Browse our anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies

Full name:
anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies (PPARA)
On www.antibodies-online.com are 257 Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies from 26 different suppliers available. Additionally we are shipping Peroxisome Proliferator-Activated Receptor alpha Kits (53) and Peroxisome Proliferator-Activated Receptor alpha Proteins (13) and many more products for this protein. A total of 334 Peroxisome Proliferator-Activated Receptor alpha products are currently listed.
Synonyms:
4933429D07Rik, AW742785, hPPAR, LOC100136415, nr1c1, PPAR, PPAR-alpha, PPARALPHA, xppara, xPPARalpha
list all antibodies Gene Name GeneID UniProt
PPARA 19013 P23204
PPARA 25747 P37230
PPARA 5465 Q07869

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Most Popular Reactivities for anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies

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All available anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies

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Top referenced anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies

  1. Human Polyclonal PPARA Primary Antibody for ICC, IHC (fro) - ABIN3044397 : Zhou, Zhang, Xu, Wang: Curcumin ameliorates renal fibrosis by inhibiting local fibroblast proliferation and extracellular matrix deposition. in Journal of pharmacological sciences 2015 (PubMed)
    Show all 3 references for 3044397

  2. Human Polyclonal PPARA Primary Antibody for EIA, FACS - ABIN954264 : Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010 (PubMed)
    Show all 2 references for 954264

  3. Human Polyclonal PPARA Primary Antibody for IF, ELISA - ABIN1532643 : Sher, Yi, McBride, Gonzalez: cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. in Biochemistry 1993 (PubMed)
    Show all 2 references for 1532643

  4. Mouse (Murine) Polyclonal PPARA Primary Antibody for IHC, ELISA - ABIN1043876 : Mukherjee, Jow, Noonan, McDonnell: Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. in The Journal of steroid biochemistry and molecular biology 1995 (PubMed)
    Show all 2 references for 1043876

  5. Cow (Bovine) Polyclonal PPARA Primary Antibody for WB - ABIN223278 : Hennessy, Sheedy, Santamaria, Barbacid, ONeill: Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6. in The Journal of biological chemistry 2011 (PubMed)

  6. Mouse (Murine) Polyclonal PPARA Primary Antibody for FACS, WB - ABIN656834 : Spruiell, Richardson, Cullen, Awumey, Gonzalez, Gyamfi: Role of pregnane X receptor in obesity and glucose homeostasis in male mice. in The Journal of biological chemistry 2014 (PubMed)

  7. Cow (Bovine) Polyclonal PPARA Primary Antibody for WB - ABIN2777733 : Kourimate, Le May, Langhi, Jarnoux, Ouguerram, Zaïr, Nguyen, Krempf, Cariou, Costet: Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. in The Journal of biological chemistry 2008 (PubMed)

  8. Dog (Canine) Polyclonal PPARA Primary Antibody for WB - ABIN2778267 : Sérée, Villard, Pascussi, Pineau, Maurel, Nguyen, Fallone, Martin, Champion, Lacarelle, Savouret, Barra: Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. in Gastroenterology 2004 (PubMed)

  9. Human Polyclonal PPARA Primary Antibody for IF (p), IHC (p) - ABIN753163 : Mölzer, Wallner, Kern, Tosevska, Schwarz, Zadnikar, Doberer, Marculescu, Wagner: Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health. in Scientific reports 2016 (PubMed)

More Antibodies against Peroxisome Proliferator-Activated Receptor alpha Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. our data indicate that PPAR-alpha mediates antimicrobial responses to mycobacterial infection by inducing TFEB (show TFEB Antibodies) and lipid catabolism.

  2. adiponectin (show ADIPOQ Antibodies) inhibited endoplasmic reticulum stress and apoptosis of adipocyte in vivo and in vitro by activating the AMPK (show PRKAA1 Antibodies)/PPARalpha/ATF2 (show ATF2 Antibodies) pathway.

  3. It was concluded that decreased cardiac PPARalpha expression is essential for adaptive metabolic remodeling in hypoxia, but is prevented by dietary fat.

  4. these results indicate that PPAR-a accelerates important pathways for the clearance of a-ClFA, and a-ClFA may, in part, accelerate its catabolism by serving as a ligand for PPAR-a

  5. PPARgamma (show PPARG Antibodies) controls the cancer stem cell niche

  6. In mice fed with a high-fat diet, palmitoleic acid supplementation stimulated the uptake of glucose in liver through activation of AMPK (show PRKAA1 Antibodies) and FGF-21 (show FGF21 Antibodies), and was dependent on PPARalpha.

  7. Myocardial PPARalpha is down-regulated in animals fed a high-fat diet.

  8. FGF21 (show FGF21 Antibodies) is not critical for bone homeostasis or actions of PPARalpha and PPARgamma (show PPARG Antibodies).

  9. Perfluoroalkyl acids addition to activating PPARalpha as a primary target, also have the potential to activate CAR, PPARgamma (show PPARG Antibodies), and ERalpha (show ESR1 Antibodies) as well as suppress STAT5B (show STAT5B Antibodies).

  10. PPARalpha and its target gene expression were significantly increased only in the kidneys of Irbe-treated WT mice.

Xenopus laevis Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

Human Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. Interference with PLIN2 (show PLIN2 Antibodies) and PPARalpha resulted in major alterations in gene expression, especially affecting lipid, glucose, and purine metabolism.

  2. PPARalpha and FXR (show NR1H4 Antibodies) function coordinately to integrate liver energy balance.

  3. An association was found with PPARalpha polymorphism and patients with nicotine dependency and schizophrenia.

  4. PPAR agonists have shown to have anti proliferative effect in squamous cell carcinoma of the head and neck.

  5. Results show that PPARalpha is downregulated and SREBP-1c (show SREBF1 Antibodies) is upregulated in steatosis L-02 cells. These changes increase lipid synthesis and reduce lipid disposal, which ultimately lead to hepatic steatosis.

  6. Perfluoroalkyl acids addition to activating PPARalpha as a primary target, also have the potential to activate CAR, PPARgamma (show PPARG Antibodies), and ERalpha (show ESR1 Antibodies) as well as suppress STAT5B (show STAT5B Antibodies).

  7. The CYP2E1 (show CYP2E1 Antibodies)-PPARalpha axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  8. Studies indicate that natural dietary compounds, including nutrients and phytochemicals, are Peroxisome proliferator-activated receptor alpha (PPARalpha) ligands or modulators.

  9. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (show NR1I2 Antibodies) and PPARalpha in primary human hepatocytes has been presented.

  10. Hepatitis B virus increases the expression of alpha-mannosidases both in vitro and in vivo via activation of the PPARalpha pathway by its envelope protein.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. The c.*636A>G SNP in the PPARA gene can be considered in Polish Landrace breed as a useful genetic marker for adipose tissue accumulation.

  2. The results indicate that the endometrial expression of PPARalpha genes fluctuates during the estrous cycle and pregnancy.

  3. PPARalpha is likely to play a central role in adaptation to fasting in pig liver

  4. Despite expression of PPAR-alpha in porcine myocardium and effects of fenofibrate on systemic metabolism, treatment with this PPAR-alpha activator does not alter myocardial metabolic or contractile responses to I/R in pigs.

  5. FISH localization of 4 BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (show DGAT1 Antibodies) (SSC4p15), PPARA (SSC5p15), ADIPOR1 (show ADIPOR1 Antibodies) (SSC10p13) and CREB (show CREB1 Antibodies) (SSC15q24)

  6. PPAR profiles in bladder smooth muscle (BSM) may contribute to the susceptibility of BSM to lipotoxicity in the metabolic syndrome.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARalpha signal pathway genes as candidate genes and meat FA composition in yaks and cattle exists.

  2. OCTN2 (show SLC22A5 Antibodies) expression and carnitine transport in cattle, as in rodents, are regulated by PPARalpha.

  3. In conclusion, H8H8 haplotype combination of the PPARalpha may be advantageous for heat resistance traits in Chinese Holstein cattle.

  4. Data suggest that PPARalpha (but not PPARgamma (show PPARG Antibodies)) is involved in vasorelaxation of ophthalmic artery in response to endocannabinoids (i.e., anandamide, palmitoylethanolamide); endothelium removal slightly decreases the response to endocannabinoids.

  5. Data from gene profiling experiments in bovine cell line support hypothesis that saturated long-chain fatty acids modulate ruminant lipid metabolism and expression of inflammation mediators with major effects induced via activation of PPARalpha.

  6. Dietary trans fatty acids may affect liver lipid metabolism in post-partum dairy cows through alterations in PPARalpha gene expression.

  7. Oxidized fataprevent an alcohol-induced triacylglycerol accumulation in rats possibly by upregulation of hepatic PPARalpha-responsive genes, whwereas conjugated linoleic acid does not.

  8. The results are consistent with the hypothesis that arachidonic acid acts via PPARalpha to increase PTGS2 (show PTGS2 Antibodies) levels in bovine endometrial stromal cells.

Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antigen Profile

Antigen Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Alternative names and synonyms associated with Peroxisome Proliferator-Activated Receptor alpha (PPARA)

  • peroxisome proliferator-activated receptor alpha (LOC100136415) antibody
  • peroxisome proliferative activated receptor, alpha (PPAR-ALPHA) antibody
  • peroxisome proliferator activated receptor alpha (Ppara) antibody
  • peroxisome proliferator activated receptor alpha (PPAR ALPHA) antibody
  • peroxisome proliferator activated receptor alpha (ppara) antibody
  • peroxisome proliferator-activated receptor alpha (PPARA) antibody
  • peroxisome proliferator-activated receptor alpha (ppara) antibody
  • 4933429D07Rik antibody
  • AW742785 antibody
  • hPPAR antibody
  • LOC100136415 antibody
  • nr1c1 antibody
  • PPAR antibody
  • PPAR-alpha antibody
  • PPARALPHA antibody
  • xppara antibody
  • xPPARalpha antibody

Protein level used designations for PPARA

peroxisome proliferator-activated receptor alpha , ppar alpha , peroxisome proliferator activated receptor alpha , peroxisome proliferator-activated receptor-alpha , nuclear receptor subfamily 1 group C member 1 , PPAR-alpha , peroxisome proliferative activated receptor, alpha , peroxisome proliferator-activated nuclear receptor alpha variant 3 , PPAR alpha , xPPAR alpha

GENE ID SPECIES
100136415 Salmo salar
100356422 Oryctolagus cuniculus
19013 Mus musculus
25747 Rattus norvegicus
443457 Ovis aries
100135604 Cavia porcellus
398843 Xenopus laevis
5465 Homo sapiens
403654 Canis lupus familiaris
496107 Xenopus laevis
374120 Gallus gallus
397239 Sus scrofa
100009308 Oryctolagus cuniculus
281992 Bos taurus
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