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Browse our Retinoic Acid Receptor alpha Proteins (RARA)

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Retinoic Acid Receptor, alpha Proteins (RARA)
On are 18 Retinoic Acid Receptor, alpha (RARA) Proteins from 8 different suppliers available. Additionally we are shipping Retinoic Acid Receptor alpha Antibodies (189) and Retinoic Acid Receptor alpha Kits (20) and many more products for this protein. A total of 237 Retinoic Acid Receptor alpha products are currently listed.
HS-RARa, Nr1b1, RAR, rar-alpha, RAR-ALPHA1, rara2a, RARalpha1
list all proteins Gene Name GeneID UniProt
RARA 5914 P10276
RARA 19401 P11416
RARA 24705  

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Retinoic Acid Receptor alpha Proteins (RARA) by Origin

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Top referenced Retinoic Acid Receptor alpha Proteins

  1. Human Retinoic Acid Receptor alpha Protein expressed in Escherichia coli (E. coli) - ABIN667055 : Gillespie, Gudas: Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN667055

  2. Human Retinoic Acid Receptor alpha Protein expressed in Wheat germ - ABIN1317431 : Schulz, Paus, Frey, Schmid, Kohl, Mennerich, Winkler, Gillardon: Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells. in PLoS ONE 2011 (PubMed)

More Proteins for Retinoic Acid Receptor alpha Interaction Partners

Human Retinoic Acid Receptor, alpha (RARA) interaction partners

  1. Low expression of RARalpha was independently associated with worse progression-free survival following platinum-based chemotherapy of advanced Non-small cell lung cancer.

  2. The classical counterpart of RARalpha, retinoid X receptor alpha (RXRalpha (show RXRA Proteins)), was down-regulated in both cytoplasm and nucleus of A549 cells upon atRA addition.

  3. RAI1 (show DOM3Z Proteins) polymorphisms rs4925102 and rs9907986 are predicted to disrupt the binding of retinoic acid RXR-RAR receptors and the transcription factor DEAF1 (show DEAF1 Proteins), respectively, in Smith-Magenis and Potocki-Lupski syndromes patients.

  4. Data suggest that hematopoietically expressed homeobox protein (HHEX (show HHEX Proteins)) downmodulation by promyelocytic leukemia (show PML Proteins)-retinoic acid receptor alpha fusion oncoprotein (PML (show PML Proteins)-RARalpha) is a key event during acute promyelocytic leukemia (show PML Proteins) (APL (show FASL Proteins)) pathogenesis.

  5. ATRA dramatically down regulated RARalpha protein levels and led to more DNA damage and ultimately resulted in the synergism of these two agents

  6. NPM (show NPM1 Proteins)-RAR binding to TRADD (show TRADD Proteins) selectively inhibits caspase (show CASP3 Proteins) activation, while allowing activation of NFkappaB (show NFKB1 Proteins) and JNK (show MAPK8 Proteins)

  7. Suggest a novel role of PCGF2 (show PCGF2 Proteins) in arsenic trioxide-mediated degradation of PML (show PML Proteins)-RARA that PCGF2 (show PCGF2 Proteins) might act as a negative regulator of UBE2I (show UBE2I Proteins) via direct interaction.

  8. down-regulation of the level of RAR alpha leads to increased expression of VDR (show CYP27B1 Proteins) in acute myeloid leukemia (show BCL11A Proteins).

  9. Methylated arsenic metabolites bind to PML (show PML Proteins) protein but do not induce cellular differentiation and PML (show PML Proteins)-RARalpha protein degradation in acute promyelocytic leukemia (show PML Proteins).

  10. Novel insight into the functional difference of acquired mutations of PML (show PML Proteins)-RARA both in vitro and in the clinical setting.

Mouse (Murine) Retinoic Acid Receptor, alpha (RARA) interaction partners

  1. Retinoic acid receptor alpha agonist all trans retinoic acid can protect the liver from ischemia reperfusion injury by promoting autophagy, which is dependent on Foxo3 (show FOXO3 Proteins)/p-Akt (show AKT1 Proteins)/Foxo1 (show FOXO1 Proteins) signaling.

  2. both the PML (show PML Proteins)-RARA-driven competitive transplantation advantage and development of acute promyelocytic leukemia (show PML Proteins) (APL (show FASL Proteins)) required DNMT3A (show DNMT3A Proteins)

  3. the reprogramming of epiblast stem cells into embryonic stem cell-like cells also requires low levels of retinoic acid (RA), which can modulate Wnt (show WNT2 Proteins) signalling through physical interactions of RARs (show RARS Proteins) with beta-catenin (show CTNNB1 Proteins).

  4. our findings challenge the predominant model in the field and we propose that PML (show PML Proteins)/RARA initiates leukemia by subtly shifting cell fate decisions within the promyelocyte compartment.

  5. DNA-binding-defective PML (show PML Proteins)/RARA mutants could not repress the transcription of retinoic acid regulated genes.

  6. although X-RARA fusion proteins have been suggested to act by blocking retinoid-dependent transcriptional programs , we observed a surprising paucity of natural retinoids capable of transactivating Gal4 (show LGALS4 Proteins)-RARA in primary mouse bone marrow cells

  7. The results indicate a physiological role for RARgamma as a negative regulator of osteoclastogenesis in vivo and in vitro, and reveal distinct influences of RARalpha and RARgamma in bone structure regulation.

  8. Data suggest that retinoic acid and GM-CSF (show CSF2 Proteins)-induced retinal dehydrogenase 2 (RALDH2 (show ALDH1A2 Proteins)) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (show SP1 Proteins) via the RA receptor/retinoid X receptor (show RXRB Proteins) complex to the Aldh1a2 (show ALDH1A1 Proteins) promoter.

  9. Retinoic acid-RARalpha as a key component of the regulatory network governing maintenance and plasticity of Th1 (show HAND1 Proteins)-cell fate.

  10. atRA signaling mediated by RARa is required in the adult pancreas for maintaining both beta-cell function and mass

Cow (Bovine) Retinoic Acid Receptor, alpha (RARA) interaction partners

  1. Increased expression of mammary TRbeta1 (show THRB Proteins) and DIO2 (show DIO2 Proteins), and decreased RXRalpha (show RXRA Proteins), provide a mechanism to increase thyroid hormone (show PTH Proteins) activity within the mammary gland during lactation.

Xenopus laevis Retinoic Acid Receptor, alpha (RARA) interaction partners

  1. results show role for retinoic acid receptor (show RARB Proteins) as a regulator of spatial patterning of the pre-placodal ectoderm (PPE)through Tbx1 and RIPPLY3 (show DSCR6 Proteins); demonstrate that Ripply3 (show DSCR6 Proteins), acting downstream of RAR (show RAB40B Proteins) signaling, is key player in establishing boundaries in the PPE

Retinoic Acid Receptor alpha (RARA) Protein Profile

Protein Summary

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

Alternative names and synonyms associated with Retinoic Acid Receptor alpha (RARA)

  • retinoic acid receptor alpha (rar-alpha)
  • retinoic acid receptor, alpha (RARA)
  • retinoic acid receptor alpha (LOC396709)
  • retinoic acid receptor alpha (RARALPHA)
  • retinoic acid receptor alpha-2 (rara)
  • retinoic acid receptor, alpha (Rara)
  • retinoic acid receptor, alpha (rara)
  • HS-RARa protein
  • Nr1b1 protein
  • RAR protein
  • rar-alpha protein
  • RAR-ALPHA1 protein
  • rara2a protein
  • RARalpha1 protein

Protein level used designations for RARA

retinoic acid receptor alpha , retinoic acid receptor, alpha , retinoic acid receptor alpha-like , RAR-alpha , nuclear receptor subfamily 1 group B member 1 , nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form , retinoic acid nuclear receptor alpha variant 1 , retinoic acid nuclear receptor alpha variant 2 , retinoic acid receptor, alpha polypeptide , RAR alpha 1 , rar alpha , xRAR alpha , retinoic acid receptor alpha 1 isoform

100136372 Salmo salar
100410811 Callithrix jacchus
396709 Sus scrofa
100009009 Oryctolagus cuniculus
445948 Takifugu rubripes
5914 Homo sapiens
19401 Mus musculus
24705 Rattus norvegicus
480526 Canis lupus familiaris
534280 Bos taurus
399081 Xenopus laevis
395213 Gallus gallus
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