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anti-Human ATM antibody for Immunofluorescence

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • ataxia telangiectasia mutated homolog (human)
  • tefu
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • AaeL_AAEL014900
  • MGYG_07634
  • PGTG_14279
  • Atm
  • LOC100349299
Epitope
pSer1981
83
41
17
16
16
15
13
8
8
7
7
6
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
348
131
68
20
4
1
1
Host
Rabbit
228
94
17
8
3
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
12
11
10
9
6
6
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Dot Blot (DB), Immunofluorescence (IF)
208
124
106
85
78
68
61
44
27
21
13
4
4
2
2
2
1
1
1
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Catalog No. ABIN389888
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.7607565 ABIN151030 ICC FACS IF IHC (p) IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 74
11.7607565 ABIN2668604 ICC IF Mouse IgG1 kappa pSer1981 Log in to see 10H11-E-12 2
11.7607565 ABIN151622 ICC IF IHC IP WB Mouse IgG1 Log in to see 5C2 26
11.7607565 ABIN1869997 IF IHC WB Rabbit IgG pSer1981 Log in to see Polyclonal
11.7607565 ABIN513576 IF ELISA Mouse IgG2a kappa AA 1-138, full length Log in to see 2C10
11.7607565 ABIN3030033 DB IF ELISA Rabbit Ig Fraction pSer1981 Log in to see Polyclonal
1 ABIN151772 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 15
1 ABIN151775 ChIP ELISA FACS ICC IF IHC IHC (p) IP WB Mouse IgG1 full length Log in to see 2C1 114
1 ABIN152102 ICC IF IHC (p) IP IHC PLA WB Rabbit AA 2550-2600 Log in to see Polyclonal 2
1 ABIN319313 IF WB Rabbit Ser1981 Log in to see Polyclonal 4
1 ABIN362751 IF WB Rabbit IgG AA 1979-1983 Log in to see Polyclonal 5
1 ABIN1882297 IF WB Rabbit IgG Log in to see Polyclonal
1 ABIN4282171 ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282178 ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282188 ICC IF IHC IHC (p) WB DyLight 755 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282199 ICC IF IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282201 ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282170 ICC IF IHC IHC (p) WB DyLight 650 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282173 ICC IF IHC IHC (p) WB DyLight 550 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282200 ICC IF IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12

Top referenced anti-ATM antibody for Immunofluorescence

Similar anti-ATM Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies
Chromatin Immunoprecipitation (ChIP) 2 Antibodies
Dot Blot (DB) 22 Antibodies
ELISA 106 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 44 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 60 Antibodies
Immunofluorescence (IF) 86 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies
Immunohistochemistry (IHC) 123 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antibodies
Immunoprecipitation (IP) 67 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Western Blotting (WB) 207 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope pSer1981
(83), (41), (17), (16), (16), (15), (13), (8), (8), (7), (7), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(348), (131), (68), (20), (4), (1), (1)
Host Rabbit
(228), (94), (17), (8), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This ATM antibody is un-conjugated
(12), (11), (10), (9), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Dot Blot (DB), Immunofluorescence (IF)
(208), (124), (106), (85), (78), (68), (61), (44), (27), (21), (13), (4), (4), (2), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN389888) Images
Specificity This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This Phospho-ATM-pS1981 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1981 of human ATM.
Clone RB8121
Isotype Ig

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN389888) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2,checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. ATM and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in the gene encoding ATM are associated with ataxia telangiectasia, an autosomal recessive disorder.
Synonyms: Serine-protein kinase ATM, Ataxia telangiectasia mutated, A-T, mutated, ATM
Molecular Weight 350644 DA
Gene ID 472
UniProt Q13315
Research Area Cell Signaling, Cell Cycle, Phospho-specific antibodies, Cell Structure
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN389888) Images back to top
Application Notes DB = 1:500, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN389888) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-ATM Antibody (ABIN389888)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Brunet, Gutiérrez-Enríquez, Torres, Bérez, Sanjosé, Galceran, Izquierdo, Menéndez, Gumà, Borràs: "ATM germline mutations in Spanish early-onset breast cancer patients negative for BRCA1/BRCA2 mutations." in: Clinical genetics, Vol. 73, Issue 5, pp. 465-73, 2008

Tsai, Chung, Takahashi, Xu, Hu: "Functional interaction between FOXO3a and ATM regulates DNA damage response." in: Nature cell biology, Vol. 10, Issue 4, pp. 460-7, 2008

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN389888) back to top
Supplier Images
Dot Blot (DB) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (pSer1981) (ABIN389888) Dot blot analysis of anti-Phospho-ATM-pS1981 Antibody (ABIN389888) on nitrocellulose ...
Immunofluorescence (IF) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (pSer1981) (ABIN389888) Confocal immunofluorescent analysis ofPhospho-ATM-pS1981 Antibody (ABIN389888) with H...