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anti-Mouse (Murine) ATM antibody for Flow Cytometry

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
phosphorylated
86
37
17
14
13
13
13
7
7
7
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
320
113
59
14
6
4
1
Host
Mouse
214
83
14
8
3
Clonality
Monoclonal
Conjugate
This ATM antibody is conjugated to PE
10
10
8
8
6
6
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS)
197
111
99
89
77
74
53
23
22
13
11
4
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2662388
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010463598 ABIN2662389 FACS PE Mouse IgG1 kappa phosphorylated Log in to see 10H11-E12 3
0.0010463598 ABIN363380 ICC FACS IF IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN1721458 ChIP ICC FACS IF IP IHC ELISA WB Mouse IgG1 kappa Log in to see 2C1
0.0010463598 ABIN4282195 ELISA FACS ICC IF IHC IHC (p) IP WB Alexa Fluor 405 Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282196 ELISA FACS ICC IF IHC IHC (p) IP WB Alexa Fluor 488 Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282197 ELISA FACS ICC IF IHC IHC (p) IP WB Alexa Fluor 647 Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282198 ELISA FACS ICC IF IHC IHC (p) IP WB Alexa Fluor 700 Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282167 ELISA FACS ICC IF IHC IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282174 ELISA FACS IHC IHC (p) IP WB FITC Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282176 FACS PE Rabbit C-Term Log in to see Polyclonal
0.0010463598 ABIN4282177 ELISA FACS ICC IF IHC IHC (p) IP WB DyLight 405 Rabbit C-Term Log in to see Polyclonal

Top referenced anti-ATM antibody for Flow Cytometry

Similar anti-ATM Antibodies

Application / Reactivity Human Mouse (Murine)
Western Blotting (WB) 209 Antibodies 81 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies 1 Antibodies
Immunoprecipitation (IP) 101 Antibodies 53 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antibodies 48 Antibodies
Immunohistochemistry (IHC) 120 Antibodies 56 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 12 Antibodies
Immunofluorescence (IF) 87 Antibodies 57 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 62 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope phosphorylated
(86), (37), (17), (14), (13), (13), (13), (7), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(320), (113), (59), (14), (6), (4), (1)
Host Mouse
(214), (83), (14), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ATM antibody is conjugated to PE
(10), (10), (8), (8), (6), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS)
(197), (111), (99), (89), (77), (74), (53), (23), (22), (13), (11), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN2662388) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 10H11-E12
Isotype IgG1 kappa

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling References for anti-ATM Antibody (ABIN2662388) Images back to top
Antigen
Alternative Name ATM (ATM Antibody Abstract)
Background Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair. ATM is held inactive in unirradiated cells as a dimer or higher-order multimer. Cellular irradiation induces rapid intermolecular autophosphorylation of serine 1981 that causes dimer dissociation and initiates cellular ATM kinase activity. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. Mutations in the corresponding ATM gene result in ataxia telangiectasia (AT), an autosomal recessive disease characterized by uncoordinated muscle movement and neurodegeneration. Cells from AT patients display defective DNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage.
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling References for anti-ATM Antibody (ABIN2662388) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details References for anti-ATM Antibody (ABIN2662388) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-ATM Antibody (ABIN2662388)

Product Details anti-ATM Antibody Target Details ATM Application Details Handling Images back to top
Background publications

Tang, Hui, Cui, Garg, Kastan, Xu: "A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage." in: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2559-66, 2008

Bhaskara, Dupré, Lengsfeld, Hopkins, Chan, Lee, Zhang, Gautier, Zakian, Paull: "Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes." in: Molecular cell, Vol. 25, Issue 5, pp. 647-61, 2007

McConville, Stankovic, Byrd, McGuire, Yao, Lennox, Taylor: "Mutations associated with variant phenotypes in ataxia-telangiectasia." in: American journal of human genetics, Vol. 59, Issue 2, pp. 320-30, 1996

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling References for anti-ATM Antibody (ABIN2662388) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (phosphorylated) (PE) (ABIN2662388) anti-Ataxia Telangiectasia Mutated (ATM) (phosphorylated) antibody (PE)