  2. Data indicate that higher hepatic glucocorticoid receptor (GR) expression in EHL piglets attributes mainly to the enhanced transcription of GR promoter 1-9/10 from breed-specific interaction of p53 (show TP53 Antibodies) and specificity protein 1 (Sp1 (show SP1 Antibodies)).

  3. Tissue specificities, gene expression and induction responsiveness of the porcine NR3C1 gene.

  4. Cloning and dna sequence analysis of the upstream flanking region of the NR3C1 gene in the domestic pig.

  5. Effects of age, weaning and/or social isolation on the expression of genes regulating glucocorticoid response [glucocorticoid receptor).

Cow (Bovine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. Glucocorticoid Receptor protein expression in granulosa cells was higher in cysts from animals with spontaneous cystic ovarian disease and adrenocorticotropic hormone-induced cystic ovarian disease than in tertiary follicles from control animals.

  2. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2 (show DAB2 Antibodies), and NR3C1. TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.

  3. Bayesian image analysis of dexamethasone and shear stress-induced glucocorticoid receptor intracellular movement

  4. investigation of gene expression for GR, 11HSD1, and 11HSD2 (show HSD11B2 Antibodies) in granulosa cells and theca interna layers during follicular maturation and atresia: expression of GR was largely unchanged during follicular maturation

Rainbow Trout (Oncorhynchus mykiss) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. The E domain of the trout receptors are not involved in the nucleocytoplasmic localization of naive trout GRs (show GARS Antibodies), but the A/B domain, especially if linked to the corresponding trout CD region, plays a pivotal role in the cellular distribution pattern.

Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antigen Profile

Antigen Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).

Alternative names and synonyms associated with Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1)

  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1) antibody
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (nr3c1) antibody
  • nuclear receptor subfamily 3, group C, member 1 (NR3C1) antibody
  • glucocorticoid receptor (LOC100302444) antibody
  • nuclear receptor subfamily 3, group C, member 1 (Nr3c1) antibody
  • GCCR antibody
  • GCL antibody
  • GCR antibody
  • gr antibody
  • GR-A antibody
  • GRL antibody
  • Grl-1 antibody
  • Grl1 antibody
  • LOC100302444 antibody
  • NO antibody
  • nr3c1 antibody
  • xGR antibody
  • zgc:113038 antibody

Protein level used designations for NR3C1

glucocorticoid receptor , nuclear receptor subfamily 3, group C, member 1 , glucocorticoid receptor 1 , GR , nuclear receptor subfamily 3 group C member 1 , glucocorticoid nuclear receptor variant 1 , glucocorticoid receptor alpha , glucocorticoid receptor variant P , glucocorticoid receptor variant beta , glucocorticoid receptor variant gamma

GENE ID SPECIES
100061217 Equus caballus
549721 Xenopus (Silurana) tropicalis
553740 Danio rerio
692348 Felis catus
100302444 Oryzias latipes
24413 Rattus norvegicus
14815 Mus musculus
100135583 Cavia porcellus
2908 Homo sapiens
100008890 Oryctolagus cuniculus
443412 Ovis aries
396740 Sus scrofa
281946 Bos taurus
478047 Canis lupus familiaris
416343 Gallus gallus
100136786 Oncorhynchus mykiss
100173284 Pongo abelii
100394916 Callithrix jacchus
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