Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) Retinoid X Receptor alpha Antibodies:
anti-Rat (Rattus) Retinoid X Receptor alpha Antibodies:
anti-Human Retinoid X Receptor alpha Antibodies:
Go to our pre-filtered search.
Human Polyclonal Retinoid X Receptor alpha Primary Antibody for ELISA, WB - ABIN2476395
Stewart, Tuffnell: Cloning the cDNA for horse growth hormone and expression in Escherichia coli. in Journal of molecular endocrinology 1991
Show all 4 Pubmed References
Human Monoclonal Retinoid X Receptor alpha Primary Antibody for EMSA, IP - ABIN2668713
Subbarayan, Mark, Messadeq, Rustin, Chambon, Kastner: RXRalpha overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRalpha-null fetuses. in The Journal of clinical investigation 2000
Show all 2 Pubmed References
Human Polyclonal Retinoid X Receptor alpha Primary Antibody for ELISA, WB - ABIN250299
Claudel, Leibowitz, Fiévet, Tailleux, Wagner, Repa, Torpier, Lobaccaro, Paterniti, Mangelsdorf, Heyman, Auwerx: Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. in Proceedings of the National Academy of Sciences of the United States of America 2001
These results suggest a mechanism to establish RXR therapeutic targets with significance in neurodegeneration.
The optimal PPARalpha (show PPARA Antibodies)/RXRalpha heterodimer binding sequence was WAWVTRGGBBAHRGKTYA. The single nucleotide substitution, which reduces binding of RXRalpha to DNA, attenuated PPARalpha (show PPARA Antibodies)-induced transcriptional activation, but this is not always true for PPARalpha (show PPARA Antibodies).
A change in the heterodimeric partner of Peroxisome Proliferator Activated Receptor-alpha (show PPARA Antibodies) from retinoid X receptor (show RXRB Antibodies) to Silent information regulator 1 is responsible for the impaired fatty acid metabolism and cardiac dysfunction in the failing heart.
interaction of Wnt and RXR-alpha pathways in hepatocyte development and hepatocellular carcinoma
a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4 (show CDK4 Antibodies)(R24C/R24C) or oncogenic NRAS (show NRAS Antibodies)(Q61K) and altered expression of p53 (show TP53 Antibodies) and PTEN (show PTEN Antibodies)
This uncovered a novel RXR-dependent innate immune regulatory pathway, suggesting that downregulation of RXR expression or RXR antagonist treatment benefits host antiviral response, whereas RXR agonist treatment may increase risk of viral infections.
Data suggest that retinoic acid and GM-CSF (show CSF2 Antibodies)-induced retinal dehydrogenase 2 (RALDH2 (show ALDH1A2 Antibodies)) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (show SP1 Antibodies) via the RA receptor/retinoid X receptor (show RXRB Antibodies) complex to the Aldh1a2 (show ALDH1A1 Antibodies) promoter.
The expression and binding of RXRalpha to CYP3A genes in liver was sex-dependent and regulated by growth hormone secretion.
The depletion of retinoic acid and the inhibition of RXRalpha function in hepatic tumors involve more complex mechanisms besides the activation of RAS/ERK (show EPHB2 Antibodies) pathway.
These observations suggest that beta-apo (show C9orf3 Antibodies)-13-carotenone regulates RXRalpha transcriptional activity by inducing the formation of the "transcriptionally silent" RXRalpha tetramer.
Data suggest that the binding of Z-10 to RXRalpha inhibited the interaction of RXRalpha with PML (show PML Antibodies)-RARalpha (show RARA Antibodies), leading to Z-10's selective induction of PML (show PML Antibodies)-RARalpha (show RARA Antibodies) degradation.
This suggests that hRXRalpha phosphorylation significantly disrupts its nuclear localization, interaction with VDR (show CYP27B1 Antibodies), intra-nuclear trafficking, and binding to chromatin of the hVDR-hRXR complex.
the expression of CAMP, vitamin D receptor (VDR), and the retinoid X receptor (RXR) isoforms in human skin and gingival tissue biopsies and investigated the signaling pathways involved in 1alpha,25-dihydroxyvitamin D3-induced upregulation of CAMP.
data show that RXRalpha expression is increased in miscarriage in endometrial glands and correlation analysis showed that negative correlation between RXRalpha and PPARgamma (show PPARG Antibodies) disappears in miscarriage. This shift is supposable responsible for the loss of regular function in trophoblast and embryonic tissue.
IL-1beta (show IL1B Antibodies) upregulated RXRalpha through activation of NF-kappaB (show NFKB1 Antibodies) signaling.
RXRA rs10776909 allele T is specifically involved in the pathogenesis of ChGN (show CSGALNACT1 Antibodies). This risk allele may be also associated with worse clinical course of ChGN (show CSGALNACT1 Antibodies).
Results suggest that retinoid X receptor (show RXRB Antibodies) (RXR) activation protects retinal pigment epithelium (RPE (show RPE Antibodies)) cells from oxidative stress-induced (show SQSTM1 Antibodies) apoptosis.
Data show that pregnane X receptor/retinoid X receptor PXR/RXR-[alpha], RXR-[beta], or RXR-[gamma] expression was noted in 9 (16.4%), 9 (16.4%), and 10 (18.2%) pancreatic adenocarcinoma cases, respectively.
Retinoid X receptor alpha plays an important role in proliferation of cholangiocarcinoma
Data suggest a potential therapeutic role for the low toxicity synthetic retinoid X receptor (show RXRB Antibodies) selective agonist, UAB30, in neuroblastoma (show ARHGEF16 Antibodies) treatment.
Expression of TauT is differentially regulated by Vitamin D(3) and retinoic acid via formation of VDR and RXR complexes in the nuclei in a cell type-dependent manner.
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.
retinoid X receptor, alpha
, retinoid X receptor alpha
, RXR alpha 1
, nuclear receptor subfamily 2 group B member 1
, retinoic acid receptor RXR-alpha
, retinoid X nuclear receptor alpha
, retinoic acid receptor
, retinoid x receptor alpha
, retinoid X receptor alpha protein
, nuclear receptor subfamily 2 group B member 2-A
, retinoic acid receptor RXR-beta-A
, retinoid X receptor beta-A
, retinoid receptor-epsilon
, retinoid x receptor, epsilon