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Browse our NR4A2 (NR4A2) ELISA Kits

Full name:
Nuclear Receptor Subfamily 4, Group A, Member 2 ELISA Kits (NR4A2)
On www.antibodies-online.com are 8 Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) ELISA Kits from 4 different suppliers available. Additionally we are shipping NR4A2 Antibodies (68) and NR4A2 Proteins (6) and many more products for this protein. A total of 90 NR4A2 products are currently listed.
Synonyms:
HZF-3, ngf1b, NGFI-B, NOT, nr4a2, nr41/42/43, Nurr1, RNR-1, RNR1, TINOR, TINUR, zgc:92696
list all ELISA KIts Gene Name GeneID UniProt
NR4A2 4929 P43354
NR4A2 54278 Q07917
NR4A2 18227 Q06219

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Top referenced NR4A2 ELISA Kits

  1. Human NR4A2 ELISA Kit for Sandwich ELISA - ABIN819096 : Merino-Zamorano, Hernández-Guillamon, Jullienne, Béhot, Bardou, Parés, Fernández-Cadenas, Giralt, Carrera, Ribó, Vivien, Ali, Rosell, Montaner: NURR1 Involvement in Recombinant Tissue-Type Plasminogen Activator Treatment Complications After Ischemic Stroke. in Stroke; a journal of cerebral circulation 2014 (PubMed)

More ELISA Kits for NR4A2 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) interaction partners

  1. show that unsaturated fatty acids also interact with the Nurr1 LBD, and solution NMR spectroscopy reveals the binding epitope of DHA at its putative ligand-binding pocket

  2. NURR1 is an essential transcription factor for the differentiation, maturation, and maintenance of midbrain dopaminergic neurons.

  3. Nurr1 overexpression exerts neuroprotective and anti-inflammatory roles via down-regulating CCL2 (show CCL2 ELISA Kits) in both in vivo and in vitro Parkinson's disease models, contributing to developing mechanism-based and neuroprotective strategies against PD

  4. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2)early growth response (EGR)2 (show EGR2 ELISA Kits) and NR4A2EGR3. Therefore, RUNX1 (show RUNX1 ELISA Kits), NR4A2, EGR2 (show EGR2 ELISA Kits), EGR3 (show EGR3 ELISA Kits) and ID4 (show ID4 ELISA Kits) may be key genes associated with the pathogenesis of DS.

  5. Our results suggest that NLK (show NLK ELISA Kits) inhibits transcriptional activation of Nurr1 gene by impeding CBP's role as a co-activator of NF-kappaB (show NFKB1 ELISA Kits) and CREB (show CREB1 ELISA Kits) in prostate cancer.

  6. decreased expression levels of Nurr1 were associated with chronic inflammation and insulin (show INS ELISA Kits) resistance in patients with T2D.

  7. The immunohistochemical, qRT-PCR and western blot analyses revealed that Nurr1 expression was increased in gastric cancer tissues compared with normal gastric tissue.

  8. NR4A2 is a key factor in multiple diseases, such as inflammation, cancer and cardiovascular diseases.

  9. A2M (show A2M ELISA Kits) is expressed in the vasculature and NR4A receptors modulate VSMC MMP2 (show MMP2 ELISA Kits)/9 activity by several mechanisms including the up-regulation of A2M (show A2M ELISA Kits).

  10. In this review, a concise overview of the current understanding of the important metabolic roles governed by NR4A members NR4A1 (show NR4A1 ELISA Kits), NR4A2 and NR4A3 (show NR4A3 ELISA Kits) including their participation in a number of diseases shall be provided

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) interaction partners

  1. Overexpression of Nurr1 and Pitx3 (show PITX3 ELISA Kits) in iPSCs could efficiently program induced pluripotent stem cells into functional dopaminergic-like neurons. This finding may have an impact on future stem cell therapy of Parkinson's disease.

  2. Overexpression and knockdown of Nr4a2 demonstrated that Nr4a2 orchestrates the expression of immunoregulatory genes, hence inducing a tolerogenic phenotype in bone marrow derived dendritic cells (DC) in mice. The findings suggest a previously unidentified role for Nr4a2 as a regulator of dendritic cell tolerogenicity and demonstrate its potential as therapeutic target in DC-associated pathophysiologies.

  3. Nurr1 defect induces early experimental autoimmune encephalomyelitis (EAE) onset and increases inflammatory infiltrates in spinal cord suggesting a Nurr1 role in the early phase of EAE

  4. Nr4a2 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.

  5. Results indicate that Nurr1 overexpression in olfactory bulb stem cells induces the formation of two populations of mature dopaminergic neurons with features of the ventral mesencephalon or of the olfactory bulb

  6. Nurr1 +/- genotype predisposes mice to T. gondii-induced alterations in behaviors that involve dopamine neurotransmission

  7. The authors show herein that Nurr1 and Foxa2 (show FOXA2 ELISA Kits) interact to protect midbrain dopaminergic neurons against various toxic insults, but their expression is lost during aging and degenerative processes.

  8. Because the phosphorylation site mutants of NR4A2 cannot rescue the cell death-promoting activity, ASK1 (show MAP3K5 ELISA Kits)-p38 (show CRK ELISA Kits) pathway-dependent phosphorylation and subsequent cytoplasmic translocation of NR4A2 may be required for oxidative stress-induced (show SQSTM1 ELISA Kits) cell death.

  9. Nurr1 protein is prominently expressed in brain areas with Abeta (show APP ELISA Kits) accumulation, that is, the subiculum and the frontal cortex, in the 5XFAD mouse and that Nurr1 is highly co-expressed with Abeta (show APP ELISA Kits) at early stages.

  10. This study showed that nurr1 has a similar mRNA expression pattern and low levels of expression at rest.

Zebrafish Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) interaction partners

  1. data indicate a conserved evolutionary role of Nr4a2 proteins in specification of the neurotransmitter phenotype

  2. Results shed new light on NR4A2 function in the dopamine differentiation pathway, and stress the effect of dopamine dysregulation on the control of locomotor activity.

NR4A2 Antigen Profile

Antigen Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Alternative names and synonyms associated with NR4A2

  • nuclear receptor subfamily 4, group A, member 2 (NR4A2) Elisa Kit
  • nuclear receptor (nr41/42/43) Elisa Kit
  • nuclear receptor related 1 (nurr1) Elisa Kit
  • nuclear receptor subfamily 4, group A, member 2 (nr4a2) Elisa Kit
  • nuclear receptor subfamily 4, group A, member 2 (Nr4a2) Elisa Kit
  • nuclear receptor subfamily 4, group A, member 2b (nr4a2b) Elisa Kit
  • HZF-3 Elisa Kit
  • ngf1b Elisa Kit
  • NGFI-B Elisa Kit
  • NOT Elisa Kit
  • nr4a2 Elisa Kit
  • nr41/42/43 Elisa Kit
  • Nurr1 Elisa Kit
  • RNR-1 Elisa Kit
  • RNR1 Elisa Kit
  • TINOR Elisa Kit
  • TINUR Elisa Kit
  • zgc:92696 Elisa Kit

Protein level used designations for NR4A2

nuclear receptor subfamily 4, group A, member 2 , nuclear receptor , nuclear receptor related 1 , nuclear receptor subfamily 4 group A member 2 , Nuclear receptor subfamily 4 group A member 2 , NGFI-B/nur77 beta-type transcription factor homolog , T-cell nuclear receptor NOT , immediate-early response protein NOT , intermediate-early receptor protein , nur related protein-1, human homolog of , orphan nuclear receptor NR4A2 , orphan nuclear receptor NURR1 , transcriptionally inducible nuclear receptor related 1 , transcriptionally-inducible nuclear receptor , NUR-related factor 1 , RNR-1 , SL-322 , nuclear orphan receptor HZF-3 , nuclear receptor subfamily 4 group A member 2 variant TINUR , nuclear receptor subfamily 4 group A member 2 variant NURR1a , nuclear receptor subfamily 4 group A member 2 variant NURR1b , nuclear receptor subfamily 4 group A member 2 variant NURR1c , nuclear receptor subfamily 4 group A member 2 variant NURR2c , nur related protein 1 , regenerating liver nuclear receptor 1 , nerve growth factor 1b , neural orphan nuclear receptor

GENE ID SPECIES
459669 Pan troglodytes
697077 Macaca mulatta
778703 Ciona intestinalis
100049370 Oryzias latipes
100050666 Equus caballus
100101682 Xenopus (Silurana) tropicalis
100190832 Pongo abelii
100409975 Callithrix jacchus
100482377 Ailuropoda melanoleuca
100589731 Nomascus leucogenys
4929 Homo sapiens
54278 Rattus norvegicus
424320 Gallus gallus
100157120 Sus scrofa
540245 Bos taurus
18227 Mus musculus
436679 Danio rerio
478754 Canis lupus familiaris
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