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Browse our anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies

Full name:
anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies (PPARA)
On www.antibodies-online.com are 253 Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies from 26 different suppliers available. Additionally we are shipping Peroxisome Proliferator-Activated Receptor alpha Kits (52) and Peroxisome Proliferator-Activated Receptor alpha Proteins (13) and many more products for this protein. A total of 329 Peroxisome Proliferator-Activated Receptor alpha products are currently listed.
Synonyms:
4933429D07Rik, AW742785, hPPAR, LOC100136415, nr1c1, PPAR, PPAR-alpha, PPARALPHA, xppara, xPPARalpha
list all antibodies Gene Name GeneID UniProt
PPARA 19013 P23204
PPARA 25747 P37230
PPARA 5465 Q07869

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Most Popular Reactivities for anti-Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antibodies

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All available anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies

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Top referenced anti-Peroxisome Proliferator-Activated Receptor alpha Antibodies

  1. Cow (Bovine) Monoclonal PPARA Primary Antibody for ChIP, FACS - ABIN152696 : Sumanasekera, Tien, Turpey, Vanden Heuvel, Perdew: Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. in The Journal of biological chemistry 2003 (PubMed)
    Show all 7 references for ABIN152696

  2. Human Polyclonal PPARA Primary Antibody for IF, ELISA - ABIN1532643 : Sher, Yi, McBride, Gonzalez: cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. in Biochemistry 1993 (PubMed)
    Show all 2 references for ABIN1532643

  3. Mouse (Murine) Polyclonal PPARA Primary Antibody for IHC, ELISA - ABIN1043876 : Mukherjee, Jow, Noonan, McDonnell: Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. in The Journal of steroid biochemistry and molecular biology 1995 (PubMed)
    Show all 2 references for ABIN1043876

  4. Human Polyclonal PPARA Primary Antibody for EIA, FACS - ABIN954264 : Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010 (PubMed)
    Show all 2 references for ABIN954264

  5. Mouse (Murine) Polyclonal PPARA Primary Antibody for IHC, ELISA - ABIN105798 : Zak, Gelebart, Lai: Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis. in Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2010 (PubMed)

  6. Mouse (Murine) Polyclonal PPARA Primary Antibody for FACS, WB - ABIN656834 : Spruiell, Richardson, Cullen, Awumey, Gonzalez, Gyamfi: Role of pregnane X receptor in obesity and glucose homeostasis in male mice. in The Journal of biological chemistry 2014 (PubMed)

  7. Cow (Bovine) Polyclonal PPARA Primary Antibody for WB - ABIN2777734 : Kourimate, Le May, Langhi, Jarnoux, Ouguerram, Zaïr, Nguyen, Krempf, Cariou, Costet: Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. in The Journal of biological chemistry 2008 (PubMed)

  8. Dog (Canine) Polyclonal PPARA Primary Antibody for WB - ABIN2778267 : Sérée, Villard, Pascussi, Pineau, Maurel, Nguyen, Fallone, Martin, Champion, Lacarelle, Savouret, Barra: Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. in Gastroenterology 2004 (PubMed)

More Antibodies against Peroxisome Proliferator-Activated Receptor alpha Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. PPAR-alpha activation during pressure-overloaded heart failure improved myocardial function and energetics.

  2. These studies conclusively show that cell proliferation is mediated exclusively by PPARA activation in hepatocytes and that Kupffer cell PPARA has an important role in mediating the anti-inflammatory effects of PPARA agonists.

  3. PPARalpha expression supports the hyperdynamic cardiac response early in the course of sepsis and that increased fatty acid oxidation may prevent morbidity and mortality.

  4. Phospho-AMPK (show PRKAA1 Antibodies) is a molecular switch able to cooperate with glucocorticoid receptors and Ppar-alpha at the chromatin level, a novel adaptation mechanism to prolonged fasting.

  5. These data raise the possibility that ATGL (show PNPLA2 Antibodies) deficiency could impair the renal fatty acid metabolism though inhibiting PPARalphaexpression, which may lead to lipid deposition and cell apoptosis of PCT (show UROD Antibodies), and finally contribute to the renal fibrosis and dysfunction

  6. GRbeta antagonizes the GC-induced signaling during fasting via GRalpha and the PPARalpha-FGF21 (show FGF21 Antibodies) axis that reduces fat burning. Furthermore, hepatic GRbeta increases inflammation, which leads to hepatic lipid accumulation.

  7. These findings reveal a novel BVRA (show BLVRA Antibodies)-GSKbeta-PPARalpha axis that regulates hepatic lipid metabolism and may provide unique targets for the treatment of non-alcoholic fatty liver disease.

  8. CYP2A5 protects against the development of alcoholic fatty liver disease, and the PPARalpha-FGF21 axis contributes to the protective effects of CYP2A5 on alcoholic fatty liver disease.

  9. This study indicates that PPAR alpha activation drives demethylation of the CpG islands of the Gadd45b (show GADD45B Antibodies) promoter in the mouse liver and that epigenetic change at the Gadd45b (show GADD45B Antibodies) promoter is critical for Gadd45b (show GADD45B Antibodies) induction.

  10. Cyp1b1 (show CYP1B1 Antibodies) affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4alpha (show HNF4A Antibodies) and PPARalpha.

Xenopus laevis Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

Human Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. The CYP2E1 (show CYP2E1 Antibodies)-PPARalpha axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  2. Studies indicate that natural dietary compounds, including nutrients and phytochemicals, are Peroxisome proliferator-activated receptor alpha (PPARalpha) ligands or modulators.

  3. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (show NR1I2 Antibodies) and PPARalpha in primary human hepatocytes has been presented.

  4. Hepatitis B virus increases the expression of alpha-mannosidases both in vitro and in vivo via activation of the PPARalpha pathway by its envelope protein.

  5. PPARalpha activation plays defensive and compensative roles by reducing cellular toxicity associated with fatty acids and sulfuric acid.

  6. PPARalpha/gamma agonist, elafibranor resolves nonalcoholic steatohepatitis without worsening fibrosis.

  7. The effects of fenofibrate on nonalcoholic fatty liver disease in the context of PPAR-alpha activation was studied.

  8. PPARA polymorphism is associated with the risk of coronary heart disease.

  9. Telmisartan improved the hyperglycemia-induced cardiac fibrosis through the PPARdelta (show PPARD Antibodies)/STAT3 (show STAT3 Antibodies) pathway.

  10. A modest relationship was found between PPARalpha and AIP (show AIP Antibodies) expression, both being significantly higher in the presence of pre-operative somatostatin (show SST Antibodies) analogues in somatotropinoma patients.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. The c.*636A>G SNP in the PPARA gene can be considered in Polish Landrace breed as a useful genetic marker for adipose tissue accumulation.

  2. The results indicate that the endometrial expression of PPARalpha genes fluctuates during the estrous cycle and pregnancy.

  3. PPARalpha is likely to play a central role in adaptation to fasting in pig liver

  4. Despite expression of PPAR-alpha in porcine myocardium and effects of fenofibrate on systemic metabolism, treatment with this PPAR-alpha activator does not alter myocardial metabolic or contractile responses to I/R in pigs.

  5. FISH localization of 4 BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (show DGAT1 Antibodies) (SSC4p15), PPARA (SSC5p15), ADIPOR1 (show ADIPOR1 Antibodies) (SSC10p13) and CREB (show CREB1 Antibodies) (SSC15q24)

  6. PPAR profiles in bladder smooth muscle (BSM) may contribute to the susceptibility of BSM to lipotoxicity in the metabolic syndrome.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARalpha signal pathway genes as candidate genes and meat FA composition in yaks and cattle exists.

  2. OCTN2 (show SLC22A5 Antibodies) expression and carnitine transport in cattle, as in rodents, are regulated by PPARalpha.

  3. In conclusion, H8H8 haplotype combination of the PPARalpha may be advantageous for heat resistance traits in Chinese Holstein cattle.

  4. Data suggest that PPARalpha (but not PPARgamma (show PPARG Antibodies)) is involved in vasorelaxation of ophthalmic artery in response to endocannabinoids (i.e., anandamide, palmitoylethanolamide); endothelium removal slightly decreases the response to endocannabinoids.

  5. Data from gene profiling experiments in bovine cell line support hypothesis that saturated long-chain fatty acids modulate ruminant lipid metabolism and expression of inflammation mediators with major effects induced via activation of PPARalpha.

  6. Dietary trans fatty acids may affect liver lipid metabolism in post-partum dairy cows through alterations in PPARalpha gene expression.

  7. Oxidized fataprevent an alcohol-induced triacylglycerol accumulation in rats possibly by upregulation of hepatic PPARalpha-responsive genes, whwereas conjugated linoleic acid does not.

  8. The results are consistent with the hypothesis that arachidonic acid acts via PPARalpha to increase PTGS2 (show PTGS2 Antibodies) levels in bovine endometrial stromal cells.

Peroxisome Proliferator-Activated Receptor alpha (PPARA) Antigen Profile

Antigen Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Alternative names and synonyms associated with Peroxisome Proliferator-Activated Receptor alpha (PPARA)

  • peroxisome proliferator-activated receptor alpha (LOC100136415) antibody
  • peroxisome proliferative activated receptor, alpha (PPAR-ALPHA) antibody
  • peroxisome proliferator activated receptor alpha (Ppara) antibody
  • peroxisome proliferator activated receptor alpha (PPAR ALPHA) antibody
  • peroxisome proliferator activated receptor alpha (ppara) antibody
  • peroxisome proliferator-activated receptor alpha (PPARA) antibody
  • peroxisome proliferator-activated receptor alpha (ppara) antibody
  • 4933429D07Rik antibody
  • AW742785 antibody
  • hPPAR antibody
  • LOC100136415 antibody
  • nr1c1 antibody
  • PPAR antibody
  • PPAR-alpha antibody
  • PPARALPHA antibody
  • xppara antibody
  • xPPARalpha antibody

Protein level used designations for PPARA

peroxisome proliferator-activated receptor alpha , ppar alpha , peroxisome proliferator activated receptor alpha , peroxisome proliferator-activated receptor-alpha , nuclear receptor subfamily 1 group C member 1 , PPAR-alpha , peroxisome proliferative activated receptor, alpha , peroxisome proliferator-activated nuclear receptor alpha variant 3 , PPAR alpha , xPPAR alpha

GENE ID SPECIES
100136415 Salmo salar
100356422 Oryctolagus cuniculus
19013 Mus musculus
25747 Rattus norvegicus
443457 Ovis aries
100135604 Cavia porcellus
398843 Xenopus laevis
5465 Homo sapiens
403654 Canis lupus familiaris
496107 Xenopus laevis
374120 Gallus gallus
397239 Sus scrofa
100009308 Oryctolagus cuniculus
281992 Bos taurus
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