Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
VDR (show CYP27B1 Proteins) regulates hundreds of myeloid cell genes and that the molecular pathways controlled by VDR (show CYP27B1 Proteins) in these cells are important in maintaining tolerance.
Association of VDR (show CYP27B1 Proteins) polymorphisms with the susceptibility to Hepatitis C virus infection
No association was observed between GC or VDR (show CYP27B1 Proteins) polymorphisms and breast cancer risk. associations between vitamin D-related genetic variants and breast cancer were not observed overall, although the relationships between vitamin D pathway polymorphisms and breast cancer may be modified by menopausal status and breast tumour subtype
meta-analysis demonstrated that Diabetic Retinopathy was significantly associated with VDR (show CYP27B1 Proteins) gene FokI polymorphism.
The study aims to elucidate the roles of 1,25(OH)2D3 and vitamin D receptor (VDR) in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) by regulating the activation of CD4 (show CD4 Proteins)+ T cells and the PKCdelta (show PKCd Proteins)/ERK (show EPHB2 Proteins) signaling pathway.
We did not observe any significantly different results for TLR-2 gene polymorphisms. Vitamin D deficiency, VDR (show CYP27B1 Proteins), and TLR-2 polymorphisms did not affect the 6-month disability.Vitamin D deficiency and VDR (show CYP27B1 Proteins) gene polymorphisms are significantly more prevalent in people with pulmonary and spinal tuberculosis.
Our meta-analysis indicated that vitamin D receptor polymorphisms may be associated with the risk of keratinocyte cancers
Vitamin D deficiency, the BsmI 'B'allele and the TaqI 't' allele point to their direct roles in primary open-angle glaucoma development. However, the causes of 1a, 25-Dihydroxyvitamin D3 deficiency, the changes in the structure and function of VDR (show CYP27B1 Proteins) and the frequency of allele carriers of polymorphisms of VDR (show CYP27B1 Proteins) require further study.
Found a significant difference in genotype frequencies of VDR (show CYP27B1 Proteins) gene FokI polymorphism in patients with diabetic foot ulcer in comparison to those without diabetic foot ulcer (TT+TC vs. CC p=0.04; OR=1.76; 95% CI=1.02-3.05). Moreover, the patients carrying the T allele had a significantly higher level of TBARS (p=0.01).
VDR (show CYP27B1 Proteins) polymorphisms were not associated with the risk of Breast Cancer in the general population as well as Caucasian population.
Reduced Vitamin D receptor is associated with melanoma.
Expression of TauT is differentially regulated by Vitamin D(3) and retinoic acid via formation of VDR and RXR complexes in the nuclei in a cell type-dependent manner.
The expression of TNF-alpha (show TNF Proteins) and VDR in post-angioplasty coronary artery neointimal lesions of hypercholesterolemic swine, was examined.
Vitamin D receptor activation, and inducible nitric oxide synthase (NOS2 (show NOS2 Proteins)), were strongly induced during Cooperia oncophora reinfection. Several canonical pathways associated with NOS2 (show NOS2 Proteins) were impacted.
Two novel SNPs identified in coding region of VDR are associated with growth traits.
Vitamin D and its receptor might be involved in the progression of diabetic nephropathy by regulating transforming growth factor-beta, angiotensinogen (show AGT Proteins) expression and apoptosis of podocytes.
suggest that VD3/VDR inhibits weight gain by activating UCP3 in the muscles.
The major finding of this study is that large intestine VDR (show CYP27B1 Proteins) significantly contributes to whole-body Ca metabolism but that duodenal compensation may prevent the consequences of VDR (show CYP27B1 Proteins) deletion from large intestine and kidney in growing mice.
The present study investigated whether the vitamin D/vitamin D receptor (VDR) pathway may ameliorate lipopolysaccharide (LPS (show TLR4 Proteins))induced ALI through maintaining the integrity of the alveolar epithelial barrier.
Data, including data from studies in knockout mice, suggest that VDR (show CYP27B1 Proteins) regulates expression of ezrin (show EZR Proteins) in enterocytes; however, VDR (show CYP27B1 Proteins) appears not to be involved in morphology of tight junctions and absorption of large molecules in enterocytes.
These data indicate a synergistic crosstalk between 1alpha,25(OH)2D3 and BMP2 (show BMP2 Proteins) toward osteogenesis and mineral deposition, involving both VDR (show CYP27B1 Proteins) and Pdia3 (show PDIA3 Proteins).
study is the first to report an in vivo association between vitamin D, myostatin (show MSTN Proteins), and the regulation of muscle mass
The current study reveals an important and novel mechanism for VDR (show CYP27B1 Proteins) by regulation of epithelial barriers.
VitD3 reinforced physical interaction between placental VDR (show CYP27B1 Proteins) and NF-kappaB (show NFKB1 Proteins) p65 (show NFkBP65 Proteins) subunit.
1,25D3 modulates CD8 (show CD8A Proteins)+ T cell phenotype via recruitment of the VDR (show CYP27B1 Proteins) transcription factor to the promoter region of Cyp11a1 (show CYP11A1 Proteins) leading to prevention of lung allergic responses.
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.
vitamin D3 receptor
, 1,25-dihydroxyvitamin D3 receptor
, nuclear receptor subfamily 1 group I member 1
, vitamin D nuclear receptor variant 1
, vitamin D (1,25-dihydroxyvitamin D3) receptor
, vitamin D receptor
, vitamin D (1,25- dihydroxyvitamin D3) receptor