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Browse our Nuclear Receptor Subfamily 5, Group A, Member 1 Proteins (NR5A1)

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Nuclear Receptor Subfamily 5, Group A, Member 1 Proteins (NR5A1)
On www.antibodies-online.com are 6 Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Proteins from 3 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 5, Group A, Member 1 Antibodies (77) and Nuclear Receptor Subfamily 5, Group A, Member 1 Kits (23) and many more products for this protein. A total of 113 Nuclear Receptor Subfamily 5, Group A, Member 1 products are currently listed.
Synonyms:
Ad4bp, Ad4BP/SF-1, ELP, ELP-3, ff1a, ftz, Ftz-F1, FTZ1, Ftzf1, NR5A1, POF7, Sf-1, SF-1/Ad4BP, SF1, SPGF8, SRXY3, zFF1, zFF1A, zFF1B
list all proteins Gene Name GeneID UniProt
NR5A1 2516 Q13285
NR5A1 26423 P33242
NR5A1 83826 P50569

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Nuclear Receptor Subfamily 5, Group A, Member 1 Proteins (NR5A1) by Origin

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More Proteins for Nuclear Receptor Subfamily 5, Group A, Member 1 Interaction Partners

Zebrafish Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. ff1a functions in both slow and fast muscle morphogenesis in response to Hedgehog (show SHH Proteins) signaling, and this function parallels the activity of another slow muscle gene, prox1 (show PROX1 Proteins)

  2. The role of Sox9a in ff1a gene regulation and function was studied using sox9a morpholinos.

Human Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. SF1 SNPs are associated with serum uric acid levels in Chinese males and females.

  2. Describe microcystic stromal tumor as a distinctive ovarian sex cord-stromal neoplasm characterized by FOXL2 (show FOXL2 Proteins), SF-1, WT-1 (show WT1 Proteins), Cyclin D1 (show CCND1 Proteins), and beta-catenin (show CTNNB1 Proteins) nuclear expression and CTNNB1 (show CTNNB1 Proteins) mutations.

  3. These findings demonstrate that in vitro LRH-1 (show NR5A2 Proteins) can act like SF-1 and compensate for its deficiency.

  4. these results demonstrate that ASAH1 (show ASAH1 Proteins) is a novel coregulatory protein that represses SF-1 function by directly binding to the receptor on SF-1 target gene promoters and identify a key role for nuclear lipid metabolism in regulating gene transcription.

  5. SF-1 expression was inhibited by miR23a/b overexpression in eutopic endometrial stromal cells(ESCs (show NR2E3 Proteins)) and upregulated by miR23a/b inhibition in normal ESCs (show NR2E3 Proteins).

  6. Data conclude that SF-1 regulates aromatase (show CYP19A1 Proteins) expression in GCT (show QPCT Proteins); over-expression of LRH-1 (show NR5A2 Proteins) suggests that this receptor may be involved in the pathogenesis of GCT (show QPCT Proteins) by mechanisms other than the regulation of aromatase (show CYP19A1 Proteins).

  7. Although the ventromedial nucleus of the hypothalamus shares a common lineage, it further differentiates into a neuronal cluster devoid of steroidogenic factor (SF)-1.

  8. These results indicated that abundant FDXR (show FDXR Proteins) expression in these steroidogenic cells was maintained through SF-1 binding to the intronic enhancer of the FDXR (show FDXR Proteins) gene

  9. No nuclear SF-1 expression was identified in any of the 127 germ cell tumors

  10. Aberrant SF-1 expression was significantly higher in ovarian sex cord stromal tumors than that of ovarian cancer.

Mouse (Murine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. SF-1 (show SF1 Proteins) is needed for proper development of fetal and adult Leydig cells but with distinct primary functions

  2. NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and beta-catenin (show CTNNB1 Proteins) accumulation

  3. The results suggest that gonadal steroids do not influence the production of neurosteroids in the fetal brain, nor does SF-1 (show SF1 Proteins) play a major role in the regulation of steroidogenic enzyme expression in the brain.

  4. MiR (show MLXIP Proteins)-383 promoted the expression of miR (show MLXIP Proteins)-320 which regulated granulosa cell functions by targeting E2F1 (show E2F1 Proteins) and SF-1 (show SF1 Proteins) proteins.

  5. Data indicate that genetic ablation of the Vanin-1 (Vnn1 (show VNN1 Proteins)) gene in SF-1 (NR5A1) transgenic mice significantly reduced the severity of neoplastic lesions in the adrenal cortex.

  6. FOXL2 (show FOXL2 Proteins) negatively regulates Sf1 (show SF1 Proteins) expression by antagonizing WT1 (show WT1 Proteins)-KTS during early ovarian development in mice

  7. we provide the evidence that the acidic residue (E199) located downstream from the core consensus SUMO site of NR5A1 is, at least in part, required for SUMOylation of NR5A1 and for its mediated target gene and protein expression.

  8. Data suggest that the regulation of StAR by transcription factors including SF-1 (show SF1 Proteins), GATA-4 (show GATA4 Proteins) and C/EBP-beta (show CEBPB Proteins) maybe critical mechanism involved in low-dose MBP (show MBP Proteins)-stimulated steroidogenesis.

  9. Data indicate that reduced numbers of steroidogenic factor 1-positive (SF1 (show SF1 Proteins)(+)) progenitor cells and increased fetal Leydig cells (FLCs), and increased hedgehog (show SHH Proteins) (Hh) activation led to decreased adult Leydig cells (ALCs) populations.

  10. GATA6 (show GATA6 Proteins) regulates the differentiation of steroidogenic (SF-1 (show SF1 Proteins) expressing) progenitors into adrenocortical cells.

Pig (Porcine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. NR5A1 variations influence meat color in a hypothalamus-pituitary-adrenal axis independent manner

Cow (Bovine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) interaction partners

  1. These results indicate that PCBs impair the secretory function of ovarian steroidogenic cells by disrupting steroidogenesis and increasing OT secretion, and the receptor SF-1 appears to be essentially involved in these processes.

  2. The SF-1 and beta-catenin pathway convergence on StarD7 expression may have important implications in the phospholipid uptake and transport, contributing to the normal trophoblast development.

  3. The role of the NR5A1 activating functions AF-1 & AF (show Psmd4 Proteins)-2 was studied in luteinizing bovine theca cells. The regulation of the 3 NR5A1-controlled genes CYPA11, STAR, & INSL3 (show INSL3 Proteins) apparently is not dependent on NR5A1 activating functions AF-1 (show Psmd4 Proteins) or AF-2.

  4. Involvement of Ad4BP/SF-1, DAX-1 (show NR0B1 Proteins), and COUP-TFII (show NR2F2 Proteins) transcription factor on steroid production and luteinization in ovarian theca cells.

  5. GATA4 (show GATA4 Proteins) and GATA6 (show GATA6 Proteins) mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 (show GATA6 Proteins) showed a marked decrease at the regressed luteal stage, like NR5A1, NR5A2 (show NR5A2 Proteins), and the other steroidogenic markers.

Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Protein Profile

Protein Summary

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1)

  • nuclear receptor subfamily 5, group A, member 2 (nr5a2)
  • nuclear receptor subfamily 5, group A, member 1 (NR5A1)
  • nuclear receptor subfamily 5, group A, member 1 (nr5a1)
  • steroidogenic factor 1 (SF-1)
  • nuclear receptor subfamily 5, group A, member 1 (Nr5a1)
  • steroidogenic factor 1-like (LOC100738392)
  • Ad4bp protein
  • Ad4BP/SF-1 protein
  • ELP protein
  • ELP-3 protein
  • ff1a protein
  • ftz protein
  • Ftz-F1 protein
  • FTZ1 protein
  • Ftzf1 protein
  • NR5A1 protein
  • POF7 protein
  • Sf-1 protein
  • SF-1/Ad4BP protein
  • SF1 protein
  • SPGF8 protein
  • SRXY3 protein
  • zFF1 protein
  • zFF1A protein
  • zFF1B protein

Protein level used designations for NR5A1

LRH1 , fushi tarazu , nuclear receptor subfamily 5 group A member 2 , steroidogenic factor 1 , nuclear receptor subfamily 5, group A, member 1 , steroidgenic factor 1 , steroidogenic factor-1 , STF-1 , adrenal 4 binding protein , adrenal 4-binding protein , fushi tarazu factor homolog 1 , nuclear receptor AdBP4 , steroid hormone receptor Ad4BP , steroidogenic factor 1 nuclear receptor , embryonal LTR-binding protein , embryonal long terminal repeat-binding protein , fushi tarazu 1 factor homolog , steroid hydroxylase positive regulator , nuclear receptor subfamily 5 group A member 1 , steroidogenic factor-1 SF-1

GENE ID SPECIES
30749 Danio rerio
751778 Taeniopygia guttata
100271747 Xenopus (Silurana) tropicalis
100534561 Oreochromis niloticus
2516 Homo sapiens
26423 Mus musculus
83826 Rattus norvegicus
609642 Canis lupus familiaris
397368 Sus scrofa
281948 Bos taurus
395960 Gallus gallus
100049145 Xenopus laevis
100033902 Equus caballus
443464 Ovis aries
100738392 Sus scrofa
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