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|Application / Reactivity||Hamster||Human||Monkey||Mouse (Murine)|
|Western Blotting (WB)||4 Antibodies||169 Antibodies||7 Antibodies||42 Antibodies|
|Proximity Ligation Assay (PLA)||4 Antibodies||1 Antibodies|
|Immunoprecipitation (IP)||62 Antibodies||14 Antibodies||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||2 Antibodies||40 Antibodies||4 Antibodies||10 Antibodies|
|Immunohistochemistry (IHC)||81 Antibodies||17 Antibodies||2 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies||1 Antibodies|
|Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||23 Antibodies|
|Antigen||Ataxia Telangiectasia Mutated (ATM) Antibodies|
|Epitope||AA 1980-2338 Alternatives|
|Reactivity||Hamster, Human, Monkey, Mouse (Murine) Alternatives|
|Conjugate||This ATM antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-ATM AntibodyTarget Details ATM Application Details Handling Images
|Specificity||This antibody recognises the ATM protein.|
|Immunogen||Recombinant human ATM fragment (amino acids 1980-2338)|
Target Details ATMProduct Details anti-ATM Antibody Application Details Handling Images back to top
|Alternative Name||ATM (ATM Antibody Abstract)|
|Background||ATM Protein is a 350kD polypeptide that is the product of the ATM gene. The ATM gene is defective in Ataxia telangiectasia. ATM protein is expressed within the nucleus of all normal cells, and is thought to be important in detection of DNA damage.Synonyms: A-T mutated, ATDC, Ataxia telangiectasia mutated, Serine-protein kinase ATM, TEL1, TELO1|
|Research Area||Cancer, DNA/RNA|
|Pathways||p53 Signaling, Apoptosis, DNA Damage Repair|
Application DetailsProduct Details anti-ATM Antibody Target Details ATM Handling Images back to top
Western Blot: 1/500 - 1/1000. Immunohistochemistry on paraffin sections: 1:50, this product does require antigen retrieval using heat treatment prior to staining of paraffin sections, we recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with ABIN121486 is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-ATM Antibody Target Details ATM Application Details Images back to top
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
|Expiry Date||12 months|