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anti-Human ATM antibody for Immunofluorescence

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
pSer1981
67
28
17
13
13
13
7
7
7
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
280
74
28
6
4
1
1
Host
Rabbit
204
53
14
8
3
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
8
8
7
7
6
6
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Dot Blot (DB), Immunofluorescence (IF)
158
79
72
50
39
36
23
21
16
11
6
4
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN389888
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.31815147 ABIN2668604 ICC IF Mouse IgG1 kappa pSer1981 Log in to see 10H11-E-12 2
0.31815147 ABIN189039 ICC IF IHC (p) IP IHC WB Rabbit IgG Ser1981 Log in to see Y170
0.31815147 ABIN513576 IF ELISA Mouse IgG2a kappa AA 1-138, full length Log in to see 2C10
0.31815147 ABIN2406834 IF IHC WB Rabbit IgG pSer1981 Log in to see Polyclonal
0.0010831101 ABIN251422 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 3
0.0010831101 ABIN319313 IF WB Rabbit Ser1981 Log in to see Polyclonal 4
0.0010831101 ABIN362751 IF WB Rabbit IgG AA 1979-1983 Log in to see Polyclonal 5
0.0010831101 ABIN258963 ICC IF IHC (p) IP IHC WB Rabbit IgG Ser1981 Log in to see EP1890Y
0.0010831101 ABIN151622 ICC IF WB Mouse IgG1 AA 980-1512 Log in to see 5C2
0.0010831101 ABIN152102 ICC IF IHC (p) IP IHC PLA WB Rabbit AA 2550-2600 Log in to see Polyclonal
0.0010831101 ABIN151775 ICC IF IHC (p) IP IHC ELISA WB Mouse IgG1 AA 2577-3056 Log in to see 2C1
0.0010831101 ABIN1976853 IF WB Rabbit AA 1979-1983 Log in to see Polyclonal
0.0010831101 ABIN221229 IF IP IHC WB Mouse IgG1 AA 2577-3056 Log in to see 2C1
0.0010831101 ABIN363380 ICC FACS IF IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0010831101 ABIN2882455 IF Rabbit IgG pSer1981 Log in to see Polyclonal
0.0010831101 ABIN2617305 IF IHC (p) IP WB Mouse IgG1 AA 2577-3056 Log in to see 2C1
0.0010831101 ABIN1976855 IF IP IHC (p) PLA WB Rabbit IgG AA 2550-2600 Log in to see Polyclonal
0.0010831101 ABIN1976857 IF IHC (p) Rabbit IgG AA 2550-2600 Log in to see Polyclonal
0.0010831101 ABIN1827407 IF ELISA Mouse IgG2a, kappa Log in to see 2C10
0.0010831101 ABIN1840188 DB IF Rabbit pSer1981 Log in to see Polyclonal

Top referenced anti-ATM antibody for Immunofluorescence

Similar anti-ATM Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies
Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 22 Antibodies
ELISA 79 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 25 Antibodies
Immunofluorescence (IF) 50 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 81 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 40 Antibodies
Immunoprecipitation (IP) 62 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Western Blotting (WB) 170 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope pSer1981
(67), (28), (17), (13), (13), (13), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(280), (74), (28), (6), (4), (1), (1)
Host Rabbit
(204), (53), (14), (8), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This ATM antibody is un-conjugated
(8), (8), (7), (7), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Dot Blot (DB), Immunofluorescence (IF)
(158), (79), (72), (50), (39), (36), (23), (21), (16), (11), (6), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN389888) Images
Specificity This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Clone RB8121
Isotype Ig

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN389888) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.
Synonyms: Serine-protein kinase ATM, Ataxia telangiectasia mutated, A-T, mutated, ATM
Molecular Weight 350644 DA
Gene ID 472
UniProt Q13315
Research Area Cell Signaling, Cell Cycle, Phospho-specific antibodies, Cell Structure
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN389888) Images back to top
Application Notes DB = 1:500, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN389888) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-ATM Antibody (ABIN389888)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Brunet, Gutiérrez-Enríquez, Torres, Bérez, Sanjosé, Galceran, Izquierdo, Menéndez, Gumà, Borràs: "ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations." in: Clinical genetics, Vol. 73, Issue 5, pp. 465-73, 2008

Tsai, Chung, Takahashi, Xu, Hu: "Functional interaction between FOXO3a and ATM regulates DNA damage response." in: Nature cell biology, Vol. 10, Issue 4, pp. 460-7, 2008

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN389888) back to top
Supplier Images
Dot Blot (DB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (pSer1981) (ABIN389888) Dot blot analysis of anti-Phospho-ATM-pS1981 Antibody (ABIN389888) on nitrocellulose ...
Immunofluorescence (IF) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (pSer1981) (ABIN389888) Confocal immunofluorescent analysis ofPhospho-ATM-pS1981 Antibody (ABIN389888) with H...