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Human Polyclonal NME3 Primary Antibody for EIA, IHC (p) - ABIN359315
Negroni, Venturelli, Tanno, Amendola, Ransac, Cesi, Calabretta, Raschellà: Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis. in Cell death and differentiation 2000
Show all 3 references for ABIN359315
Human Polyclonal NME3 Primary Antibody for ELISA, WB - ABIN562009
McDermott, Boissan, Lacombe, Steeg, Horak: Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth. in Clinical & experimental metastasis 2008
Human Polyclonal NME3 Primary Antibody for IHC (p), WB - ABIN391232
Venturelli, Martinez, Melotti, Casella, Peschle, Cucco, Spampinato, Darzynkiewicz, Calabretta: Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. in Proceedings of the National Academy of Sciences of the United States of America 1995
Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer.
Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility.
NME3 protein interacts with RHO signaling cascades to impair sperm motility through hyperactivation of SMOK, the wild-type form of the responder.
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
, NDP kinase 3
, NDP kinase C
, non-metastatic cells 3, protein expressed in
, nucleoside diphosphate kinase 3
, nucleoside diphosphate kinase C
, expressed in non-metastatic cells 3
, nucleoside diphosphate kinase DR-nm23