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anti-Rat (Rattus) ATM antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended ATM Antibody (supplied by: Log in to see )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antibodies
  • AI256621
  • at1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • atdc
  • ATE
  • Atm
  • ATM
  • atm
  • atm/tefu
  • C030026E19Rik
  • CG6535
  • dATM
  • Dmel\\CG6535
  • tef
  • Tefu
  • tel1
  • TEL1
  • TELO1
  • telo1
  • Xatm
Epitope
AA 2700-2750
87
41
17
15
13
13
12
7
7
7
7
5
4
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
330
123
61
15
7
4
1
Host
Rabbit
217
87
17
8
3
Clonality
Polyclonal
Conjugate
This ATM antibody is un-conjugated
11
10
9
9
6
6
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
206
118
100
98
84
76
60
22
22
15
10
4
4
3
2
1
1
1
1
Supplier
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Catalog No. ABIN685582
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN884037 IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN884036 IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN884038 IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN884039 IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN685585 IF (cc) IF (p) Cy3 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN685587 IF (cc) IF (p) Cy5.5 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN685588 IF (cc) IF (p) Cy7 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN685589 IF (cc) IF (p) FITC Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN685586 IF (cc) IF (p) Cy5 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN2808094 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 2700-2750 Log in to see Polyclonal
0.0008846439 ABIN679103 IF (p) IHC (p) Rabbit IgG pSer1981 Log in to see Polyclonal

Similar anti-ATM Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Chromatin Immunoprecipitation (ChIP) 1 Antibodies 1 Antibodies
ELISA 15 Antibodies 29 Antibodies
Flow Cytometry (FACS) 2 Antibodies 13 Antibodies
Immunocytochemistry (ICC) 35 Antibodies 55 Antibodies
Immunofluorescence (IF) 35 Antibodies 62 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 35 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 39 Antibodies
Immunoprecipitation (IP) 35 Antibodies
Western Blotting (WB) 43 Antibodies
Biochemical Assay (BCA) 2 Antibodies
BioImaging (BI) 1 Antibodies

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antibodies
Epitope AA 2700-2750
(87), (41), (17), (15), (13), (13), (12), (7), (7), (7), (7), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(330), (123), (61), (15), (7), (4), (1)
Host Rabbit
(217), (87), (17), (8), (3)
Clonality
Polyclonal
Conjugate This ATM antibody is un-conjugated
(11), (10), (9), (9), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(206), (118), (100), (98), (84), (76), (60), (22), (22), (15), (10), (4), (4), (3), (2), (1), (1), (1), (1)
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Product Details anti-ATM Antibody

Target Details ATM Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse ATM
Isotype IgG

Target Details ATM

Product Details anti-ATM Antibody Application Details Handling Images back to top
Antigen
Alternative Name Atm (ATM Antibody Abstract)
Background

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.

Subcellular location: Cytoplasm, Nucleus


Synonyms: AI256621, C030026E19Rik, Serine-protein kinase ATM, Ataxia telangiectasia mutated homolog, A-T mutated homolog, Atm
Gene ID 11920
UniProt Q62388
Research Area Cancer, DNA/RNA
Pathways p53 Signaling, Apoptosis, DNA Damage Repair

Application Details

Product Details anti-ATM Antibody Target Details ATM Handling Images back to top
Application Notes IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-ATM Antibody Target Details ATM Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-ATM Antibody Target Details ATM Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (AA 2700-2750) (ABIN685582) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ATM Polyc...
Immunohistochemistry (IHC) image for anti-ATM antibody (Ataxia Telangiectasia Mutated) (AA 2700-2750) (ABIN685582) Formalin-fixed and paraffin embedded human cervical cancer labeled with Anti-ATM Poly...