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Results indicate that AK5 expression significantly decreased in temporal lobe epilepsy: the expression of AK5 in epileptic brain tissue may play important roles in epilepsy, especially refractory epilepsy
Data demonstrate that human adenylate kinase 5 has two separate functional domains and that both have enzymatic activity.
This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
, ATP-AMP transphosphorylase 5
, adenylate kinase 6
, adenylate kinase isoenzyme 5
, adenylate kinase 5
, adenylate kinase isoenzyme 5-like